Title: Book the Best BUSINESS Hotels in Tupelo in 2026 | Expedia.ca [Tupelo Travel Guide](https://expedia.ca/Tupelo.dx6058686)[Hotels in Tupelo](https://expedia.ca/Tupelo-Hotels.d6058686.Travel-Guide-Hotels)[Vacation Rentals in Tupelo](https://expedia.ca/Tupelo-Vacation-Rentals.d6058686.Travel-Guide-VacationRentals)[Flights to Tupelo](https://expedia.ca/Cheap-Flights-To-Tupelo.d6058686.Travel-Guide-Flights)[Tupelo Car Rentals](https://expedia.ca/Car-Rentals-In-Tupelo.d6058686.Car-Rental-Guide)[Tupelo Vacation Packages](https://expedia.ca/Tupelo.d6058686.Destination-Travel-Guides) ![Tupelo, Mississippi City Hall, is a government building in Tupelo.](https://images.trvl-media.com/place/6058686/ae33cefe-d2f1-4bbf-97ff-5fee4a9debb4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058686/ae33cefe-d2f1-4bbf-97ff-5fee4a9debb4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Tupelo Business Hotels Tonight [Feb 4 - Feb 5](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-02-04&endDate=2026-02-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6058686&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Tupelo business-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/263e981b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/70dd7cef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/272130c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3025200/3025105/3bb6afaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) Tupelo 8.6/10 Excellent (1,000 reviews) "The room was very clean, the staff was exceptional and the hotel is very conveniently located to restaurant." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol CA $128 CA $140 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Tupelo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Tupelo.h3025105.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/e72d69f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/65d8da63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/w3997h2667x3y0-600aaa27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4490000/4485100/4485091/15e0af62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Fairfield-Inn-Suites-By-Marriott-Tupelo.h4485091.Hotel-Information) Tupelo 8.6/10 Excellent (442 reviews) "Worked for our travel. Conveniently located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela CA $134 CA $146 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Tupelo-Hotels-Fairfield-Inn-Suites-By-Marriott-Tupelo.h4485091.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/3f1f0515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/53543e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/f27f3041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Tupelo Inn & Suites [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) Tupelo 8.8/10 Excellent (1,016 reviews) "Very satisfied with all aspects of our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $137 CA $150 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3840000/3837400/3837320/7e0c2900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3840000/3837400/3837320/de44d857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/4000000/3840000/3837400/3837320/106beb40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/4000000/3840000/3837400/3837320/2e1d5380.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Fulton by IHG [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Fulton.h3837320.Hotel-Information) Fulton 8.8/10 Excellent (1,003 reviews) "Friendly staff, good breakfast, comfortable bed." ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Terese CA $126 CA $138 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Fulton.h3837320.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/14000000/13310000/13300600/13300579/e0619abe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/14000000/13310000/13300600/13300579/9dbf189e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/14000000/13310000/13300600/13300579/12e3b6e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/14000000/13310000/13300600/13300579/818da160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Tupelo Barnes Crossing [](https://www.expedia.ca/Tupelo-Hotels-Americas-Best-Value-Inn-Tupelo-Barnes-Crossing.h13300579.Hotel-Information) Tupelo 8.2/10 Very good (720 reviews) "The staff was extra helpful. Key cards and ice machine didn’t work because of ice storm, but that wasn’t under their control. We got the last room, and it was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $67 CA $76 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Tupelo-Hotels-Americas-Best-Value-Inn-Tupelo-Barnes-Crossing.h13300579.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/4908d4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed | Living area](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/cc9ae109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/ebb3eb99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/46ec20f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) Tupelo 8.4/10 Very good (1,000 reviews) "Great overnight stay. Staff was exceptional, room was clean, breakfast was cold items only but that was fine with me. Will definitely stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JULIE CA $134 CA $147 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/f9319b82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/3f63d135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/7ca4e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Kitchenette (with Sofabed)](https://images.trvl-media.com/lodging/1000000/70000/61100/61049/648283de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western New Albany [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-New-Albany.h61049.Hotel-Information) New Albany 8.6/10 Excellent (1,003 reviews) "Nice " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) José CA $114 CA $124 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/Tupelo-Hotels-Best-Western-New-Albany.h61049.Hotel-Information) ![Presidential Studio Suite, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/db91ffba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking, Pool View](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/w2999h2000x0y0-850de2b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/24316019.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/f84f5240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) Tupelo 7.6/10 Good (1,000 reviews) "The room was really good and the lady working the front desk was very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabitha CA $80 CA $87 total includes taxes & fees Feb 18 - Feb 19 [](https://www.expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Indoor pool, open 11:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2559x3y3-0a134178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2558x3y4-cfdc934f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3837h2555x3y3-9a96605b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3840h2558x0y4-3916fa97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Tupelo/Barnes Crossing [](https://www.expedia.ca/Tupelo-Hotels-Hampton-Inn-Suites-TupeloBarnes-Crossing.h4326596.Hotel-Information) Tupelo 9.0/10 Wonderful (792 reviews) "The room was large very clean and the bed was comfortable we booked the hotel because winter storm took out our power ,water,and heat. It was wonderful to be about take a hot shower and I got to have my fur baby safe with me. Love this stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Loretta CA $185 CA $202 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Tupelo-Hotels-Hampton-Inn-Suites-TupeloBarnes-Crossing.h4326596.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/214586c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/06eb4d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/3e72a44d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/16100/16073/c42a976c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Tupelo [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) Tupelo 8.4/10 Very good (1,003 reviews) "The room was clean and in good shape - nice hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darryl [](https://www.expedia.ca/Tupelo-Hotels-Red-Roof-Inn-Tupelo.h16073.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-18&endDate=2026-02-19®ionId=6058686&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Tupelo Hotel Reviews ![Studio 6 Suites Tupelo, MS - North](https://images.trvl-media.com/lodging/2000000/1770000/1765400/1765320/235e5b9f_y.jpg) ### Studio 6 Suites Tupelo, MS - North 10/10 Excellent "Great " [](https://expedia.ca/Tupelo-Hotels-Clarion-Inn-And-Summit-Center.h1765320.Hotel-Information) ![Comfort Inn Tupelo Central](https://images.trvl-media.com/lodging/1000000/120000/116600/116523/0ca0a097_y.jpg) ### Comfort Inn Tupelo Central 10/10 Excellent "nice" [](https://expedia.ca/Tupelo-Hotels-Comfort-Inn.h116523.Hotel-Information) ![Hampton Inn & Suites Tupelo/Barnes Crossing](https://images.trvl-media.com/lodging/5000000/4330000/4326600/4326596/w3840h2558x0y4-3916fa97_y.jpg) ### Hampton Inn & Suites Tupelo/Barnes Crossing 10/10 Excellent "Yes" [](https://expedia.ca/Tupelo-Hotels-Hampton-Inn-Suites-TupeloBarnes-Crossing.h4326596.Hotel-Information) ![Baymont by Wyndham Tupelo](https://images.trvl-media.com/lodging/1000000/130000/124500/124475/97b5a707_y.jpg) ### Baymont by Wyndham Tupelo 10/10 Excellent "The room was really good and the lady working the front desk was very nice " [](https://expedia.ca/Tupelo-Hotels-Baymont-By-Wyndham-Tupelo.h124475.Hotel-Information) ![Hilton Garden Inn Tupelo](https://images.trvl-media.com/lodging/2000000/1520000/1513800/1513705/2ecf5fc2_y.jpg) ### Hilton Garden Inn Tupelo 10/10 Excellent "Yes" [](https://expedia.ca/Tupelo-Hotels-Hilton-Garden-Inn-Tupelo.h1513705.Hotel-Information) ![Holiday Inn Express Hotel & Suites Tupelo by IHG](https://images.trvl-media.com/lodging/1000000/980000/977300/977294/f02717f4_y.jpg) ### Holiday Inn Express Hotel & Suites Tupelo by IHG 10/10 Excellent "Clean room and friendly person at the desk." [](https://expedia.ca/Tupelo-Hotels-Holiday-Inn-Express-Hotel-Suites-Tupelo.h977294.Hotel-Information) ![Spark by Hilton Tupelo](https://images.trvl-media.com/lodging/2000000/1400000/1397800/1397713/f7947b05_y.jpg) ### Spark by Hilton Tupelo 10/10 Excellent "Hotel was clean, modern, and staff was very friendly." [](https://expedia.ca/Tupelo-Hotels-Spark-By-Hilton-Tupelo.h1397713.Hotel-Information) ![Holiday Inn Hotel & Suites Tupelo North by IHG](https://images.trvl-media.com/lodging/1000000/10000/3900/3885/c2002907_y.jpg) ### Holiday Inn Hotel & Suites Tupelo North by IHG 10/10 Excellent "All very good" [](https://expedia.ca/Tupelo-Hotels-Holiday-Inn-Hotel-Suites-Tupelo-North.h3885.Hotel-Information) ![Best Western Plus Tupelo Inn & Suites](https://images.trvl-media.com/lodging/5000000/4540000/4537500/4537402/2eb203b9_y.jpg) ### Best Western Plus Tupelo Inn & Suites 10/10 Excellent "The staff was great.they made a bad weekend great" [](https://expedia.ca/Tupelo-Hotels-Best-Western-Plus-Tupelo-Inn-Suites.h4537402.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Tupelo cost? ### What are the best business-friendly hotels in Tupelo? ### How many business-friendly hotels are there in Tupelo? ### What are the best cheap business-friendly hotels in Tupelo? ### What are the top business-friendly motels in Tupelo? ### Are there any family-friendly hotels in Tupelo that are also business friendly? ### Why book your business-friendly hotel in Tupelo with Expedia? ### How can I find cheap business-friendly hotels in Tupelo? ### What is there to do in Tupelo near my business-friendly hotel? ## Explore a world of travel with Expedia - 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