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Your Port Isabel Vacation

When a break in the city is calling, answer it with a Port Isabel vacation package. The neighborhood of The Shores, which is great for families, watersports and nature, makes an excellent base for your adventures. Every trip to Port Isabel needs a well-thought-out itinerary. Fill yours with big-name attractions like Beach Park at Isla Blanca, South Padre Island Beach and Boca Chica State Park. Stop daydreaming and start adventuring. Explore the wide range of options on Expedia today and put your Port Isabel vacation plans into action!

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Port Isabel Hotel Deals

Spacious Bay

35 Spacious way Port Isabel TX

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Port Isla Inn

200 2nd St Port Isabel TX

Fully refundableReserve now, pay when you stay

CA $94

CA $109 total

Jul 20 - Jul 21

includes taxes & fees

8/10 Very good! (965 reviews)

"We enjoyed the size of the suite but the bath tub would not hold water. The drain was broken. The place did come with 2 TV's but only 1 worked. The pool was nicely kept and there were picnic tables out and grills as well to use. The area was quiet and had easy access. Only complaint was the rooms ..."

Reviewed on Jun 26, 2026

Casa Rosa Inn

761 W. Highway 100 Port Isabel TX

Fully refundable

CA $83

CA $111 total

Jul 12 - Jul 13

includes taxes & fees

7.8/10 Good! (553 reviews)

"Clean room, but people stay in the pool until 3am and it was very loud!!!"

Reviewed on Jun 22, 2026

See all 3,828 properties in Port Isabel

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.