Title: Book the Best Salem Hotels with Early Check-in in 2026 from CA $135 | Expedia.ca [Hotels in Salem](https://expedia.ca/Salem-Hotels.d63870.Travel-Guide-Hotels)[Vacation Rentals in Salem](https://expedia.ca/Salem-Vacation-Rentals.d63870.Travel-Guide-VacationRentals)[Salem Car Rentals](https://expedia.ca/Car-Rentals-In-Salem.d63870.Car-Rental-Guide)[Salem Vacation Packages](https://expedia.ca/Salem.d63870.Destination-Travel-Guides) ![Couple kayaking in remote lake](https://images.trvl-media.com/place/63870/969aae59-3d24-4cff-9457-a4cda46929a4.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels with Early Check-in in Salem, SC from CA $135 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Salem Hotels with Early Check-in Tonight [Dec 15 - Dec 16](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 16 - Dec 17](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=63870&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Salem hotels with express check-in ![Balcony](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/9fe06894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/a9307e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Seneca Clemson Univ Area [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) Seneca 9.4/10 Exceptional (204) "Nice hotel by the lake" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $158 CA $174 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/56d69457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/cbe6a617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (557) "location is amazing! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) colleen [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/a42189bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Single Room](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/8c83b96e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (78) "The owners are amazing. Comfy rooms, stellar breakfast and good people. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee CA $171 CA $259 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-050d425f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Clemson Hotel & Conference Center [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) Clemson 8.2/10 Very good (1004) " Clean room, breakfast, staff very nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Claudia CA $122 CA $135 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/13000000/12660000/12651500/12651466/ebc6c4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/13000000/12660000/12651500/12651466/55dc713c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Outland Skyhaus | Private kitchen](https://images.trvl-media.com/lodging/13000000/12660000/12651500/12651466/f15455d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/13000000/12660000/12651500/12651466/b4caf0a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cashiers [](https://www.expedia.ca/Cashiers-Hotels-Hotel-Cashiers.h12651466.Hotel-Information) Cashiers 8.8/10 Excellent (310) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adan CA $181 CA $205 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Cashiers-Hotels-Hotel-Cashiers.h12651466.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/12000000/11890000/11881100/11881029/0de126cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11890000/11881100/11881029/c1d03358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Terrace](https://images.trvl-media.com/lodging/12000000/11890000/11881100/11881029/aa62c356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Standard](https://images.trvl-media.com/lodging/12000000/11890000/11881100/11881029/33778224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Outpost Inn [](https://www.expedia.ca/Highlands-Hotels-The-Wells-Hotel.h11881029.Hotel-Information) Highlands 8.6/10 Excellent (294) "Very clean room, excellent staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pamela CA $249 CA $295 total includes taxes & fees Jan 5 - Jan 6, 2026 [](https://www.expedia.ca/Highlands-Hotels-The-Wells-Hotel.h11881029.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/b7a1f289.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/de9f5026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/7411cba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball, books](https://images.trvl-media.com/lodging/90000000/89410000/89406600/89406578/d57b249b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Welcome To Downtown Pickens close to Clemson and Lake Keowee [](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) Pickens 9.8/10 Exceptional (30) "We enjoyed our stay at this lovely home! Checking was easy and kitchen was roomy and met our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carla B. CA $149 CA $362 total includes taxes & fees Dec 29 - Dec 30 [](https://www.expedia.ca/Pickens-Hotels-Welcome-To-Downtown-Pickens-Close-To-Clemson-And-Lake-Keowee.h89406578.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-30&endDate=2025-12-31®ionId=63870&adults=2&property_amenities_group_explore=express_checkin&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Salem ### Discover top Salem attractions Salem, South Carolina, is a hidden gem perfect for looking for an enriching travel experience. Begin your adventure at Lake Hartwell, where families can enjoy boating, fishing, and hiking along scenic trails. The lake's pristine waters and picturesque views make it an ideal spot for a relaxing day outdoors. Next, explore the charming downtown area, where you can visit local boutiques and enjoy a meal at one of the family-friendly restaurants serving delicious Southern cuisine. For history enthusiasts, the nearby Oconee Heritage Center offers insights into the region's rich cultural tapestry, hosting fascinating exhibits and events. Additionally, nature lovers can embark on a hiking expedition in the nearby Sumter National Forest, known for its stunning landscapes and diverse wildlife. After a day of exploring, consider staying at one of the hotels near the lake, where you can unwind with views of the water and enjoy top amenities, ensuring that your family is pampered after an exciting day. 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