Santa Clara Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santa Clara Vacation Packages
- Riande Aeropuerto Hotel & Casino
Oct 15 - Oct 20Riande Aeropuerto Hotel & Casino + Flight
Tocumen4 nights4.0 star property8.4/10 - Very good (1,819 reviews)"there was only one bar and no entertainment at all one restaurant well"Reviewed August 6, 2026Roundtrip • Montreal (YUL) - Panama City (PTY)YUL - PTY • 1 stop PTY - YUL • 1 stopCA $1,623CA $1,189found 1 day agoper traveller - Central Hotel Panama Casco Viejo
Oct 10 - Oct 14Central Hotel Panama Casco Viejo + Flight
Casco Viejo4 nights4.0 star property9.2/10 - Wonderful (1,013 reviews)"The hotel is as the name indicated, in the center of old town. The location is fantastic. Very convenient. However, as some of the reviews had mentioned, they have live music in the lobby all day until 11pm. I was aware of this and requested that they give us a quiet room. However, we were given a room with windows facing the atrium and were subjected to the music all day. It was not too loud but was quite annoying if you want quietness. Add to this, it was on the 4th floor and next to one..."Reviewed August 6, 2026Roundtrip • Toronto (YTO) - Panama City (PTY)YYZ - PTY • 1 stop PTY - YYZ • 1 stopCA $2,339CA $1,408found 1 day agoper traveller - Megapolis Hotel Panamá
Sept 30 - Oct 4Megapolis Hotel Panamá + Flight
San Francisco4 nights4.5 star property8.4/10 - Very good (1,636 reviews)Roundtrip • Toronto (YTO) - Panama City (PTY)YYZ - PTY • 1 stop PTY - YYZ • 1 stopCA $2,393CA $1,459found 1 day agoper traveller - Brisas del Mar by Playa Caracol Resorts
Oct 17 - Oct 23Brisas del Mar by Playa Caracol Resorts + Flight
Punta Chame6 nights4.5 star property2.0/10 - (1 review)"Arrived at ny 12 noon check in per my registration with a couple of bags of perishable items to cook over the stay. Once I arrived I was told that they do not do check in until 3 PM. I showed them that the check in per my reservation was at 12 noon and that I had purchased food that could not sit in a hot car for three hours. I was told that they would expedite the room cleaning and inform me soon on the check in. I returned in 45 minuted and there was another associate there that stated that..."Reviewed January 12, 2026Roundtrip • Toronto (YYZ) - Panama City (PTY)YYZ - PTY • Nonstop PTY - YYZ • NonstopCA $1,715CA $1,324found 5 hours agoper traveller - Boutique Apartments Panamá Coco del Mar
Oct 26 - Nov 1Boutique Apartments Panamá Coco del Mar + Flight
San Francisco5 nights3.5 star property7.6/10 - Good (211 reviews)"Great location"Reviewed August 2, 2026Roundtrip • Montreal (YMQ) - Panama City (PTY)YUL - PTY • 1 stop PTY - YUL • 1 stopCA $1,727CA $1,345found 1 day agoper traveller
Frequently Asked Questions
How much does a Santa Clara vacation package cost?
Custom make your Santa Clara vacation package from as little as CA $1,189. Pick from any combination of hotels, flights and rental cars to craft the escape of your dreams. Be sure to add on some tours and experiences!
How do I get a cheap travel package to Santa Clara?
One of the easiest ways to save cash (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got them all. Select the combination that best fits you and watch your savings grow. Of course, a travel package is never a one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Clara getaway.
Where should I stay in Santa Clara?
Most travelers who visit Santa Clara include Miraflores Locks and Metropolitan Cathedral of Panama on their must-see lists. Why not select a hotel close to one of these main attractions?
How far in advance should I book my Santa Clara vacation?
Savvy travelers always book early. Air carriers generally advertise flights up to a year prior to departure, and this is a fantastic opportunity to score some of the cheapest prices. Just been told you should take some vacation time next week? No need to worry. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.
What does an Expedia Santa Clara travel package include?
It comes down to what you're looking for. If you're traveling solo, you might decide to combine hotels and flights. Bringing the whole family to Santa Clara? A travel package including flights, hotels and rental cars might suit you better. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking a Santa Clara travel package?
When you book your flights, hotels and car rentals together, you'll pick up awesome discounts. Whether you're organizing a beach break in a villa or prefer to stay in an upscale city hotel, Expedia can make it happen for less.
Can I choose my airline with a Santa Clara Expedia vacation package?
Yes, you can. We offer more than 550 airline partners throughout the world, so opt for the carrier that fits your budget and travel needs.
If I'm not able to travel, can I cancel my Santa Clara vacation package?
Because we understand life is full of surprises, the answer is yes. For further details, check out our Customer Service Portal. But generally speaking, if you've made your booking in the last 24 hours, you may be able to change or cancel it for no charge. Your hotel, airline or car rental company may impose a fee if you made your booking a while ago.