Uptown
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
CA $33
per adult
100% of travellers recommend
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
CA $21
per traveller
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
CA $83
per adult
Lemp Haunted Neighborhood Walking Tour
CA $35
per adult
84% of travellers recommend
Uptown Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is CA $129 per night from Oct 11 to Oct 12
CA $129
CA $151 total
Oct 11 - Oct 12
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,427 reviews)
"Staff were great, and there was an amazing breakfast. Comfortable bed. Bathroom was awkward and lacked some amenities. Overall a good stay."
Reviewed on Sep 21, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Fully refundable
The price is CA $213 per night from Oct 1 to Oct 2
CA $213
CA $251 total
Oct 1 - Oct 2
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,307 reviews)
"We had a short, but very pleasant stay. The hotel is across the street from the arch, and less than 10 minutes drive to many attractions. Staff was great and very helpful!"
Reviewed on Sep 20, 2026
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is CA $189 per night from Oct 4 to Oct 5
CA $189
CA $221 total
Oct 4 - Oct 5
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is CA $165 per night from Oct 12 to Oct 13
CA $165
CA $195 total
Oct 12 - Oct 13
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (1,167 reviews)
"Nice place. Very clean. Good water pressure. Lol. I enjoyed the art throughout the hotel. The rooftop bar area is really cool. I didn’t try breakfast at the restaurant. Only coffee to go as I was otw out."
Reviewed on Sep 21, 2026
Drury Plaza Hotel St. Louis Union Station
201 S 20th St St. Louis MO
The price is CA $189 per night from Sep 27 to Sep 28
CA $189
CA $225 total
Sep 27 - Sep 28
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,538 reviews)
"Location was great, parking was easy"
Reviewed on Sep 20, 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
The price is CA $201 per night from Oct 11 to Oct 12
CA $201
CA $242 total
Oct 11 - Oct 12
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown
Learn more about Uptown
Eastport
If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Gateway Conference Center are some notable places to visit nearby.
Uptown
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