Santa Clara Vacation Packages

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Your Santa Clara Vacation

Lock in a Santa Clara vacation package that has everything you need without any unnecessary extras. Great for distilleries and craft breweries, bars and pubs and cafes, think about staying in the neighborhood of El Cangrejo. A trip to Santa Clara is an excellent opportunity to take in the sights. Make sure you visit big-name attractions such as Multiplaza Pacific Mall, Avenida Balboa and Via Espana. A few clicks is all it takes to create a customized Santa Clara vacation on Expedia.

Top Holiday Package Deals in Santa Clara

Price found within the past 48 hours. Click for updated prices.
Summit Rainforest & Golf Resort

Summit Rainforest & Golf Resort

4 out of 5
Price was CA $1,563, price is now CA $1,142 per person
CA $1,142
per person
May 10 - May 17
found 7 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
8.4/10 Very Good! (1,002 reviews)
Everyone was welcoming. We wished to have supper under the stars and that was accomplished. It was almost closing time when we arrived. I was served a massive tasty hamburger. Biggest I've ever seen. Breakfast was a bit disappointing. The coffee was delicious.

Reviewed on Mar 3, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was CA $3,179, price is now CA $1,871 per person
CA $1,871
per person
May 10 - May 17
found 7 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (1,008 reviews)
The staff was great an the hotel

Reviewed on Mar 2, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was CA $2,436, price is now CA $1,599 per person
CA $1,599
per person
May 10 - May 17
found 7 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
8.4/10 Very Good! (1,437 reviews)
View of the city but you can ask prior arrival your prefernce. Shops are nearby

Reviewed on Mar 2, 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was CA $1,911, price is now CA $1,296 per person
CA $1,296
per person
May 10 - May 17
found 7 hours ago
Roundtrip non-stop flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (5,027 reviews)
Close by a lot of eating options

Reviewed on Mar 5, 2026

Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was CA $2,042, price is now CA $1,420 per person
CA $1,420
per person
Apr 25 - May 2
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
9/10 Wonderful! (143 reviews)
J’ai tout aimé de l’endroit qui était féerique, tranquille, directement sur le bord de la plage. Le personnel impeccable et la chambre parfaite et confortable 😊

Reviewed on Feb 23, 2026

Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most. Learn more about Santa Clara
View of the Panama City Old Town

Casco Viejo

4/5(32 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Santa Clara Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is CA $201 per night from Mar 30 to Mar 31
CA $201
CA $221 total
Mar 30 - Mar 31
includes taxes & fees
9/10 Wonderful! (5,077 reviews)
Close by a lot of eating options

Reviewed on Mar 5, 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
8.6/10 Excellent! (2,473 reviews)
Shuttle was easy to find. Good service everywhere l. Comfortable beds

Reviewed on Mar 5, 2026

Get rates
Crowne Plaza Panama Airport by IHG
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Mar 23 to Mar 24
CA $147
CA $162 total
Mar 23 - Mar 24
includes taxes & fees
7.8/10 Good! (1,012 reviews)
Was clean but very noisy pool area on weekends

Reviewed on Mar 3, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
See all 1,575 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
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Frequently asked questions

How much does a Santa Clara vacation package cost?
Custom make your Santa Clara vacation package from as little as CA $1,142. Pick from any combination of hotels, flights and rental cars to craft the escape of your dreams. Be sure to add on some tours and experiences!
How do I get a cheap travel package to Santa Clara?
One of the easiest ways to save cash (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got them all. Select the combination that best fits you and watch your savings grow. Of course, a travel package is never a one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Clara getaway.
Where should I stay in Santa Clara?
Most travelers who visit Santa Clara include Miraflores Locks and Metropolitan Cathedral of Panama on their must-see lists. Why not select a hotel close to one of these main attractions?
How far in advance should I book my Santa Clara vacation?
Savvy travelers always book early. Air carriers generally advertise flights up to a year prior to departure, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you should take some vacation time next week? No need to worry. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Santa Clara travel package include?
It comes down to what you're looking for. If you're traveling solo, you might decide to combine hotels and flights. Bringing the whole family to Santa Clara? A travel package including flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking a Santa Clara travel package?
When you book your flights, hotels and car rentals together, you'll pick up awesome discounts. Whether you're organizing a beach break in a villa or prefer to stay in an upscale city hotel, Expedia can make it happen for less.
Can I choose my airline with a Santa Clara Expedia vacation package?
Yes, you can. We offer more than 550 airline partners throughout the world, so opt for the carrier that fits your budget and travel needs.
If I'm not able to travel, can I cancel my Santa Clara vacation package?
Because we understand life is full of surprises, the answer is yes. For further details, check out our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.

Discover the most popular places to visit in Santa Clara

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Panama City night skyline

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Old and traditional Yatch Club at Cinta Costera, Panama City, Panama.

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera

Things to do

Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

CA $44
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Tour to a waterfall and Embera village with lunch included

Tour to a waterfall and Embera village with lunch included

CA $69
per adult
100% of travellers recommend
Tour to a waterfall and Embera village with lunch included
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City

CA $136
per adult
96% of travellers recommend
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.