Title: Best Hotels Near Seacoast Science Center, Rye from CA $112 | Expedia.ca [Vacation Rentals in Rye](https://expedia.ca/Rye-Vacation-Rentals.d154187.Travel-Guide-VacationRentals)[Flights to Rye](https://expedia.ca/Cheap-Flights-To-Rye.d154187.Travel-Guide-Flights)[Seacoast Science Center Car Rentals](https://expedia.ca/Car-Rentals-In-Seacoast-Science-Center.d6173778.Car-Rental-Guide)[Seacoast Science Center Vacations](https://expedia.ca/Seacoast-Science-Center-Rye.d6173778.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Seacoast Science Center, Rye from CA $112 ### Change your mind Book hotels with free cancellation ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 6 - Oct 7](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2025-10-06&endDate=2025-10-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 7 - Oct 8](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2025-10-07&endDate=2025-10-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Seacoast Science Center ![Front of property](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/f67ba914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed with Sofa bed, Kitchen, Ocean View | Water view](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/00d05ebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/32ff2edb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed with Sofa bed, Kitchen, Ocean View | Living area](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/658a2b00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rye Motor Inn: An Adults-Only Apartment Hotel 0.8 km from Seacoast Science Center 9.6/10 Exceptional (87) "Clean room, friendly staff and environment. We enjoyed our stay. " CA $244 CA $313 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Portsmouth-Hotels-Rye-Motor-Inn-Swim-Shop.h48600391.Hotel-Information) ![Deluxe Apartment, 1 King Bed with Sofa bed, Kitchen, Garden Area | Private kitchen](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/ca6201ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed, Kitchen | Living area](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/37e611eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/ca2bfb70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/f3bda575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Great Island Inn 3 km from Seacoast Science Center 10/10 Exceptional (114) "Great place, wonderful neighborhood and I would stay there again." CA $236 CA $304 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Portsmouth-Hotels-Great-Island-Inn.h19249744.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/11000000/10350000/10342700/10342696/58e99d49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Double Beds](https://images.trvl-media.com/lodging/11000000/10350000/10342700/10342696/a7c42cee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10350000/10342700/10342696/33374bec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/11000000/10350000/10342700/10342696/33b37c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kittery Inn and Suites 6.3 km from Seacoast Science Center 9.2/10 Wonderful (1009) "Very nice place to stay" CA $102 CA $112 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Kittery-Hotels-Kittery-Inn-And-Suites.h10342696.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/e05bdc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/4f7aa680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/0b4312c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/be60b7a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Portsmouth 6.2 km from Seacoast Science Center 8.6/10 Excellent (1008) "Very clean and conveniently located to I95" CA $133 CA $144 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Howard-Johnson-By-Wyndham-Portsmouth.h517424.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/3ef38fa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/8d4d80bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/691e5063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/c830aaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn 4.7 km from Seacoast Science Center 8.6/10 Excellent (1000) "Great place " CA $194 CA $210 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h1553.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/93cf4954.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/b9a608d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/05a61215.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/04468f6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites By Hilton Portsmouth Downtown 5.4 km from Seacoast Science Center 9.0/10 Wonderful (10) "Great place to stay downtown. " CA $177 CA $192 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Homewood-Suites-By-Hilton-Portsmouth-Downtown.h119370959.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/77000000/76570000/76561200/76561112/52afd2e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/77000000/76570000/76561200/76561112/32c22ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/77000000/76570000/76561200/76561112/9a14e138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76570000/76561200/76561112/ebf699b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Thaxter 5.1 km from Seacoast Science Center 9.8/10 Exceptional (212) "Great location to walk to everything! Super friendly and helpful staff. Charming and well thought out services and amenities. " CA $234 CA $254 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Hotel-Thaxter.h76561112.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/b0df55fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![37-inch LCD TV with premium channels, TV](https://images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/ff6ab10e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/w3840h2554x0y4-56b09bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/w3837h2557x3y3-3e197b6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Portsmouth Downtown 5.3 km from Seacoast Science Center 9.4/10 Exceptional (1042) "Lovely place, in a great location. " CA $207 CA $224 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Portsmouth-Downtown.h8268861.Hotel-Information) ![Seasonal outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/c1712c91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/98db6c10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/ba7f270c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/6e1e8681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Port Inn and Suites Portsmouth, an Ascend Collection Hotel 5.9 km from Seacoast Science Center 8.2/10 Very good (1003) "Great & Beautiful area!" CA $129 CA $140 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information) ![Deluxe Studio Suite, 1 King Bed, Non Smoking, River View | Floor plan](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/556bc883.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![34-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/6ffc1cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Bedrooms, Non Smoking, River View](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/e7877853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/c7690844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Water Street Inn 5.4 km from Seacoast Science Center 9.8/10 Exceptional (192) "Was a great place to stay. Quiet, " CA $199 CA $217 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Kittery-Hotels-The-Water-Street-Inn.h27373163.Hotel-Information) ![54-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/04771d1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![54-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/8f0fe745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed, Ensuite (2)](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/f168e496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/94dd9ffc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sailmaker's House 4.8 km from Seacoast Science Center 9.6/10 Exceptional (357) "Lots of nearby shops. Clean comfortable bed great shower great location easy walking into town Enjoyed our stay yes would recommend for a B&B style stay. " CA $218 CA $237 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-The-Sailmakers-House.h21914111.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3840h2556x0y3-bb4935fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3836h2558x4y4-d61330d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3836h2555x4y4-eaae2626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/3b1497da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Kittery 6.7 km from Seacoast Science Center 9.2/10 Wonderful (15) "Clean room, friendly staff, convenient location." CA $182 CA $198 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Kittery-Hotels-Home2-Suites-By-Hilton-Kittery.h118242928.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/97000000/96650000/96646700/96646687/f2b18700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/97000000/96650000/96646700/96646687/d9392349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillowtop beds, minibar](https://images.trvl-media.com/lodging/97000000/96650000/96646700/96646687/9a64212f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/97000000/96650000/96646700/96646687/16685db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Davenport Inn 4.9 km from Seacoast Science Center 10/10 Exceptional (43) "Absolutely loved this place! Our room was stunning, the staff was wonderful, and had such a great selection of little snacks. I can’t wait for another opportunity to stay here! " CA $611 CA $663 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Portsmouth-Hotels-70-Court-St.h96646687.Hotel-Information) ![Fitness facility](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/fe7384b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/68b817d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/196f0181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/a0373978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Everhome Suites Portsmouth - Newington 9.3 km from Seacoast Science Center 9.6/10 Exceptional (18) "Beautiful new hotel." CA $165 CA $179 total includes taxes & fees Oct 8 - Oct 9 [](https://www.expedia.ca/Portsmouth-Hotels-Everhome-Suites-Portsmouth-Newington.h114348659.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/33000000/32550000/32545000/32544943/03b62022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightingale](https://images.trvl-media.com/lodging/33000000/32550000/32545000/32544943/8cc00966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32550000/32545000/32544943/6018c319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/33000000/32550000/32545000/32544943/a63a675c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Martin Hill Inn 5.3 km from Seacoast Science Center 9.4/10 Exceptional (128) "Have stayed here often " CA $287 CA $312 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Portsmouth-Hotels-Martin-Hill-Inn.h32544943.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/57248fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/w3994h2667x6y0-6868c150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/91278ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/db04a5b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Portsmouth Downtown/ Waterfront 5.3 km from Seacoast Science Center 9.0/10 Wonderful (1003) "Will definitely stay here again!" CA $206 CA $224 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Residence-Inn-By-Marriott-Portsmouth-Downtown-Waterfront.h3500249.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/54cd3257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/ad3e3b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/c4bb70ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Refrigerator & Microwave](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/w996h504x4y0-f5b34050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Kittery-Portsmouth 7.6 km from Seacoast Science Center 9.2/10 Wonderful (992) "Clean updated rooms and great breakfast! " CA $153 CA $167 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Kittery-Hotels-Hampton-Inn-Suites-Kittery.h29370772.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/7de77d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/40a06737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible, Bathtub (Mini Fridge/Microwave) | Living area](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3836h2556x4y4-1f1a3462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3836h2557x4y3-6b444ce8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Portsmouth Downtown 5.2 km from Seacoast Science Center 8.6/10 Excellent (125) "The location was great!" CA $195 CA $211 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/b6579a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/f13e0d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/1c349d3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/dea134f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott in Portsmouth 6.5 km from Seacoast Science Center 8.6/10 Excellent (920) "This is my favorite place to stay in the Portsmouth area. " CA $162 CA $176 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Courtyard-By-Marriott-In-Portsmouth.h42638.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/e05f87c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/f67cdc27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/6d6f97c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/ad34c3db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Portsmouth Central 8.3 km from Seacoast Science Center 8.8/10 Excellent (1000) "Staff was very friendly " CA $136 CA $148 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Portsmouth-Central.h55572.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-21&endDate=2025-10-22®ionId=6173778&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Seacoast Science Center Hotel Reviews ![Hilton Garden Inn Portsmouth Downtown](//images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/7de77d01_y.jpg) ### Hilton Garden Inn Portsmouth Downtown 10/10 Excellent "We loved the location..it was convenient and very walkable to anywhere in town..The room was spotless and comfortable " [](https://expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) ![Port Inn and Suites Portsmouth, an Ascend Collection Hotel](//images.trvl-media.com/lodging/1000000/900000/894200/894133/c1712c91_y.jpg) ### Port Inn and Suites Portsmouth, an Ascend Collection Hotel 10/10 Excellent "Great & Beautiful area!" [](https://expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information) ![The Hotel Portsmouth](//images.trvl-media.com/lodging/1000000/20000/10300/10206/1247ecd5_y.jpg) ### The Hotel Portsmouth 10/10 Excellent "Friendly, clean and a great central location" [](https://expedia.ca/Portsmouth-Hotels-The-Hotel-Portsmouth.h10206.Hotel-Information) ![Howard Johnson by Wyndham Portsmouth](//images.trvl-media.com/lodging/1000000/520000/517500/517424/e05bdc89_y.jpg) ### Howard Johnson by Wyndham Portsmouth 10/10 Excellent "So far, our stay has been very positive." [](https://expedia.ca/Portsmouth-Hotels-Howard-Johnson-By-Wyndham-Portsmouth.h517424.Hotel-Information) ![Hampton Inn & Suites Portsmouth Downtown](//images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/b0df55fb_y.jpg) ### Hampton Inn & Suites Portsmouth Downtown 10/10 Excellent "Lots of shopping and restaurants within walking distance. " [](https://expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Portsmouth-Downtown.h8268861.Hotel-Information) ![Holiday Inn Portsmouth by IHG](//images.trvl-media.com/lodging/1000000/10000/1900/1869/85d3558a_y.jpg) ### Holiday Inn Portsmouth by IHG 10/10 Excellent "Room quiet great bed. . No noisy floor air conditioner. Nice neighborhood. Great breakfast. Has indoor swimming pool. Let me check in early. Great service. 5 miles from cute town. Restaurants shops. " [](https://expedia.ca/Portsmouth-Hotels-Holiday-Inn-Portsmouth.h1869.Hotel-Information) ![AC Hotel by Marriott Portsmouth](//images.trvl-media.com/lodging/38000000/37880000/37879000/37878980/d25c1f5d_y.jpg) ### AC Hotel by Marriott Portsmouth 10/10 Excellent "Beautiful hotel. Breakfast at $22 was well worth it. Staff was very helpful. " [](https://expedia.ca/Portsmouth-Hotels-AC-Hotel-By-Marriott-Portsmouth.h37878980.Hotel-Information) ![Homewood Suites By Hilton Portsmouth Downtown](//images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/90-58587c26_y.jpg) ### Homewood Suites By Hilton Portsmouth Downtown 10/10 Excellent "Friendly and professional staff. Room is worth the price - spacious, very clean and fully furnished. We felt right at home. " [](https://expedia.ca/Portsmouth-Hotels-Homewood-Suites-By-Hilton-Portsmouth-Downtown.h119370959.Hotel-Information) ![Hotel Thaxter](//images.trvl-media.com/lodging/77000000/76570000/76561200/76561112/52afd2e9_y.jpg) ### Hotel Thaxter 10/10 Excellent "I can’t comment on the staff because their check-in just requires you to use your phone number to access the building and your room but the hotel was excellent. The rooms have no outside noise so if you’re a light sleeper, it’s the perfect spot. I got into Portsmouth long before my check-in time so I parked in a nearby garage which ended up costing the same amount that the hotel charges ($40/nt). You’re a block away from all the shops and restaurants and a short walk to Badger’s Island in Maine where you can get drinks and/or a bite to eat and a short walk to the town hall where they had a nice little farmers market Saturday morning " [](https://expedia.ca/Portsmouth-Hotels-Hotel-Thaxter.h76561112.Hotel-Information) ### Hotels near Other Rye Attractions [](https://expedia.ca/Odiorne-Point-State-Park-Hotels.0-l6110848-0.Travel-Guide-Filter-Hotels) ![Odiorne Point State Park](https://mediaim.expedia.com/destination/2/245ac55055b8907e0bf30f0da93cf61c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Odiorne Point State Park You can take time to visit Odiorne Point State Park during your travels to Rye. Wander the beautiful beaches and seaside in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6110848) [](https://expedia.ca/Fort-McClary-State-Park-Hotels.0-l6333306-0.Travel-Guide-Filter-Hotels) ![Fort McClary State Park featuring heritage elements, military items and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/94000/94723-Fort-Mcclary-State-Park.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fort McClary State Park Look out across Portsmouth Harbor from this beautifully restored coastal fortification and discover the fort’s museum and military heritage. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6333306) [](https://expedia.ca/Prescott-Park-Hotels.0-l6272804-0.Travel-Guide-Filter-Hotels) ![Prescott Park](https://mediaim.expedia.com/destination/2/b59ee1aaaee812190b2fc14e76b2e22d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Prescott Park Explore the great outdoors at Prescott Park, a lovely green space in Portsmouth. Wander the waterfront and beautiful beaches in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6272804) [](https://expedia.ca/Market-Square-Hotels.0-l6333271-0.Travel-Guide-Filter-Hotels) ![Market Square](https://mediaim.expedia.com/destination/1/7465d9d6c798b05a549a923f2bf114ed.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Market Square You can learn about the history of Portsmouth with a visit to Market Square. While in this family-friendly area, you can savor the top-notch restaurants. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6333271) [](https://expedia.ca/Fort-Stark-State-Historic-Site-Hotels.0-l6333321-0.Travel-Guide-Filter-Hotels) #### Fort Stark State Historic Site Explore the great outdoors at Fort Stark State Historic Site, a lovely green space in New Castle. Wander the beautiful beaches and seaside in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6333321) [](https://expedia.ca/Wentworth-By-The-Sea-Golf-Club-Hotels.0-l6110852-0.Travel-Guide-Filter-Hotels) #### Wentworth by the Sea Golf Club Enjoy a round of golf in Rye at Wentworth by the Sea Golf Club. Wander the beautiful beaches and seaside in the area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6110852) ## Frequently asked questions ### What's the area like around Seacoast Science Center? > Seacoast Science Center is located in a historic area of Rye known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 15 hotels and other accommodations you'll find within a mile. ### What's the best place to stay close to Seacoast Science Center? > [Rye Motor Inn: An Adults-Only Apartment Hotel](https://www.expedia.ca/Portsmouth-Hotels-Rye-Motor-Inn-Swim-Shop.h48600391.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this apartment offers private balconies and a seasonal outdoor pool. It's located just a short 0.5 mi (0.8 km) from Seacoast Science Center. Other good options within a few miles include [Hilton Garden Inn Portsmouth Downtown](https://www.expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) and [Hampton Inn & Suites Portsmouth Downtown](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Portsmouth-Downtown.h8268861.Hotel-Information). ### How many hotels can I expect to find near Seacoast Science Center? > Expedia has 15 hotels and other accommodations within a mile from Seacoast Science Center. ### If I need to cancel the hotel reservation for my stay near Seacoast Science Center, will I receive a refund? > Yes, you'll find most room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer near Seacoast Science Center. ### What can I see and do near Seacoast Science Center? > Study the collections at Strawbery Banke Museum, Kittery Historical and Naval Museum, or American Independence Museum. Market Square, Portsmouth Harbor Trail, and Portsmouth Harbor Lighthouse are monuments to see when you're exploring the area around Seacoast Science Center. You can watch performances at The Music Hall, Seacoast Repertory Theatre, and Players Ring Theatre if you're interested in local theater. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in Portsmouth](https://www.expedia.ca/4Star-Portsmouth-Hotels.s40-0-d6057414.Travel-Guide-Filter-Hotels) - [4 Star Hotels in South End](https://www.expedia.ca/4Star-South-End-Portsmouth-Hotels.s40-n905208930211381248-0.Travel-Guide-Filter-Hotels) - [Hotels near Casino Ballroom](https://www.expedia.ca/Casino-Ballroom-Hotels.0-l6333223-0.Travel-Guide-Filter-Hotels) - [Hotels near Casino Cascade Water Slide](https://www.expedia.ca/Casino-Cascade-Water-Slide-Hotels.0-l6333602-0.Travel-Guide-Filter-Hotels) - [Family Hotels in Downtown](https://www.expedia.ca/Downtown-Portsmouth-Hotels-Family-Hotel.0-n905207656638242816-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Downtown](https://www.expedia.ca/Downtown-Portsmouth-Hotels-Pet-Friendly-Hotel.0-n905207656638242816-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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