Santo Domingo Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Santo Domingo vacation deals

Price found within the past 48 hours. Click for updated prices.
  • Jan 8 - Jan 12

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen Airport
    4 nights
    4.0 star property
    8.6/10 - Excellent (1,813 reviews)
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 2 stops
    CA $1,726
    CA $1,258
    per traveller
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • Dec 19 - Dec 23

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    4 nights
    4.0 star property
    9.2/10 - Wonderful (1,002 reviews)
    "Good breakfast Everything was just OK"
    Reviewed November 5, 2026
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 1 stop
    CA $3,464
    CA $1,929
    per traveller
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • Dec 19 - Dec 23

    Megapolis Hotel Panamá + Flight

    San Francisco
    4 nights
    4.5 star property
    8.6/10 - Excellent (1,839 reviews)
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 1 stop
    CA $2,751
    CA $1,630
    per traveller
    found 1 day ago
    Megapolis Hotel Panamá
  • Dec 28 - Jan 3

    Casa Mallet by Wynwood House + Flight

    Casco Viejo
    6 nights
    3.5 star property
    9.8/10 - Exceptional (30 reviews)
    "I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect. The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us. I would stay here again in a heart beat. It’s a must stay!"
    Reviewed September 16, 2026
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 1 stop
    Save 100% on your flight
    CA $11,903
    CA $8,259
    per traveller
    found 1 day ago
    Casa Mallet by Wynwood House
  • Jan 8 - Jan 12

    Sofitel Legend Casco Viejo, Panama City + Flight

    Casco Viejo
    4 nights
    5.0 star property
    9.8/10 - Exceptional (771 reviews)
    "Magnificent property. Location. Staff. Quality of all, staff, facilities, best place in Panama!"
    Reviewed October 30, 2026
    Roundtrip • Toronto (YTO) - Panama City (PTY)
    YYZ - PTY • 1 stop PTY - YYZ • 2 stops
    CA $3,020
    CA $2,284
    per traveller
    found 1 day ago
    Sofitel Legend Casco Viejo, Panama City

Santo Domingo Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Santo Domingo vacation package cost?

Offering great value package deals from CA $1,258 on Expedia, you'll be surprised at how little a vacation to Santo Domingo costs! Expedia's packages simplify travel planning and maximize your savings.

What are the cheapest months to go to Santo Domingo?

You can typically find lower rates and greater availability in August, September and October. Take a look at our cheap Santo Domingo vacation packages and you could get some great off-season deals.

How many days is enough for Santo Domingo?

The ideal length of your Santo Domingo vacation depends on what you'd like to do. Generally, a handful of days to a week will give you plenty of time to tick off all the main attractions and explore some hidden spots along the way.

How to find the best Santo Domingo package deals?

Begin your search for a Santo Domingo package deal by entering your destination and preferred travel dates under our "Packages" tab. Then apply a few filters, like "Property type" and "Popular locations," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the ideal Santo Domingo package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santo Domingo getaway off to a flying start.

Is it cheaper to book a Santo Domingo vacation as a package?

You can enjoy significant savings on your Santo Domingo break by booking a tailored vacation package. Check the "Package" heading, then enter your travel dates and destination to view the best hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.

When to book a vacation package to Santo Domingo?

If you've got your Santo Domingo travel dates locked in, book early to snap up some awesome deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are ideal for impromptu escapes.

How to plan a trip to Santo Domingo?

  1. Choose the best time to travel: Your schedule, favourite season and the type of weather you enjoy can all impact your decision on when to visit Santo Domingo.
  2. Figure out your budget: Ensure you have enough money to pay for everything from transportation and meals to experiences and flights. Your hotel will probably be the biggest expense during your trip to Santo Domingo.
  3. Set the duration of your trip: Start by listing all the attractions you'd like to experience in Santo Domingo. Then, estimate how long you'll need for each, including any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a personalized Santo Domingo vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.