
San Luis Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to CA $1,096 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Your San Luis Vacation
Take away the hard part of planning your next exciting adventure with a San Luis vacation package. Whether you've come for its cuisine, history, art or something else, you'll find countless exciting experiences to delve into. Wondering what to see or do first during your trip to San Luis? Head for famous attractions like Cocopah Museum. Stop daydreaming and start adventuring. Check out the many options on Expedia today and finally put your San Luis vacation plans in motion!
San Luis Hotel Deals

Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.
San Luis
The price is CA $172 per night from Sep 11 to Sep 12
CA $172
CA $241 total
Sep 11 - Sep 12
includes taxes & fees

La Fuente Inn & Suites
1513 E 16th St, Yuma, AZ
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from Sep 2 to Sep 3
CA $135
CA $149 total
Sep 2 - Sep 3
includes taxes & fees
9.2/10 Wonderful! (1,996 reviews)
Very Happy
"This property was very nice. It was well kept and lots of greenery. The room was nice too. I had a King bed, Sofa bed with a coffee table, a desk, a mircowave and a frig. The AC was nice and cold too and included a ceiling fan. Everythimg about the room made me want to come back. In the morning, ..."
Reviewed on Aug. 25, 2025

Quality Inn & Suites Yuma
1691 S Riley Ave, Yuma, AZ
Fully refundableReserve now, pay when you stay
The price is CA $81 per night from Sep 6 to Sep 7
CA $81
CA $89 total
Sep 6 - Sep 7
includes taxes & fees
8/10 Very Good! (1,005 reviews)
"Quick check in and quiet"
Reviewed on Aug. 24, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Other vacations you might like
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.