Uptown

Collinsville

Uptown
Uptown

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Uptown Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is CA $173 per night from May 25 to May 26
CA $173
CA $204 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,060 reviews)
Very clean

Reviewed on May 8, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is CA $136 per night from May 17 to May 18
CA $136
CA $158 total
May 17 - May 18
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,194 reviews)
None

Reviewed on May 8, 2026

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is CA $231 per night from May 10 to May 11
CA $231
CA $277 total
May 10 - May 11
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,823 reviews)
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.

Reviewed on May 6, 2026

21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is CA $221 per night from May 22 to May 23
CA $221
CA $259 total
May 22 - May 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,411 reviews)
Excellent accommodations-exceptional staff-food and drink service was wonderful. Location was perfect.

Reviewed on May 8, 2026

Drury Plaza Hotel St. Louis at the Arch
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
The price is CA $217 per night from May 10 to May 11
CA $217
CA $258 total
May 10 - May 11
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (1,179 reviews)
Very clean. Slightly loud but that's just the environment next to stadium but not enough that it caused issues. Loved the hotel and location.

Reviewed on May 7, 2026

Live by Loews - St.Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is CA $167 per night from May 22 to May 23
CA $167
CA $195 total
May 22 - May 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,959 reviews)
Stay here often always great

Reviewed on May 7, 2026

Pear Tree Inn St. Louis Near Union Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown

early morning Cityscape of St. Louis skyline in Missouri state

Historic Downtown Collinsville

While Historic Downtown Collinsville isn't home to many top sights, Gateway Conference Center and Splash City Family Waterpark are some notable places to visit nearby.

Historic Downtown Collinsville
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Mulberry Hills

While Mulberry Hills isn't home to many top sights, Gateway Conference Center and FanDuel Sportsbook and Horse Racing are some notable places to visit nearby.

Mulberry Hills


Uptown

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