Santa Clara
Panama City
Visit Santa Clara
Things to do
Panama Canal: The Most Complete Wildlife Experience
CA $51
per adult
100% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
CA $140
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
CA $94
per adult
96% of travellers recommend
Panama City: Embera Native Village & Waterfall Tour & Lunch
CA $92
per adult
From Panama City: San Blas Islands Tour with Island Hopping
CA $205
per adult
98% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
CA $45
per adult
100% of travellers recommend
Santa Clara Hotel Deals
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is CA $185 per night from Dec 3 to Dec 4
CA $185
CA $203 total
Dec 3 - Dec 4
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (6,186 reviews)
"The room was very clean, the staff at Riu Plaza was very pleasant and courteous despite the language barrier."
Reviewed on Nov 7, 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
The price is CA $151 per night from Dec 6 to Dec 7
CA $151
CA $166 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (1,012 reviews)
"Desayuno delicioso"
Reviewed on Nov 6, 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is CA $191 per night from Dec 7 to Dec 8
CA $191
CA $219 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
The price is CA $368 per night from Dec 8 to Dec 9
CA $368
CA $368 total
Dec 8 - Dec 9
includes taxes & fees
Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall ...
7.8/10 Good! (1,124 reviews)
"The property is really amazing staff was friendly and helpful only issue was the elevator was out of order often."
Reviewed on Nov 6, 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
The price is CA $134 per night from Nov 17 to Nov 18
CA $134
CA $147 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this business-friendly hotel in Panama City. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,422 reviews)
"The breakfast is very good beside a regular sausage and egg, also you can prepare your own boiled egg very good dessert"
Reviewed on Nov 7, 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is CA $187 per night from Nov 15 to Nov 16
CA $187
CA $205 total
Nov 15 - Nov 16
includes taxes & fees
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (1,845 reviews)
"The saying "you get what you pay for", applies to this hotel. The room that I initially checked in, the bathroom vent was buzzing. I called to have it fixed. I used the bathroom as I waited. When I flushed the toilet; it overflowed. I changed rooms the next day. Had the same issue with the vent. ..."
Reviewed on Nov 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Clara
Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.
El Cangrejo
The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.
