Kearny Mesa

San Diego

A courtyard with palm trees, a fountain, and a flag.
A large building with a dome and arched entrance, surrounded by palm trees and a reflecting pool.

Stay near popular Kearny Mesa attractions

The Comedy Palace

You can make plans for a show at The Comedy Palace during your trip to San Diego. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Things to do

San Diego City Lights Night Tour

San Diego City Lights Night Tour

CA $60
per adult
94% of travellers recommend
San Diego City Lights Night Tour
Learn to Stand Up Paddle Board in La Jolla

Learn to Stand Up Paddle Board in La Jolla

CA $49
per traveller
Learn to Stand Up Paddle Board in La Jolla
San Diego Best of the Bay Harbor Tour

City Cruises San Diego: Best of the Bay Harbor Tour

CA $43
per adult
90% of travellers recommend
City Cruises San Diego: Best of the Bay Harbor Tour
See all activities in San Diego

Kearny Mesa Hotel Deals

Hilton Garden Inn San Diego Mission Valley Stadium

Hilton Garden Inn San Diego Mission Valley Stadium

3 out of 5
3805 Murphy Canyon Rd San Diego CA
The price is CA $169 per night from Oct 26 to Oct 27
CA $169
CA $194 total
Oct 26 - Oct 27
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8/10 Very good! (1,007 reviews)
"The continental breakfast was very disappointing. I arrived at Verda (restaurant) at 8:30 am, they only offered, coffee, juice, pastries, oatmeal, fruit, cereal and hard boiled eggs for $12 per person. Now what they had no eggs, old fruit (melon mostly) hard crusty oatmeal, and 2 cereals with no ..."

Reviewed on Oct 6, 2026

Hilton Garden Inn San Diego Mission Valley Stadium
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is CA $216 per night from Oct 25 to Oct 26
CA $216
CA $300 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
Wyndham San Diego Bayside
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is CA $296 per night from Nov 1 to Nov 2
CA $296
CA $415 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Paradise Point Resort & Spa
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is CA $159 per night from Nov 1 to Nov 2
CA $159
CA $182 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
Handlery Hotel
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
The price is CA $198 per night from Oct 25 to Oct 26
CA $198
CA $299 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Sheraton San Diego Resort
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
The price is CA $225 per night from Nov 2 to Nov 3
CA $225
CA $258 total
Nov 2 - Nov 3
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,997 reviews)
"Great location and friendly staff."

Reviewed on Oct 7, 2026

Bay Club Hotel & Marina
See all 9,588 properties in Kearny Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Kearny Mesa

Find the best Kearny Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Kearny Mesa
Learn more about Kearny Mesa
A large stadium with the sign "Cobo Park" and palm trees around it.

Downtown San Diego

Petco Park and Port of San Diego are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.
A pier extending into the ocean with buildings at the end, under a partly cloudy sky.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
A coastal cityscape with a long sandy beach, a pier, and dense urban buildings.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Nova SD is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.
An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.

Kearny Mesa

Choose two or more items and save on your trip:

Explore a world of travel with Expedia