Santa Clara Vacation Rentals from CA $58: Short-Term Rentals for 2026

Q: What's the top vacation rental in Santa Clara?

La casa de Matias : You might want to consider this vacation rental near Santa Clara, which offers a garden and free WiFi to help you feel comfortable in your new surroundings.

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Santa Clara vacation rentals

1. la casa de Matias

Volcán

CA $58 total

includes taxes & fees

Sep 14 - Sep 15

2. Volcano View Cottage

Volcán

John E.

CA $125 total

includes taxes & fees

Sep 5 - Sep 6

3. La Casa Donde el Tiempo Va Más Despacio

Volcán

CA $107 total

includes taxes & fees

Sep 2 - Sep 3

4. matias' house

Volcán

CA $109 total

includes taxes & fees

Sep 2 - Sep 3

5. Cool Mountain Escape | Family Fun | Volcán

Nueva California

CA $78 total

includes taxes & fees

Sep 2 - Sep 3

6. Cabañas Mountain View, near to the national park Volcan Baru

Volcán

Paquita B.

CA $141 total

includes taxes & fees

Sep 2 - Sep 3

7. Volcano breezes

Volcán

CA $103 total

includes taxes & fees

Sep 2 - Sep 3

8. Cabañas Mountain View

Volcán

CA $180 total

includes taxes & fees

Sep 3 - Sep 4

View all properties

Find vacation rentals that suit your style

Apartments

Cabins

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top Santa Clara Hotel Reviews

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

10/10 Excellent

"Me gusto todo. La habitación con una vista increíble, el restaurante muy bien atendido y buena cómida. La piscina climatizada es genial"

Risco de Hugo

10/10 Excellent

"We thoroughly enjoyed our stay at the Risco de Hugo property. The lodgings were beautiful, everything was super clean, the views were amazing, and the general area was peaceful and serene. One of the owners, Jared, was super friendly and really went above and beyond to tell us about the area, help us with the fire pit, coordinate parking with newcomers, etc. Best stay of our month-long trip - we highly recommend!"

Ecoresort: We are Panamas leading honey producer and butterfly exhibit.

10/10 Excellent

"This was a wonderful experience and stunning property to stay on! Emily was incredibly helpful - I arrived MUCH later than expected due to delays with my flight and bus, but Emily was there to help. She also made sure I had some snacks for the morning, as I had had an early start before breakfast would be ready. All the staff was wonderful! The casita was perfect, and I loved cooking on the stove on the outside porch!! Would love to return in the future :)"

Volcano View Cottage

8/10 Good

"This was no fault of the host, but Waze took us past the point and was telling us to drive up a heavy gravel construction road. YIKES! But once we located the right place, check in was smooth. The room was not thoroughly clean as there was an obvious spill under the couch and a small black wooly caterpillar, there was also a Tupperware bowl that had mold growing in it. We washed all dishes before use. Addtionally, the mattress covered had a deep stain that was visible through the fitted sheet. The best part of the property is the location is within walking distance to the heart of downtown Boquete. But the views from the balcony are not good."

Wild on the Farm, Boquete Cloud Forest Lodge

10/10 Excellent

"Leon was very communicative throughout the booking. We STRONGLY recommend meeting Leon in the town for transportation or escort up to the lodge for initial arrival. It is a very steep climb. The path gets smaller as you go higher. There are no signs letting you know if you are on the right track. Our navigation told us we had arrived when we still had further to go. We rented a 4X4 in Panama City specifically for this booking. DO NOT UNDERESTIMATE the climb up to the location. It is very difficult for someone not familiar with the area."

Find out more about Santa Clara

Everything you need to know about Santa Clara vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Clara vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Clara vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Clara vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Clara. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Clara vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Clara vacation rentals we have selected for you start as low as CA $58 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Clara rentals

At Expedia, we put the best Santa Clara vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Clara rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Clara vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Clara. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Lodging

Hotel Dos Rios

Frequently asked questions

Are there vacation rentals in Santa Clara?

Yes, we offer vacation rentals close to well known points of interest in Santa Clara, or you can choose a secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Clara?

La casa de Matias: You might want to consider this vacation rental near Santa Clara, which offers a garden and free WiFi to help you feel comfortable in your new surroundings.

What can I see and do in Santa Clara?

While you're exploring the area, Área Silvestre Protegida Lagunas de Volcán and Wilson Botanical Garden are a couple of picturesque spots to get outside and enjoy nature. La Amistad International Park and The Quetzales Trail are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Clara?

Vacation rentals are privately owned properties you can stay in for a few weeks or just a few days in Santa Clara. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have all the conveniences of home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family trip.

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Santa Clara vacation rentals

1. la casa de Matias

2. Volcano View Cottage

3. La Casa Donde el Tiempo Va Más Despacio

4. matias' house

5. Cool Mountain Escape | Family Fun | Volcán

6. Cabañas Mountain View, near to the national park Volcan Baru

7. Volcano breezes

8. Cabañas Mountain View

9. Cozy Mountain View House - Ayala's House View

10. Casa Bajareque | Tu escape en Cerro Punta

11. Cabin in Cerro Punta 6BR, Fireplace, Hiking

Find vacation rentals that suit your style

Top Santa Clara Hotel Reviews

Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals

Los Brezos Boutique Hotel

Risco de Hugo

Hotel Finca Lerida

Ecoresort: We are Panamas leading honey producer and butterfly exhibit.

Volcano View Cottage

Wild on the Farm, Boquete Cloud Forest Lodge

Hostal Victoria Volcán Chiriquí S. A.

Find out more about Santa Clara

Explore a world of travel with Expedia

Frequently asked questions

Expedia's Latest Trends

Go further with the Expedia app