Lee County Vacation Rentals

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Our top choices for Lee County vacation rentals

Microwave, oven, stovetop, dishwasher

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Hartsville
10.0 out of 10, Exceptional, (12 reviews)
"Very clean, stayed here for work. Would definitely book again if in the area. "
United States
Kacey
The price is CA $99
CA $213 total
includes taxes & fees
May 25 - May 26
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Fridge, microwave, oven, stovetop

Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (62 reviews)
"The location really is the highlight and the bed is excellent. "
United States
Paul C.
The price is CA $136
CA $245 total
includes taxes & fees
May 28 - May 29
Camden Cottage
2 bedrooms, WiFi, bed sheets

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville
8.0 out of 10, Very good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
The price is CA $103
CA $217 total
includes taxes & fees
Jun 7 - Jun 8
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Interior

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (52 reviews)
"Our third time staying at this home and always have had a great experience. Such a comfy home and very well stocked. Great hosts!"
United States
Kelly W.
The price is CA $184
CA $322 total
includes taxes & fees
May 25 - May 26
Walking distance from one of South Carolina's top Medical centers.
1 bedroom, WiFi, bed sheets

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Camden
10.0 out of 10, Exceptional, (7 reviews)
"Highly recommend to anyone who is young enough to climb the steps and old enough to appreciate the history of this neighborhood/town. Thoughtfully decorated and very cozy. "
United States
Ivy
The price is CA $151
CA $262 total
includes taxes & fees
May 26 - May 27
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Property grounds

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.

Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Camden
9.8 out of 10, Exceptional, (7 reviews)
"we did not see or talk directly to the host; the amenities were all in good condition"
United States
George H.
The price is CA $136
CA $206 total
includes taxes & fees
May 26 - May 27
Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
Dining

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.6 out of 10, Excellent, (4 reviews)
"Convenient location"
United States
Bonney W.
The price is CA $205
CA $694 total
includes taxes & fees
Jun 15 - Jun 16
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Fridge, microwave, oven, stovetop

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Rembert
9.6 out of 10, Exceptional, (34 reviews)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
The price is CA $217
CA $407 total
includes taxes & fees
Jun 1 - Jun 2
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
TV

Quiet, Cozy Cottage in Historic Downtown Camden

Quiet, Cozy Cottage in Historic Downtown Camden
Camden
10.0 out of 10, Exceptional, (1 review)
"Beautiful property with excellent rooms and looks exactly as pictured (if not better)! Check in was super easy and the host communicated with us promptly. The kitchen and huge back yard make this property a gem! "
United States
Grace C.
The price is CA $192
CA $278 total
includes taxes & fees
May 24 - May 25
Quiet, Cozy Cottage in Historic Downtown Camden
Interior

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
9.8 out of 10, Exceptional, (10 reviews)
"It was perfect! And the host was the best everrrr I loved every second I will be returning! "
United States
Kimesha C.
The price is CA $307
CA $391 total
includes taxes & fees
May 28 - May 29
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Fridge, microwave, oven, stovetop

Creekside Country Cottage- minutes away from I-95

Creekside Country Cottage- minutes away from I-95
Manning
10.0 out of 10, Exceptional, (9 reviews)
"Great place beautiful and the dogs loved it"
United States
Jennifer T.
The price is CA $344
CA $626 total
includes taxes & fees
Jun 15 - Jun 16
Creekside Country Cottage- minutes away from I-95
Private kitchen

Charming 1-bedroom house with WiFi, AC in nice Sumter

Charming 1-bedroom house with WiFi, AC in nice Sumter
Sumter
4.0 out of 10, (1 review)
"This was not a regular house but it is a guest house located behind the main house . All my years of booking houses, condos, cabins, and hotels this was definitely not worth 233.00 per night.. no communication with host until check in time. Communication was terrible. "
United States
Derrick M.
The price is CA $206
CA $348 total
includes taxes & fees
Jun 14 - Jun 15
Charming 1-bedroom house with WiFi, AC in nice Sumter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lee County Hotel Reviews

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

6/10 Okay
"Nous avons malheureusement vu un gros insecte dans la douche, probablement un palmetto qui entrait et sortait de la bouche de la douche. C’est probablement dû au système de plomberie."
Gilles 1-night trip
Posted 1 hour ago
Park Inn by Radisson Florence, SC

Find out more about Lee County

Everything you need to know about Lee County vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lee County vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lee County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Lee County vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Lee County. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Lee County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Lee County vacation rentals we have selected for you start as low as CA $206 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Lee County rentals

At Expedia, we put the best Lee County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Lee County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lee County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lee County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.