A rugged desert landscape with prominent red rock formations and sparse green vegetation.

San Luis Vacation Rentals

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Our top choices for San Luis vacation rentals

Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.

Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.
San Luis
10.0 out of 10, Exceptional, (3 reviews)
"I had a great stay! The home was very nice, clean, and quiet—just what I was looking for. Everything was well-kept and comfortable, making it easy to relax. The neighborhood felt peaceful and safe, and I really appreciated how tidy the space was. I would definitely stay here again and recommend it to anyone looking for a calm and pleasant place to stay."
United States
Alexandra C.
The price is CA $177
CA $248 total
includes taxes & fees
Jul 15 - Jul 16
Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.

Cozy 1-bedroom furnished studio in peaceful San Luis, AZ.

Cozy 1-bedroom furnished studio in peaceful San Luis, AZ.
San Luis
The price is CA $99
CA $201 total
includes taxes & fees
Jul 15 - Jul 16
Cozy 1-bedroom furnished studio in peaceful San Luis, AZ.

Queen Bed|Nsmk|Yuma AZ

Queen Bed|Nsmk|Yuma AZ
Yuma Townsite
10.0 out of 10, Exceptional, (69 reviews)
"Memorable stay, everything was just right for a family getaway!"
United States
Anonymous traveller
The price is CA $116
CA $147 total
includes taxes & fees
Jul 15 - Jul 16
Queen Bed|Nsmk|Yuma AZ

Yuma AZ|Relaxing King Bed

Yuma AZ|Relaxing King Bed
Yuma AZ
10.0 out of 10, Exceptional, (97 reviews)
"Great spot, loved exploring nearby parks!"
United States
Anonymous traveller
The price is CA $100
CA $121 total
includes taxes & fees
Jul 20 - Jul 21
Yuma AZ|Relaxing King Bed

Yuma AZ|Cozy Queen Bed

Yuma AZ|Cozy Queen Bed
Yuma AZ
10.0 out of 10, Exceptional, (95 reviews)
"Good value for our group, and the location made it easy to explore!"
United States
Anonymous traveller
The price is CA $100
CA $121 total
includes taxes & fees
Jul 15 - Jul 16
Yuma AZ|Cozy Queen Bed

Yuma AZ|King Bed|Non-Smoking

Yuma AZ|King Bed|Non-Smoking
Yuma Townsite
10.0 out of 10, Exceptional, (68 reviews)
"Great location, perfect for my meetings and exploring the area!"
United States
Anonymous traveller
The price is CA $127
CA $159 total
includes taxes & fees
Jul 15 - Jul 16
Yuma AZ|King Bed|Non-Smoking

Yuma AZ|Deluxe King Bed|Non smoking

Yuma AZ|Deluxe King Bed|Non smoking
Yuma Townsite
10.0 out of 10, Exceptional, (60 reviews)
"A superb stay with a good breakfast. The staff were wonderful and made the experience great."
United States
Anonymous traveller
The price is CA $127
CA $159 total
includes taxes & fees
Jul 15 - Jul 16
Yuma AZ|Deluxe King Bed|Non smoking

Yuma AZ| Relaxing 2 Queen Bed

Yuma AZ| Relaxing 2 Queen Bed
Yuma AZ
10.0 out of 10, Exceptional, (108 reviews)
"Really relaxing atmosphere, felt very peaceful during my stay."
United States
Anonymous traveller
The price is CA $110
CA $132 total
includes taxes & fees
Jul 18 - Jul 19
Yuma AZ| Relaxing 2 Queen Bed

2 Queen Beds|Nsmk|Yuma AZ

2 Queen Beds|Nsmk|Yuma AZ
Yuma Townsite
10.0 out of 10, Exceptional, (68 reviews)
"Relaxing stay with a great breakfast! Everything was perfect!"
United States
Anonymous traveller
The price is CA $137
CA $171 total
includes taxes & fees
Jul 15 - Jul 16
2 Queen Beds|Nsmk|Yuma AZ

Cozy Executive Suite|Nsmk|Yuma AZ

Cozy Executive Suite|Nsmk|Yuma AZ
Yuma Townsite
10.0 out of 10, Exceptional, (60 reviews)
"A serene spot, perfect for a peaceful getaway, lovely grounds too!"
United States
Anonymous traveller
The price is CA $170
CA $210 total
includes taxes & fees
Jul 15 - Jul 16
Cozy Executive Suite|Nsmk|Yuma AZ

1 King&1 Queen Suite|Nsmk

1 King&1 Queen Suite|Nsmk
Yuma Townsite
10.0 out of 10, Exceptional, (69 reviews)
"Fantastic location! Really relaxing stay, felt like a mini getaway."
United States
Anonymous traveller
The price is CA $202
CA $250 total
includes taxes & fees
Jul 15 - Jul 16
1 King&1 Queen Suite|Nsmk

Poolhouse Retreat / Outdoor Oasis & Pets Welcome

Poolhouse Retreat / Outdoor Oasis & Pets Welcome
Yuma
10.0 out of 10, Exceptional, (2 reviews)
"This one bedroom guest house was a great over night stop on our way to Sedona. It was clean and well stocked, loved the Spanish decor, had a pool, big yard with BBQ, a great vibe. It looks like we shared the back yard and pool with the main house, but nobody ever came out, we could only hear them in the morning. An added bonus was the bidet, every house should have one these, we ordered three for our home as a result of staying here, lol!"
United States
Kimberly C.
The price is CA $126
CA $278 total
includes taxes & fees
Jul 23 - Jul 24
Poolhouse Retreat / Outdoor Oasis & Pets Welcome

One story fully furnished townhouse

One story fully furnished townhouse
Yuma
9.4 out of 10, Exceptional, (63 reviews)
"Great place clean, comfortable, quiet"
United States
Derek S.
The price is CA $134
CA $305 total
includes taxes & fees
Jul 15 - Jul 16
One story fully furnished townhouse

Guest House in the outskirts, Ranch living

Guest House in the outskirts, Ranch living
Somerton
8.4 out of 10, Very good, (7 reviews)
"There was a nice big yard out front. Host was friendly and answered questions promptly."
United States
Karen T.
The price is CA $102
CA $137 total
includes taxes & fees
Jul 17 - Jul 18
Guest House in the outskirts, Ranch living

Tranquil 3-bedroom house with AC in charming Yuma

Tranquil 3-bedroom house with AC in charming Yuma
Yuma
9.8 out of 10, Exceptional, (8 reviews)
"It was a charming place to stay. "
United States
Shannon P.
The price is CA $134
CA $339 total
includes taxes & fees
Jul 16 - Jul 17
Tranquil 3-bedroom house with AC in charming Yuma

Yuma Townhouse - Centrally Located!

Yuma Townhouse - Centrally Located!
Yuma
10.0 out of 10, Exceptional, (91 reviews)
"This was a great spot. Karen was so helpful and the townhouse was perfect."
United States
Christy P.
The price is CA $159
CA $333 total
includes taxes & fees
Aug 13 - Aug 14
Yuma Townhouse - Centrally Located!

New Modern home w/RV access and Garage Access.

New Modern home w/RV access and Garage Access.
Yuma
10.0 out of 10, Exceptional, (13 reviews)
"Super property, great communication, had everything we needed for our family visit to Yuma. Very impressed overall and would recommend and visit again."
United States
Michele P.
The price is CA $198
CA $440 total
includes taxes & fees
Jul 16 - Jul 17
New Modern home w/RV access and Garage Access.

The Hillside Hacienda located in the heart of Yuma. Hospital Nearby.

The Hillside Hacienda located in the heart of Yuma. Hospital Nearby.
Yuma
9.6 out of 10, Exceptional, (5 reviews)
"A clean, functional place to stay in a quiet central neighborhood that was great for evening walks. The host answered our minor questions promptly.I highly recommend for stays in Yuma."
Canada
Jude T.
The price is CA $154
CA $456 total
includes taxes & fees
Jul 20 - Jul 21
The Hillside Hacienda located in the heart of Yuma. Hospital Nearby.

Modern Desert Oasis Studio in Historic Downtown Yuma

Modern Desert Oasis Studio in Historic Downtown Yuma
Downtown Yuma
10.0 out of 10, Exceptional, (14 reviews)
"Very clean snd comfortable. Great location. "
United States
Mark S.
The price is CA $85
CA $216 total
includes taxes & fees
Jul 23 - Jul 24
Modern Desert Oasis Studio in Historic Downtown Yuma

Private 1BR Guesthouse Retreat w/ Courtyard & Pool

Private 1BR Guesthouse Retreat w/ Courtyard & Pool
Yuma
The price is CA $126
CA $320 total
includes taxes & fees
Jul 15 - Jul 16
Private 1BR Guesthouse Retreat w/ Courtyard & Pool
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Luis Hotel Reviews

Find out more about San Luis

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with San Luis. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in San Luis?

Yes, we give you a choice of vacation rentals near popular local attractions in San Luis, or you can select a more secluded option if you're looking for relaxation. San Luis is known for its parks.

What's the top vacation rental in San Luis?

One story fully furnished townhouse : Visitors like this San Luis vacation home rental. It is located on a river and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Kick off your shoes and enjoy yourself with a private yard and a hot tub.

How many vacation rentals are there in San Luis?

Choose from 4 Expedia vacation rentals in San Luis for a memorable vacation.

What can I see and do in San Luis?

Explore the area and family-friendly sights such as Saihati Camel Farm, or get out into nature at a spot like Colorado River. In the larger area, you’ll find San Luis Lakes State Park and Garita Entrance to Mexico.

What are vacation rentals like in San Luis?

Vacation rentals are privately owned properties you can book for a couple days or more in San Luis. Vacation rentals provide amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for family gatherings.