Des Moines County Vacation Rentals

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Top Vacation Rentals in in Des Moines County

Stroll through the serene garden, surrounded by lush greenery and a tranquil atmosphere.

Homes feature brick exteriors and front porches with a small step leading up to the entrance.

"Great help by the front desk and after hour people."

CA $202 total

includes taxes & fees

Aug 9 - Aug 10

Stunning two-story home with a charming front porch and beautifully manicured lawn.

"Our stay in Nauvoo was absolutely wonderful, thanks to Rebecca and her exceptional apartment. Rebecca was incredibly informative and proactive in her communications before our stay, making everything seamless and stress-free. The apartment itself was immaculate and exceeded our expectations in every way. It had everything we needed, which truly made our time in Nauvoo easy and enjoyable. I highly recommend staying here—Rebecca has created a fantastic experience for her guests!"

CA $133 total

includes taxes & fees

Aug 13 - Aug 14

Kitchen area with dishwasher, double sink, and toaster.

"We had a great stay at this home, we were only there for one night but it matched the description, was clean, easy to find and access and plenty of space for our family. We would stay here again the next time we are in town."

CA $370 total

includes taxes & fees

Aug 24 - Aug 25

Cozy living room with a fireplace, flat-screen TV, and comfortable seating area.

"Location was excellent, had all the necessities. So nice to have the kitchen and make our meals, went to Walmart in Keokuk loaded up on groceries and we were set. Very clean and comfortable. We stayed in march so the weather was perfect. The dollar store is across the street so it was nice to grab anything we needed. Beds were super comfy. "

CA $343 total

includes taxes & fees

Aug 15 - Aug 16

Enjoy cooking in this well-equipped kitchen with microwave and oven, dining table, and natural light from the window.

"Very nice house , as advertised. Will stay again."

CA $224 total

includes taxes & fees

Aug 11 - Aug 12

Enter through the charming circular door, flanked by a gravel path, into this rustic abode.

"Loved the house it was so cute and fun. "

CA $524 total

includes taxes & fees

Aug 31 - Sep 1

Step out onto the deck and enjoy a serene view of the surrounding lawn and trees.

"We had a great stay in Nauvo and communication was great! Thank you so much!!"

CA $308 total

includes taxes & fees

Aug 13 - Aug 14

Enjoy meals on the patio through the sliding glass door, with a dining table and chairs for four.

"I would stay again for sure. Very nice place in a great location. "

CA $393 total

includes taxes & fees

Aug 21 - Aug 22

Guests can enjoy a refreshing swim in the pool.

"Nice place!"

Enjoy the tranquil views from the elevated deck overlooking the calm body of water.

"Loved the view, space, style, amenities. Would definitely stay there again!!! Thank you so much for sharing your place with us. So many wonderful memories created."

CA $614 total

includes taxes & fees

Aug 21 - Aug 22

Surrounded by lush greenery, this serene outdoor space offers a peaceful retreat.

"Nice cabin, worthy of a stay of a 2 or more days. Grateful for the opportunity to stay there and would like to visit it again."

CA $138 total

includes taxes & fees

Aug 14 - Aug 15

Relax in this inviting living area with a comfortable sofa, dining table, and ceiling fan.

"We had a wonderful weekend, quaint little town tucked into the Mississippi Valley. Neighbors were welcoming, enjoyed this stay."

Compact kitchen with dining area, equipped with a stove, refrigerator, and microwave.

"Owner was a great comunicator, appreciated!"

CA $159 total

includes taxes & fees

Aug 18 - Aug 19

Relax on the covered porch with a view of the surrounding grassy area and trees.

"Was an awsome place to stay! It was pleasing to a much needed R&R. Must return soon. Loved it!"

Enjoy cooking in this well-equipped kitchen with a refrigerator, microwave, double oven, and granite countertop.

"I was here for a couple weeks for work, and Rebecca was responsive with any questions, very friendly, and an excellent host!"

CA $286 total

includes taxes & fees

Aug 21 - Aug 22

Enjoy cooking in this well-equipped kitchen with a granite countertop, wooden cabinetry, and a convenient island with stools.

"Had a wonderful time at the Vrbo and enjoyed the towns of Ft. Madison and Nauvoo. "

CA $450 total

includes taxes & fees

Aug 11 - Aug 12

"Outstanding value and extremely nice place, you won't be disappointed. "

CA $270 total

includes taxes & fees

Aug 21 - Aug 22

Relax on the paved patio surrounded by a grassy lawn and a tree, featuring a fire pit and steps leading up to the house.

"I loved it! We were greeted by the host and their dog (who’s friendly as ever!) upon arrival and everything went perfectly smooth from there. The blankets were honestly the best part, LOL! We were all obsessed! Perfect little spot to stay right off the highway in a quiet neighborhood. Will definitely consider it again in the future if I need somewhere to stay near here again! "

CA $241 total

includes taxes & fees

Aug 21 - Aug 22

Guests can enjoy a serene view of the surrounding landscape from the traditional window.

"Our family had a wonderful weekend at the Windmill Farmhouse! "

CA $288 total

includes taxes & fees

Aug 9 - Aug 10

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Top Des Moines County Hotel Reviews

Fun City Resort Hotel

10/10 Excellent

"Convenient location. I like that there is entertainment nearby as the casino is really the only thing going on in town. The rooms are clean and updated. "

Nauvoo Temple House Hotel

10/10 Excellent

"This Hotel was perfect. Loved the old charm for the 1800's and location. It was a bit noisy, but a fan was included in the room so i turned it on to quiet things. Loved seeing the Temple from my room. The bed was comfy and the bathroom so large. Plenty of room to spread out my things. It was a bit dim near the mirror so I had a hand held mirrror for my makeup near the natural window lighting. I would love to stay here again. It was a bit confusing needing to check in down the street, but they did a great job answering any question I had. So kind and friendly."

Find out more about Des Moines County

Everything you need to know about Des Moines County vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Des Moines County vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Des Moines County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Des Moines County vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Des Moines County. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Des Moines County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Des Moines County vacation rentals we have selected for you start as low as CA $69 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Des Moines County rentals

At Expedia, we put the best Des Moines County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Des Moines County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Des Moines County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Des Moines County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Des Moines County Vacation Rentals

Change your mind

Treat yourself

Be picky

Top Vacation Rentals in in Des Moines County

Cozy 1-bedroom mobile home/camper with AC in charming Burlington,Iowa

Nauvoo Vacation Villas & Condos

Fairy Bowery

The Red Front Suite - Sleeps 15

5 Minutes to Downtown Nauvoo - Great Spot for Young Families - Some Stairs

Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.

A four bedroom hobbit hole style home five minutes from historic Nauvoo Illinois

Newly Renovated Full Family Apt. - Centrally Located in Nauvoo - some stairs

Riverside Waterfront on the Mississippi River

Loft cabin #2 near beautiful Cedar River

View Nauvoo and the Mighty Mississippi/Sidon

Riverfront Cabin With Small Beach Short Drive From Nauvoo

Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

Mulholland Garden Apartment

Rustic dog-friendly cabin with fireplace, open layout, grill, W/D, & firepit

Beautiful Riverview Apt Located in Downtown Fort Madison

Historic 1840s Lamoreaux House / Modern Addition

Idyllic Biggsville Vacation Rental: 10 Mi to River

Cozy House

Nauvoo Windmill Farmhouse 10-12 people

Top Des Moines County Hotel Reviews

Fun City Resort Hotel

AmericInn by Wyndham Mount Pleasant

Nauvoo Temple House Hotel

Comfort Suites Burlington

AmericInn by Wyndham West Burlington

The Catfish Bend Inn & Spa

Fairfield Inn & Suites by Marriott Burlington

Hampton Inn & Suites Burlington

Quality Inn & Suites Fort Madison near Hwy 61

Find out more about Des Moines County

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