O'Fallon Vacation Rentals

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Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for O'Fallon vacation rentals

A dining area with a table and chairs, a ceiling fan, and a wall-mounted flower painting.

1. The Cozy Family Retreat

The Cozy Family Retreat
O'Fallon
7.8 out of 10, Good, (27 reviews)
"Location was great, potential was unabated. Execution was absolutely terrible. "
United States
clint a.
The price is CA $160
CA $420 total
includes taxes & fees
Nov 8 - Nov 9
The Cozy Family Retreat
A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

2. 1 Bedroom | Pool & Gym. Free Breakfast

1 Bedroom | Pool & Gym. Free Breakfast
O'Fallon
8.4 out of 10, Very good, (5 reviews)
"It’s a suite hotel - rooms were very spacious. It’s in a great location. Staff is welcoming and kind. It was exactly what we needed for a last minute trip to check on family."
United States
Melinda C.
The price is CA $220
CA $271 total
includes taxes & fees
Nov 8 - Nov 9
1 Bedroom | Pool & Gym. Free Breakfast
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.

3. Centrally located, spacious 4 bdrm, on quiet Ct

Centrally located, spacious 4 bdrm, on quiet Ct
O'Fallon
10.0 out of 10, Exceptional, (26 reviews)
"Great host and beautiful of house"
United States
William M.
The price is CA $209
CA $604 total
includes taxes & fees
Nov 12 - Nov 13
Centrally located, spacious 4 bdrm, on quiet Ct
A hotel room with a large bed, a nightstand with a lamp, a painting on the wall, and a window with curtains.

4. Pet-Friendly 2BR Townhome with Workspace

Pet-Friendly 2BR Townhome with Workspace
O Fallon
9.8 out of 10, Exceptional, (17 reviews)
"I have stayed here before and enjoy the comfortable mattress and backyard and full kitchen. It works well for me and is close to O’Fallon city center which is what I needed."
United States
Tricia S.
The price is CA $204
CA $535 total
includes taxes & fees
Nov 8 - Nov 9
Pet-Friendly 2BR Townhome with Workspace
A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

5. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
7.0 out of 10, Good, (2 reviews)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
The price is CA $220
CA $271 total
includes taxes & fees
Nov 8 - Nov 9
Great for Business Travelers! Pool + Gym
A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

6. Accessible 2BR Suite w/ Pool & Free Hot Breakfast

Accessible 2BR Suite w/ Pool & Free Hot Breakfast
O'Fallon
The price is CA $327
CA $403 total
includes taxes & fees
Nov 8 - Nov 9
Accessible 2BR Suite w/ Pool & Free Hot Breakfast
A living room with a glass coffee table, two beige sofas, a wooden cabinet, and a ceiling fan.

7. Spacious 5-bedroom house in serene O'Fallon with AC

Spacious 5-bedroom house in serene O'Fallon with AC
O'Fallon
9.8 out of 10, Exceptional, (12 reviews)
"Nice place "
United States
RAMONA O E.
The price is CA $419
CA $814 total
includes taxes & fees
Nov 9 - Nov 10
Spacious 5-bedroom house in serene O'Fallon with AC
A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

8. Free Breakfast. Pool & Gym. Near Progress West Hospital!

Free Breakfast. Pool & Gym. Near Progress West Hospital!
O'Fallon
9.0 out of 10, Wonderful, (2 reviews)
The price is CA $245
CA $300 total
includes taxes & fees
Nov 8 - Nov 9
Free Breakfast. Pool & Gym. Near Progress West Hospital!
A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

9. King Suite. Free Breakfast. Pool & Gym. Your Next Trip!

King Suite. Free Breakfast. Pool & Gym. Your Next Trip!
O'Fallon
10.0 out of 10, Exceptional, (1 review)
"We needed a place to stay near to events in Lake St. Louis. This was perfect for us. Quiet. Easy access. Nice to have a small kitchenette area, shower/tub, and big fridge. "
United States
Shawna P.
The price is CA $245
CA $300 total
includes taxes & fees
Nov 8 - Nov 9
King Suite. Free Breakfast. Pool & Gym. Your Next Trip!
A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

10. Pool & Gym. Your Next Trip!

Pool & Gym. Your Next Trip!
O'Fallon
8.0 out of 10, Very good, (3 reviews)
"It was a fine short stay. Good breakfast!!"
United States
Elizabeth B.
The price is CA $327
CA $404 total
includes taxes & fees
Nov 8 - Nov 9
Pool & Gym. Your Next Trip!
A residential building with a patio area featuring outdoor furniture and string lights.

11. Private Entry Basement Suite • Pond & Farm View • Dog Friendly • St Peters

Private Entry Basement Suite • Pond & Farm View • Dog Friendly • St Peters
St. Peters
10.0 out of 10, Exceptional, (21 reviews)
"What a great place to stay! Clean, well stocked, and very spacious. Would definitely book again."
United States
Lynn D.
The price is CA $133
CA $391 total
includes taxes & fees
Dec 6 - Dec 7
Private Entry Basement Suite • Pond & Farm View • Dog Friendly • St Peters
A spacious kitchen with white cabinets, a central island with bar stools, a stainless steel refrigerator, and a microwave.

12. Spacious, 3 bedroom home, finished basement on quiet court

Spacious, 3 bedroom home, finished basement on quiet court
St. Peters
9.8 out of 10, Exceptional, (58 reviews)
"Great place"
United States
ed n.
The price is CA $189
CA $582 total
includes taxes & fees
Nov 8 - Nov 9
Spacious, 3 bedroom home, finished basement on quiet court
A spacious living area with a dining table, chairs, a sofa, and a fireplace. There is a kitchen area with a refrigerator, stove, and cabinets. The room has large windows and a ceiling fan.

13. Lovely Couples Escape on Mississippi River!

Lovely Couples Escape on Mississippi River!
3.0 star property
St. Charles
10.0 out of 10, Exceptional, (4 reviews)
"The property was clean, easy to access, the property owner was easy to talk to and amazing. Loved staying there and will be staying again next year for the same bike race."
United States
Marina
Lovely Couples Escape on Mississippi River!
A room with a dark wooden wall, a brown leather sofa, a white door, and a patterned wall.

14. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (4 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is CA $175
CA $424 total
includes taxes & fees
Nov 7 - Nov 8
Stylish1BRStudioCleanQuietandCozy
An outdoor hot tub area with seating and a covered patio.

15. Private Basement - Two King Beds and Hot Tub

Private Basement - Two King Beds and Hot Tub
Saint Charles
9.6 out of 10, Exceptional, (5 reviews)
"Clean. The patio was very comfortable and nice to sit and relax. The beds were also very comfortable."
United States
Beth S.
The price is CA $119
CA $442 total
includes taxes & fees
Nov 15 - Nov 16
Private Basement - Two King Beds and Hot Tub
A kitchen with a stainless steel sink, a gold faucet, and a bottle of hand soap.

16. Wentzville King Bed Walk to Downtown!

Wentzville King Bed Walk to Downtown!
Wentzville
9.0 out of 10, Wonderful, (2 reviews)
"Most everything was good. I do recommend correcting the upward slope on the top of the step from the living area to the bedroom area. As you approach from the kitchen, the slight rise in the floor throws off your balance going down the step. Wrenched my back and legs when awkwardly hitting the lower level."
United States
Alan G.
The price is CA $150
CA $497 total
includes taxes & fees
Nov 9 - Nov 10
Wentzville King Bed Walk to Downtown!
A bedroom with two beds, a ceiling fan, and a window with blue curtains.

17. 4BR Marvel House Game Room, Sleeps 14

4BR Marvel House Game Room, Sleeps 14
St. Peters
9.2 out of 10, Wonderful, (5 reviews)
"Decorated nicely and everything was new. Very clean and beds were so comfortable. Lots of extras included by host. Pet friendly and fenced in yard was wonderful for dogs"
United States
Ann S.
The price is CA $313
CA $690 total
includes taxes & fees
Nov 10 - Nov 11
4BR Marvel House Game Room, Sleeps 14
A rustic bar area with stone walls, wooden chairs, and hanging pendant lights.

18. Bright Lakefront Studio Condo at Innsbrook

Bright Lakefront Studio Condo at Innsbrook
Wright City
9.8 out of 10, Exceptional, (74 reviews)
"everything was clean and really beautiful, we enjoyed the stay "
United States
Vanessa O.
The price is CA $101
CA $254 total
includes taxes & fees
Nov 8 - Nov 9
Bright Lakefront Studio Condo at Innsbrook
Clubhouse

19. Serene Seebach Sights by Innsbrook Vacations!

Serene Seebach Sights by Innsbrook Vacations!
Innsbrook
9.6 out of 10, Exceptional, (15 reviews)
"Great clubhouse, plenty of wildlife roaming grounds, and friendly atmosphere."
United States
tony
Serene Seebach Sights by Innsbrook Vacations!
A modern kitchen with a stainless steel refrigerator, an island with pink stools, a gas stove, and a large window.

20. Completely Renovated Home in St. Charles, Missouri

Completely Renovated Home in St. Charles, Missouri
Saint Charles
10.0 out of 10, Exceptional, (1 review)
"Close proximity to our job site. Quiet neighborhood."
United States
Herbert L.
The price is CA $192
CA $598 total
includes taxes & fees
Nov 18 - Nov 19
Completely Renovated Home in St. Charles, Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O'Fallon Hotel Reviews

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.
Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
St. Peters

10/10 Excellent

If possible I will always stay at a Drury Hotel. The buffet breakfast was actually good and I didn't even know that dinner is included. And it was actually good too. The hotel was wonderful and the staff were very friendly and helpful too.
Canada
Daryl
Reviewed April 10, 2026
Drury Inn & Suites St. Louis St. Peters

Find out more about O'Fallon

Everything you need to know about O'Fallon vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the O'Fallon vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect O'Fallon vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

O'Fallon vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in O'Fallon. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A O'Fallon vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of O'Fallon vacation rentals we have selected for you start as low as CA $100 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on O'Fallon rentals

At Expedia, we put the best O'Fallon vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top O'Fallon rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream O'Fallon vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around O'Fallon. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Are there vacation rentals in O'Fallon?

Yes, we have vacation rentals in O'Fallon near Alligator Creek Aquatic Center, or you can choose a more secluded option if you'd like a relaxing place to stay. The shops and restaurants are several reasons why visitors like O'Fallon. Make sure you have time to check out the baseball games and cafes during your trip.

What's the top vacation rental in O'Fallon?

HotTub-2br2b-near Historic Main Street: Visitors like this O'Fallon vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Make the most of the hot tub in this rental home to help you unwind.

How many vacation rentals will I find in O'Fallon?

With 13 Expedia vacation rentals, you're sure to find just the right place for your O'Fallon stay.

What can I see and do in O'Fallon?

Family-friendly attractions include Alligator Creek Aquatic Center, whereas Mississippi River is a spot to enjoy the outdoors. While here, CarShield Field and 9-11 Memorial are other places worth a visit.

What are vacation rentals like in O'Fallon?

Vacation rentals are private accommodations you can reserve for a couple days or more in O'Fallon. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular choice for family gatherings.