Title: The 10 Best Hotels Near Seacoast Science Center, Rye from CA $108 | Expedia.ca [Vacation Rentals in Rye](https://expedia.ca/Rye-Vacation-Rentals.d154187.Travel-Guide-VacationRentals)[Flights to Rye](https://expedia.ca/Cheap-Flights-To-Rye.d154187.Travel-Guide-Flights)[Seacoast Science Center Car Rentals](https://expedia.ca/Car-Rentals-In-Seacoast-Science-Center.d6173778.Car-Rental-Guide)[Seacoast Science Center Vacations](https://expedia.ca/Seacoast-Science-Center-Rye.d6173778.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 28 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2026-02-28&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 1 - Mar 2](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2026-03-01&endDate=2026-03-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6173778&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Seacoast Science Center hotels ![Garden](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/52db9a2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed with Sofa bed, Kitchen, Ocean View | Terrace/patio](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/01023257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/f67ba914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment, 1 King Bed with Sofa bed, Kitchen, Ocean View | Water view](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/be9bd1d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rye Motor Inn - Oceanfront, Walk to Beach [](https://www.expedia.ca/Portsmouth-Hotels-Rye-Motor-Inn-Swim-Shop.h48600391.Hotel-Information) 0.8 km from Seacoast Science Center 9.8/10 Exceptional (93 reviews) "A wonderful place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy [](https://www.expedia.ca/Portsmouth-Hotels-Rye-Motor-Inn-Swim-Shop.h48600391.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/fcba33b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker, electric kettle, toaster](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/06b5e277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, 2 Bedrooms, Kitchen, Harbour View | Living area](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/28336631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Apartment, 1 Queen Bed, Kitchen | Bathroom](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/f0881878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Great Island Inn [](https://www.expedia.ca/Portsmouth-Hotels-Great-Island-Inn.h19249744.Hotel-Information) 3 km from Seacoast Science Center 10/10 Exceptional (115 reviews) "Great place, wonderful neighborhood and I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean CA $162 CA $221 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Portsmouth-Hotels-Great-Island-Inn.h19249744.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/3a6d42f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![34-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/6ffc1cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/4531c54c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Bedrooms, Non Smoking, River View](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/28752904.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Water Street Inn [](https://www.expedia.ca/Kittery-Hotels-The-Water-Street-Inn.h27373163.Hotel-Information) 5.4 km from Seacoast Science Center 9.8/10 Exceptional (209 reviews) "Amazing place we are absolutely going back next year. The staff the accommodations, cleanliness bravo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony CA $278 CA $304 total includes taxes & fees Mar 7 - Mar 8 [](https://www.expedia.ca/Kittery-Hotels-The-Water-Street-Inn.h27373163.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/e05bdc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/defc498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/de059457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/8fe7356c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-Howard-Johnson-By-Wyndham-Portsmouth.h517424.Hotel-Information) 6.2 km from Seacoast Science Center 8.6/10 Excellent (1,003 reviews) "Quiet hotel, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristalee CA $100 CA $108 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-Howard-Johnson-By-Wyndham-Portsmouth.h517424.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/689b6164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/ceae6399.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/a90c7ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/54cd3257.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Kittery-Portsmouth [](https://www.expedia.ca/Kittery-Hotels-Hampton-Inn-Suites-Kittery.h29370772.Hotel-Information) 7.6 km from Seacoast Science Center 9.2/10 Wonderful (1,001 reviews) "Excellent stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) angel CA $144 CA $157 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Kittery-Hotels-Hampton-Inn-Suites-Kittery.h29370772.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/c830aaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/75daabab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/b977596f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/691e5063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h1553.Hotel-Information) 4.7 km from Seacoast Science Center 8.6/10 Excellent (1,000 reviews) "Friendly staff and clean comfortable rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) christian CA $169 CA $184 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Portsmouth-Hotels-Quality-Inn.h1553.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/e27257a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3837h2557x3y3-34dcadbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3837h2557x3y3-f8960a09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/w3840h2557x0y3-0e30d920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Portsmouth Downtown [](https://www.expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) 5.2 km from Seacoast Science Center 8.4/10 Very good (255 reviews) "Great staff and great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $136 CA $147 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) ![1 bedroom, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/0b6ef913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/f6cb6e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/8091c40f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/194e19d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sailmaker's House [](https://www.expedia.ca/Portsmouth-Hotels-The-Sailmakers-House.h21914111.Hotel-Information) 4.8 km from Seacoast Science Center 9.6/10 Exceptional (374 reviews) "beautiful and historic architecture! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) RICHARD PHILLIPS CA $202 CA $220 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-The-Sailmakers-House.h21914111.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/bf5361b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/a038b6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/0240f672.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370959/93cf4954.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites By Hilton Portsmouth Downtown [](https://www.expedia.ca/Portsmouth-Hotels-Homewood-Suites-By-Hilton-Portsmouth-Downtown.h119370959.Hotel-Information) 5.4 km from Seacoast Science Center 9.0/10 Wonderful (64 reviews) "Room was spotless and the staff was very courteous." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randall CA $161 CA $175 total includes taxes & fees Mar 11 - Mar 12 [](https://www.expedia.ca/Portsmouth-Hotels-Homewood-Suites-By-Hilton-Portsmouth-Downtown.h119370959.Hotel-Information) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/e343f353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/e2dbf3e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/6534cb01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/bee99493.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Portsmouth Central [](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Portsmouth-Central.h55572.Hotel-Information) 8.2 km from Seacoast Science Center 8.8/10 Excellent (1,001 reviews) "The experience in a whole was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha CA $144 CA $157 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Portsmouth-Central.h55572.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6800/6779/ef15456a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6800/6779/abe7c2c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/6800/6779/baae6819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/1000000/10000/6800/6779/244620c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn by Marriott Portsmouth-Seacoast [](https://www.expedia.ca/Portsmouth-Hotels-Fairfield-Inn-By-Marriott-Portsmouth-Seacoast.h6779.Hotel-Information) 6 km from Seacoast Science Center 8.6/10 Excellent (1,000 reviews) "Friendly and helpful staff, clean room and lovely breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Heather CA $138 CA $149 total includes taxes & fees Mar 16 - Mar 17 [](https://www.expedia.ca/Portsmouth-Hotels-Fairfield-Inn-By-Marriott-Portsmouth-Seacoast.h6779.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/6e1e8681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/43e2fe11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/f3058983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/69c87334.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Port Inn and Suites Portsmouth, an Ascend Collection Hotel [](https://www.expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information) 5.9 km from Seacoast Science Center 8.0/10 Very good (1,000 reviews) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Max CA $122 CA $132 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/10300/10206/ad86cd83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/10300/10206/1247ecd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/10300/10206/cca813b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/20000/10300/10206/75687f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hotel Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-The-Hotel-Portsmouth.h10206.Hotel-Information) 5 km from Seacoast Science Center 9.4/10 Exceptional (1,005 reviews) "This was second time we stayed at this hotel and we enjoyed our stay again! We like to stay at historical buildings and we just love the hotel’s architecture and atmosphere. The hotel staffs were friendly and polite and everything was great. We love to come back again soon!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $166 CA $180 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-The-Hotel-Portsmouth.h10206.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/e0ec926f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/1c3d8d0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/592ae444.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348659/a802a7e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Everhome Suites Portsmouth - Newington [](https://www.expedia.ca/Portsmouth-Hotels-Everhome-Suites-Portsmouth-Newington.h114348659.Hotel-Information) 9.4 km from Seacoast Science Center 9.2/10 Wonderful (82 reviews) "Yes, staff was exceptional, room was one of the nicest i have seen, and before I retired I travelled for work, so I has a lot of hotel stays." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $135 CA $146 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Portsmouth-Hotels-Everhome-Suites-Portsmouth-Newington.h114348659.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/1a7014a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/91278ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/57248fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/ad1b9718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Portsmouth Downtown/ Waterfront [](https://www.expedia.ca/Portsmouth-Hotels-Residence-Inn-By-Marriott-Portsmouth-Downtown-Waterfront.h3500249.Hotel-Information) 5.3 km from Seacoast Science Center 9.0/10 Wonderful (1,001 reviews) "Will definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary CA $174 CA $188 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-Residence-Inn-By-Marriott-Portsmouth-Downtown-Waterfront.h3500249.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/38000000/37880000/37879000/37878980/w4000h2662x0y0-b4f57fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/38000000/37880000/37879000/37878980/7939b65e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/38000000/37880000/37879000/37878980/d6c5c164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/38000000/37880000/37879000/37878980/d25c1f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel by Marriott Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-AC-Hotel-By-Marriott-Portsmouth.h37878980.Hotel-Information) 5.5 km from Seacoast Science Center 9.2/10 Wonderful (985 reviews) "Staff were friendly and helpful. Hotel was clean and welcoming" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean CA $184 CA $237 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Portsmouth-Hotels-AC-Hotel-By-Marriott-Portsmouth.h37878980.Hotel-Information) ![Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/7000000/6860000/6850800/6850709/036e7fe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6860000/6850800/6850709/831bed1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast (USD 10 per person)](https://images.trvl-media.com/lodging/7000000/6860000/6850800/6850709/821cfb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6860000/6850800/6850709/fed72e4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Portsmouth Hotel & Suites [](https://www.expedia.ca/Portsmouth-Hotels-Best-Western-Plus-Portsmouth-Hotel-Suites.h6850709.Hotel-Information) 6.2 km from Seacoast Science Center 7.6/10 Good (1,001 reviews) "Room was clean and comfortable. A little dated but convenient when traveling " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Debra CA $103 CA $112 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Portsmouth-Hotels-Best-Western-Plus-Portsmouth-Hotel-Suites.h6850709.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/1c349d3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/dbc4f33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch flat-screen TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/569bd45d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42700/42638/f8280190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott in Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-Courtyard-By-Marriott-In-Portsmouth.h42638.Hotel-Information) 6.5 km from Seacoast Science Center 8.6/10 Excellent (945 reviews) "This is my favorite place to stay in the Portsmouth area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gwendolyne CA $150 CA $162 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Portsmouth-Hotels-Courtyard-By-Marriott-In-Portsmouth.h42638.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/12000000/11790000/11781700/11781669/6f5b43eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11790000/11781700/11781669/27f394da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/12000000/11790000/11781700/11781669/febc21df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11790000/11781700/11781669/dcaf113c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Bow Hotel [](https://www.expedia.ca/Portsmouth-Hotels-Ale-House-Inn.h11781669.Hotel-Information) 5 km from Seacoast Science Center 8.6/10 Excellent (511 reviews) "Room was clean enough, location was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joshua CA $134 CA $146 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-Ale-House-Inn.h11781669.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/6000/5911/90916c2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/6000/5911/w4000h2662x0y0-083d694d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6000/5911/92cc7e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/6000/5911/5f4a933c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Portsmouth Harborside Hotel [](https://www.expedia.ca/Portsmouth-Hotels-Sheraton-Portsmouth-Harborside-Hotel.h5911.Hotel-Information) 5.4 km from Seacoast Science Center 8.6/10 Excellent (1,001 reviews) "Fun" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $219 CA $238 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Portsmouth-Hotels-Sheraton-Portsmouth-Harborside-Hotel.h5911.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-14&endDate=2026-03-15®ionId=6173778&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Seacoast Science Center | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | -------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Garden](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/52db9a2b.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Rye Motor Inn - Oceanfront, Walk to Beach | 3.0 star property | 9.8Exceptional93 reviews | View | | | | | | | ![Front of property](https://images.trvl-media.com/lodging/20000000/19250000/19249800/19249744/fcba33b4.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Great Island Inn | 3.5 star property | 10.0Exceptional115 reviews | View | | | | | | | ![Garden](https://images.trvl-media.com/lodging/28000000/27380000/27373200/27373163/3a6d42f5.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Water Street Inn | 3.5 star property | 9.8Exceptional209 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/e05bdc89.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Howard Johnson by Wyndham Portsmouth | 2.0 star property | 8.6Excellent1,003 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/30000000/29380000/29370800/29370772/689b6164.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Kittery-Portsmouth | 2.5 star property | 9.2Wonderful1,001 reviews | View | | | | | | ## Top Seacoast Science Center Hotel Reviews ![The Hotel Portsmouth](https://images.trvl-media.com/lodging/1000000/20000/10300/10206/1247ecd5_y.jpg) ### The Hotel Portsmouth 10/10 Excellent "Amazing location with so many great destinations within walking distance. Unique environment with a great breakfast and friendly staff." [](https://expedia.ca/Portsmouth-Hotels-The-Hotel-Portsmouth.h10206.Hotel-Information) ![Amazing harbor/ocean views of Pepperrell Cove](https://images.trvl-media.com/lodging/93000000/92710000/92706700/92706652/w926h683x49y0-4101698d_y.jpg) ### Amazing harbor/ocean views of Pepperrell Cove 10/10 Excellent "Todd responded quickly to questions we had regarding the heat during our February stay. The house is well appointed and beds are comfy. Located down the lane form a busy street we enjoyed the quiet and fireplace as snow whirled and piled up outside." [](https://expedia.ca/Kittery-Point-Hotels-Amazing-Harborocean-Views-Of-Pepperrell-Cove.h92706652.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/10000/1600/1553/3ef38fa1_y.jpg) ### Quality Inn 10/10 Excellent "Staff were very friendly, rooms were in beautiful shape and the amenities and breakfast were awesome. Will be back for sure!" [](https://expedia.ca/Portsmouth-Hotels-Quality-Inn.h1553.Hotel-Information) ![Port Inn and Suites Portsmouth, an Ascend Collection Hotel](https://images.trvl-media.com/lodging/1000000/900000/894200/894133/6e1e8681_y.jpg) ### Port Inn and Suites Portsmouth, an Ascend Collection Hotel 10/10 Excellent "Great location! Great breakfast!" [](https://expedia.ca/Portsmouth-Hotels-Port-Inn-And-Suites-Portsmouth.h894133.Hotel-Information) ![Sheraton Portsmouth Harborside Hotel](https://images.trvl-media.com/lodging/1000000/10000/6000/5911/92cc7e79_y.jpg) ### Sheraton Portsmouth Harborside Hotel 10/10 Excellent "The staff were pleasant. The room was perfect in every way." [](https://expedia.ca/Portsmouth-Hotels-Sheraton-Portsmouth-Harborside-Hotel.h5911.Hotel-Information) ![Hampton Inn & Suites Portsmouth Downtown](https://images.trvl-media.com/lodging/9000000/8270000/8268900/8268861/b0df55fb_y.jpg) ### Hampton Inn & Suites Portsmouth Downtown 10/10 Excellent "Friendly staff, clean room, great common area, delicious breakfast (even GF options). " [](https://expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Portsmouth-Downtown.h8268861.Hotel-Information) ![The Sailmaker's House](https://images.trvl-media.com/lodging/22000000/21920000/21914200/21914111/04771d1a_y.jpg) ### The Sailmaker's House 10/10 Excellent " Very comfortable stay!" [](https://expedia.ca/Portsmouth-Hotels-The-Sailmakers-House.h21914111.Hotel-Information) ![Hilton Garden Inn Portsmouth Downtown](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/7de77d01_y.jpg) ### Hilton Garden Inn Portsmouth Downtown 10/10 Excellent "Nice clean room. Loved the big roomy shower!" [](https://expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) ![Rye Motor Inn: An Adults-Only Apartment Hotel](https://images.trvl-media.com/lodging/49000000/48610000/48600400/48600391/f67ba914_y.jpg) ### Rye Motor Inn: An Adults-Only Apartment Hotel 10/10 Excellent "very clean, cozy and friendly service. " [](https://expedia.ca/Portsmouth-Hotels-Rye-Motor-Inn-Swim-Shop.h48600391.Hotel-Information) ## Hotels near other Seacoast Science Center attractions ![Blue, green, brown + yellow = nature Beautiful and is peaceful #sea #nature #flower](https://images.trvl-media.com/place/154187/894966d7-0ca9-49bf-bc76-3f8275f25734.jpg) Photo by Ana Lei ### Odiorne Point State Park You can take time to visit Odiorne Point State Park during your travels to Rye. Wander the beautiful beaches and seaside in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6110848) ![Portsmouth_FortStarkStateHistoricSite_6333321_05](https://images.trvl-media.com/place/6333321/8c4ff3dc-3508-4c55-98a9-2caa4334964e.jpg) ### Fort Stark State Historic Site Explore the great outdoors at Fort Stark State Historic Site, a lovely green space in New Castle. Wander the beautiful beaches and seaside in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6333321) ![Portsmouth_Portsmouth_PortsmouthHarborLighthouse__01](https://images.trvl-media.com/place/553248621532667550/4b016161-481f-4507-a107-9a7617801425.jpg) ### Portsmouth Harbor Lighthouse 5.0/5 (8 reviews) You can learn about the history of New Castle with a stop at Portsmouth Harbor Lighthouse. Stroll along the waterfront in this family-friendly area, or check out its top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532667550) ### Wentworth by the Sea Golf Club Enjoy a round of golf in Rye at Wentworth by the Sea Golf Club. Wander the beautiful beaches and seaside in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6110852) ### Fort Constitution Historical Site You can learn about the history of New Castle with a trip to Fort Constitution Historical Site. Wander the waterfront and beautiful beaches in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6110838) ### American Independence Museum You can study the exhibits at American Independence Museum, a museum with a story of its own, during your travels to New Castle. Wander the waterfront and beautiful beaches in the area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621533117308) ## Frequently asked questions ### What's the area like around Seacoast Science Center? ### What's the best place to stay close to Seacoast Science Center? ### How many hotels can I expect to find near Seacoast Science Center? ### If I need to cancel the hotel reservation for my stay near Seacoast Science Center, will I receive a refund? ### What can I see and do near Seacoast Science Center? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in Portsmouth ](https://www.expedia.ca/4Star-Portsmouth-Hotels.s40-0-d6057414.Travel-Guide-Filter-Hotels) - [4 Star Hotels in South End ](https://www.expedia.ca/4Star-South-End-Portsmouth-Hotels.s40-n905208930211381248-0.Travel-Guide-Filter-Hotels) - [Hotels near Casino Ballroom ](https://www.expedia.ca/Casino-Ballroom-Hotels.0-l6333223-0.Travel-Guide-Filter-Hotels) - [Hotels near Casino Cascade Water Slide ](https://www.expedia.ca/Casino-Cascade-Water-Slide-Hotels.0-l6333602-0.Travel-Guide-Filter-Hotels) - 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