Title: Book the Best Pendleton SPA Resorts from CA $458 - Spa Hotels in Pendleton, SC | Expedia.ca [Hotels in Pendleton](https://expedia.ca/Pendleton-Hotels.d144669.Travel-Guide-Hotels)[Vacation Rentals in Pendleton](https://expedia.ca/Pendleton-Vacation-Rentals.d144669.Travel-Guide-VacationRentals)[Pendleton Car Rentals](https://expedia.ca/Car-Rentals-In-Pendleton.d144669.Car-Rental-Guide)[Pendleton Vacation Packages](https://expedia.ca/Pendleton.d144669.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/8008185e365be300833fc868932f54fc.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by RVLuckyorWhat # Find Spa Hotels in Pendleton, SC from CA $458 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Pendleton Spa Hotels Tonight [Oct 14 - Oct 15](https://www.expedia.ca/Hotel-Search?regionId=144669&startDate=2025-10-14&endDate=2025-10-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 15 - Oct 16](https://www.expedia.ca/Hotel-Search?regionId=144669&startDate=2025-10-15&endDate=2025-10-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=144669&startDate=2025-10-17&endDate=2025-10-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=144669&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Pendleton Spa Hotels ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-72054b06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/0671c5e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/924dd6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection Greenville Downtown 9.6/10 Exceptional (392) "Very expensive but great location. " CA $406 CA $458 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-28&endDate=2025-10-29®ionId=144669&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Pendleton Hotel Reviews ![Hilton Greenville](//images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "The staff were very friendly. I checked out and left my phone in the room and they allowed me to go back in the room, no hassle at all to retrieve my phone!!" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Greenville Haywood](//images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "Clean rooms" [](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](//images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Everything is super nice and clean" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ## Frequently asked questions ### Looking to vacation at a spa hotel in Pendleton? > Forget the stress of everyday life and book yourself a lush spa hotel. Check out the churches and museums in Pendleton—your cultural tour starts here. Take part in recreational activities such as horseback riding during your vacation. Spa hotels are a great way to take a break from your routine and add a layer of luxury to your holiday. ### What's there to see and do in Pendleton? > When you're in Pendleton, enjoy exploring the sights and attractions here including T. Ed Garrison Arena, Lake Hartwell, and Pendleton District Commission. If you have a little extra time during your trip, you might want to make a stop at Woodburn and Twin Lakes Recreation Area. ### What is a Pendleton spa hotel? > Spa hotels in Pendleton feature full on-site spas and offer services such as therapies and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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