Title: Book the Best Salem SPA Resorts from CA $516 - Spa Hotels in Salem, SC | Expedia.ca

  

[Hotels in Salem](https://expedia.ca/Salem-Hotels.d63870.Travel-Guide-Hotels)[Vacation Rentals in Salem](https://expedia.ca/Salem-Vacation-Rentals.d63870.Travel-Guide-VacationRentals)[Salem Car Rentals](https://expedia.ca/Car-Rentals-In-Salem.d63870.Car-Rental-Guide)[Salem Vacation Packages](https://expedia.ca/Salem.d63870.Destination-Travel-Guides)

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# Find Spa Hotels in Salem, SC from CA $516

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## Check availability on Salem Spa Hotels

Tonight

[Oct 22 - Oct 23](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-10-22&endDate=2025-10-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 23 - Oct 24](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-10-23&endDate=2025-10-24&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top Salem Spa Hotels

![Couples treatment rooms, body treatments, aromatherapy](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/70dd5eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/18582505.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dock](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/07befbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Library](https://images.trvl-media.com/lodging/24000000/23210000/23208600/23208596/ceeaab49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Greystone Inn

Lake Toxaway

9.4/10

Exceptional

(85)

"Gorgeous property with welcoming staff; excellent restaurant on property. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bailey

CA $419

CA $516 total

includes taxes & fees

Nov 9 - Nov 10

[](https://www.expedia.ca/Highlands-Hotels-Greystone-Inn.h23208596.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-05&endDate=2025-11-06&regionId=63870&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Salem Hotel Reviews

![Hampton Inn & Suites Cashiers Sapphire Valley](//images.trvl-media.com/lodging/2000000/1450000/1445800/1445731/f6504a0d_y.jpg)

### Hampton Inn & Suites Cashiers Sapphire Valley

10/10 Excellent

"Clean and spacious rooms with nice views. Close to restaurants and grocery store. Pleasant staff."

[](https://expedia.ca/Highlands-Hotels-Hampton-Inn-Suites-Cashiers-Sapphire-Valley.h1445731.Hotel-Information)

![Trailborn Highlands, Outdoor Collection by Marriott Bonvoy](//images.trvl-media.com/lodging/1000000/20000/13000/12956/cee1c17d_y.jpg)

### Trailborn Highlands, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Beautiful surroundings and convenient location. Great amenities."

[](https://expedia.ca/Highlands-Hotels-Trailborn-Highlands.h12956.Hotel-Information)

![Hampton Inn & Suites Seneca-Clemson Area](//images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/1436aba9_y.jpg)

### Hampton Inn & Suites Seneca-Clemson Area

10/10 Excellent

"All good. "

[](https://expedia.ca/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information)

## Frequently asked questions

### Looking to vacation at a spa hotel in Salem?

> Treat yourself to some pampering and book a hotel with a spa. Immerse yourself in nature at the lakeside setting and waterfalls in Salem. Be sure to enjoy activities like wakeboarding and golfing during your stay. Spa hotels are the perfect way to take a break from your routine and add a layer of luxury to your vacation.

### What's there to see and do in Salem?

> Take in the sights and attractions that Salem offers with a visit to Devils Fork State Park, Keowee Key Golf Course, and Lake Keowee. If you have a bit of extra time while you're in the area, you might want to check out Lake Jocassee and Nantahala National Forest.

### What is a Salem spa hotel?

> Spa hotels in Salem feature on-site spas and offer services such as massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.

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