Uptown
Collinsville
Stay near popular Uptown attractions
Things to do
St. Louis Downtown Food Tour: 5 Tastings, BBQ & Local Stories
CA $90
per adult
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
CA $85
per adult
100% of travellers recommend
Uptown Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
The price is CA $201 per night from Nov 9 to Nov 10
CA $201
CA $235 total
Nov 9 - Nov 10
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.6/10 Exceptional! (3,827 reviews)
"Clean room"
Reviewed on Nov 3, 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is CA $147 per night from Nov 8 to Nov 9
CA $147
CA $171 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,513 reviews)
"My room looked clean and I'm glad I sprayed everything down because after a while I saw a bed bug on the bed. It stopped where I sprayed lysol on the bed and I sprayed it again and I think it died. I took a picture, got my stuff and left. I payed for the executive suite on my birthday and a bed bug ..."
Reviewed on Nov 2, 2026
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is CA $175 per night from Nov 25 to Nov 26
CA $175
CA $206 total
Nov 25 - Nov 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
The price is CA $145 per night from Nov 29 to Nov 30
CA $145
CA $170 total
Nov 29 - Nov 30
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
The price is CA $145 per night from Nov 23 to Nov 24
CA $145
CA $170 total
Nov 23 - Nov 24
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $200 per night from Nov 15 to Nov 16
CA $200
CA $241 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas and neighborhoods for the activities you enjoy most. Learn more about Uptown
Learn more about Uptown
Eastport
If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.
Mulberry Hills
While Mulberry Hills isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Historic Downtown Collinsville
While Historic Downtown Collinsville isn't home to many top sights, World's Largest Catsup Bottle and Kruta Bakery are some notable places to visit nearby.
Uptown
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