Use Expedia and let us help you arrange a flight to Portsmouth, NH (PSM-Portsmouth Intl.) airport or Sanford, ME (SFM-Sanford Seacoast Regional) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are important when you plan a vacation, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Portsmouth has to offer. During your visit, you might want to enjoy the beaches and shopping which Portsmouth is known for.