Title: Book the Best BUSINESS Hotels in Tupelo in 2026 | Expedia.ca [Tupelo Travel Guide](https://expedia.ca/Tupelo.dx6058686)[Hotels in Tupelo](https://expedia.ca/Tupelo-Hotels.d6058686.Travel-Guide-Hotels)[Vacation Rentals in Tupelo](https://expedia.ca/Tupelo-Vacation-Rentals.d6058686.Travel-Guide-VacationRentals)[Flights to Tupelo](https://expedia.ca/Cheap-Flights-To-Tupelo.d6058686.Travel-Guide-Flights)[Tupelo Car Rentals](https://expedia.ca/Car-Rentals-In-Tupelo.d6058686.Car-Rental-Guide)[Tupelo Vacation Packages](https://expedia.ca/Tupelo.d6058686.Destination-Travel-Guides) ![Natchez Trace Parkway, Tennessee and Mississippi, USA](https://images.trvl-media.com/place/6058686/f4642e5a-76da-4382-8a1f-9daf9f79e0c7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058686/f4642e5a-76da-4382-8a1f-9daf9f79e0c7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tupelo Business Hotels Tonight [Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Apr 9 - Apr 10](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-04-09&endDate=2026-04-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Tupelo business-friendly hotels ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/4908d4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/ebb3eb99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/46ec20f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/c64252d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) Tupelo 8.4/10 Very good (1,000 reviews) "Great hotel, close to interstate, very clean and easy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $136 CA $149 total includes taxes & fees Apr 26 - Apr 27 [](https://www.expedia.ca/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/53543e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/e355fdf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/f27f3041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Tupelo Inn & Suites [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) Tupelo 8.8/10 Excellent (1,010 reviews) "Clean room, great staff, great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tekava CA $164 CA $180 total includes taxes & fees May 10 - May 11 [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/f02717f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/6030527c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/6902bc3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/9a4c9a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Tupelo by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) Tupelo 9.4/10 Exceptional (1,002 reviews) "I always stay here when visiting Tupelo, and have never had a bad experience. Staff is friendly, rooms are clean and breakfast is delicious! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martha CA $164 CA $179 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/f9319b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Kitchenette (with Sofabed)](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/648283de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/18cfa99b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/7ca4e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western New Albany [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-New-Albany.h61049.Hotel-Information) New Albany 8.6/10 Excellent (1,000 reviews) "Very nice place to stay clean convenient to the highway and a great breakfast and very friendly people. Stayed the night of three 2526." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) norris CA $128 CA $139 total includes taxes & fees May 4 - May 5 [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-New-Albany.h61049.Hotel-Information) ![Indoor pool, open 11:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2559x3y3-0a134178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3840h2558x0y4-3916fa97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility/Hearing)](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2558x3y4-aaacb4a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2558x3y4-cfdc934f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Tupelo/Barnes Crossing [](https://www.expedia.ca/Tupelo-Hotels-Hampton-Inn-Suites-TupeloBarnes-Crossing.h4326596.Hotel-Information) Tupelo 9.0/10 Wonderful (820 reviews) "Good breakfast and room was comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle CA $205 CA $224 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Tupelo-Hotels-Hampton-Inn-Suites-TupeloBarnes-Crossing.h4326596.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/2dd2ec4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/b4b35f75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/5e403676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/74000000/73090000/73081400/73081348/f1ef089d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Tupelo, a Wyndham Hotel [](https://www.expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) Tupelo 9.6/10 Exceptional (625 reviews) "We had an excellent stay! Staff was super friendly and welcoming. The hotel was really nice, bed was really comfy and the restaurant was delicious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos CA $211 CA $230 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/Tupelo-Hotels-Hotel-Tupelo.h73081348.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/80f7a806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/c42a976c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/06eb4d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) Tupelo 8.2/10 Very good (1,002 reviews) "Great Stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $89 CA $98 total includes taxes & fees Apr 22 - Apr 23 [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/3bb6afaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/33b16390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/70dd7cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) Tupelo 8.6/10 Excellent (1,000 reviews) "Family friendly and Pet friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandro CA $139 CA $152 total includes taxes & fees May 10 - May 11 [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/8d0dca5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/c2002907.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/5cc46626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hotel & Suites Tupelo North by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) Tupelo 9.2/10 Wonderful (1,002 reviews) "Room was great very nice hotel, restaurant fantastic!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hailie CA $155 CA $169 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/e72d69f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/w3997h2667x3y0-600aaa27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/9f8844ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/65d8da63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Fairfield-Inn-Suites-By-Marriott-Tupelo.h4485091.Hotel-Information) Tupelo 8.6/10 Excellent (460 reviews) "Shops and restaurants and shops were convient, however we arrived late and were not able to take advantage of them. A/C was working strong on arrival and we increased temp to our comfort level, it was strong and working. Staff were friendly and efficient. Great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dennis CA $142 CA $155 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/Tupelo-Hotels-Fairfield-Inn-Suites-By-Marriott-Tupelo.h4485091.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-23&endDate=2026-04-24®ionId=6058686&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Tupelo Hotel Reviews ![Fairfield Inn & Suites by Marriott Tupelo](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/e72d69f8_y.jpg) ### Fairfield Inn & Suites by Marriott Tupelo 10/10 Excellent "Clean facility. Friendly staff. Shopping & Restaurants nearby. " [](https://expedia.ca/Tupelo-Hotels-Fairfield-Inn-Suites-By-Marriott-Tupelo.h4485091.Hotel-Information) ![Holiday Inn Express Hotel & Suites Tupelo by IHG](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/15eb656f_y.jpg) ### Holiday Inn Express Hotel & Suites Tupelo by IHG 6/10 Okay "Too expensive for what we received." [](https://expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Baymont by Wyndham Tupelo](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/db91ffba_y.jpg) ### Baymont by Wyndham Tupelo 4/10 Poor "The pictures on the site did not match the condition of the room. I feel like they updated one room to take pictures of to put on the website; but didn't update/repair all of them. There was water damage on the ceiling and the carpeting was old and stained. It smelled very strongly of weed when we walked into the room; and the nice lady at the front desk let us use an air freshener to help with the smell. The smell was still there but less after we left the windows open, turned the ac on, and sprayed the room. The smoke detector had been disabled as well, apparently from the last guests to cover up their smoking. The bed was very uncomfortable as well. We both woke up with terrible back aches the next morning. " [](https://expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Red Roof Inn Tupelo](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5_y.jpg) ### Red Roof Inn Tupelo 8/10 Good "Staff was friendly and helpful " [](https://expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) ![Best Western Plus Tupelo Inn & Suites](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9_y.jpg) ### Best Western Plus Tupelo Inn & Suites 8/10 Good "Breakfast was good. Lots of options. Bery large rooms with comfy beds" [](https://expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![Hampton Inn & Suites Tupelo/Barnes Crossing](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2559x3y3-0a134178_y.jpg) ### Hampton Inn & Suites Tupelo/Barnes Crossing 10/10 Excellent "Beautiful hotel" [](https://expedia.ca/Tupelo-Hotels-Hampton-Inn-Suites-TupeloBarnes-Crossing.h4326596.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Tupelo](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b_y.jpg) ### La Quinta Inn & Suites by Wyndham Tupelo 10/10 Excellent "Very nice room. Great location." [](https://expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Spark by Hilton Tupelo](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/4908d4cd_y.jpg) ### Spark by Hilton Tupelo 10/10 Excellent "In all everything was good would stay there again for sure" [](https://expedia.ca/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) ![Holiday Inn Hotel & Suites Tupelo North by IHG](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/28d227fa_y.jpg) ### Holiday Inn Hotel & Suites Tupelo North by IHG 10/10 Excellent " We did not eat breakfast but the bar was excellent. The personal pizza was great" [](https://expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Tupelo cost? ### What are the best business-friendly hotels in Tupelo? ### How many business-friendly hotels are there in Tupelo? ### What are the best cheap business-friendly hotels in Tupelo? ### What are the top business-friendly motels in Tupelo? ### Are there any family-friendly hotels in Tupelo that are also business friendly? ### Why book your business-friendly hotel in Tupelo with Expedia? ### How can I find cheap business-friendly hotels in Tupelo? ### What is there to do in Tupelo near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [1 Star Hotels in Northeast Mississippi ](https://www.expedia.ca/1Star-Northeast-Mississippi-Hotels.s10-0-d6058679.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Baldwyn ](https://www.expedia.ca/3Star-Baldwyn-Hotels.s30-0-d6354881.Travel-Guide-Filter-Hotels) - 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