Default HTG hotel image

Hotels in O'Fallon, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for O'Fallon hotels

A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

1. The West End

The West End
2.0 star property
Central West End, 4.1 km from O'Fallon
8.6 out of 10, Excellent, (662 reviews)
"Very clean room and really good customer service"
United States
Sergio
The price is CA $118
CA $166 total
includes taxes & fees
Oct 4 - Oct 5
The West End
An indoor swimming pool with a hot tub, lounge chairs, and a brick wall with artwork.

2. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 4.9 km from O'Fallon
8.8 out of 10, Excellent, (2,217 reviews)
"The pool and food and rooms were nice"
United States
Michael
The price is CA $148
CA $173 total
includes taxes & fees
Oct 11 - Oct 12
Pear Tree Inn St. Louis Near Union Station
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

3. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 5.6 km from O'Fallon
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location"
United States
Kristy
The price is CA $138
CA $164 total
includes taxes & fees
Oct 31 - Nov 1
Courtyard by Marriott St. Louis Downtown/Convention Center
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

4. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
3.8 km from O'Fallon
8.8 out of 10, Excellent, (1,164 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is CA $168
CA $198 total
includes taxes & fees
Oct 7 - Oct 8
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A pool area with clear water, red lounge chairs, and a view of the outside through large windows.

5. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 4.8 km from O'Fallon
8.6 out of 10, Excellent, (1,002 reviews)
"Lovely location and amazing room"
United States
Jacob
The price is CA $162
CA $189 total
includes taxes & fees
Oct 11 - Oct 12
Aloft by Marriott St Louis Central West End
An indoor pool area with a hot tub, seating, and a stone wall.

6. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
3.0 star property
Downtown West, 5.2 km from O'Fallon
9.4 out of 10, Exceptional, (1,562 reviews)
"Enjoyable stay."
United States
Robert
The price is CA $167
CA $198 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Union Station
An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

7. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 4.6 km from O'Fallon
8.8 out of 10, Excellent, (1,002 reviews)
"Room was clean and staff were friendly!"
United States
Lydia
The price is CA $191
CA $241 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Indigo St Louis - Central West End by IHG
The Clayton Plaza Hotel sign with a stone wall and plants in front.

8. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
10 km from O'Fallon
8.8 out of 10, Excellent, (3,447 reviews)
"Great place to stay."
United States
Sivakumar
The price is CA $134
CA $156 total
includes taxes & fees
Oct 25 - Oct 26
Clayton Plaza Hotel & Extended Stay
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

9. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 6.8 km from O'Fallon
9.4 out of 10, Exceptional, (1,000 reviews)
"This was an excellent location and the front desk staff made great recommendations for places to eat and things to do."
United States
Jennifer
The price is CA $197
CA $232 total
includes taxes & fees
Oct 11 - Oct 12
Hampton Inn & Suites St. Louis at Forest Park
A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and a brick facade.

10. Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 6.5 km from O'Fallon
8.2 out of 10, Very good, (415 reviews)
"Loved the breakfast."
United States
Daevontae
The price is CA $147
CA $172 total
includes taxes & fees
Oct 29 - Oct 30
Comfort Inn & Suites Saint Louis Lafayette Square
A rooftop terrace with wicker furniture, offering a city view.

11. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 6.3 km from O'Fallon
9.6 out of 10, Exceptional, (3,761 reviews)
"Excellent stay"
United States
Salvatore
The price is CA $192
CA $225 total
includes taxes & fees
Oct 11 - Oct 12
Drury Plaza Hotel St. Louis at the Arch
A hotel room with two beds, a chair, a desk, and a large window.

12. Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 8.1 km from O'Fallon
7.4 out of 10, Good, (1,651 reviews)
"Comfortable bed and room. Friendly staff. Convenient location."
United States
Janice
The price is CA $110
CA $135 total
includes taxes & fees
Nov 1 - Nov 2
Forest Park Hotel by MDR
A rooftop restaurant with round tables, chairs, and a view of the city.

13. Moonrise Hotel

Moonrise Hotel
4.0 star property
6.6 km from O'Fallon
9.0 out of 10, Wonderful, (2,031 reviews)
"Great location"
United States
Katherine
The price is CA $188
CA $223 total
includes taxes & fees
Oct 4 - Oct 5
Moonrise Hotel
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

14. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 5.1 km from O'Fallon
9.0 out of 10, Wonderful, (2,120 reviews)
"Great place to stay!"
United States
Zane
The price is CA $204
CA $246 total
includes taxes & fees
Oct 25 - Oct 26
21C Museum Hotel St Louis
An indoor swimming pool with a glass ceiling, surrounded by potted plants and a tiled wall with a geometric pattern.

15. Casino Queen Hotel

Casino Queen Hotel
3.0 star property
6.9 km from O'Fallon
7.8 out of 10, Good, (2,165 reviews)
"Nice stay"
United States
Shawna
The price is CA $106
CA $122 total
includes taxes & fees
Oct 4 - Oct 5
Casino Queen Hotel
A lobby with a reception desk, seating area, and a bicycle in the background.

16. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
8.3 km from O'Fallon
9.4 out of 10, Exceptional, (1,019 reviews)
"Great place to stay"
United States
Robert
The price is CA $192
CA $225 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites St. Louis Forest Park
A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

17. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 5 km from O'Fallon
9.2 out of 10, Wonderful, (1,001 reviews)
"Nice hotel, great staff. Directly across the street from Energizer/City Park. Parking is $25/night and well worth it."
United States
James
The price is CA $165
CA $197 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott St. Louis Downtown
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

18. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 5.6 km from O'Fallon
8.6 out of 10, Excellent, (1,002 reviews)
"Staff was nice and helpful food was great and room was amazing!!! "
United States
paullita jeanne
The price is CA $222
CA $259 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton St. Louis/Forest Park
An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

19. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
3.5 star property
Downtown St. Louis, 6 km from O'Fallon
8.8 out of 10, Excellent, (1,426 reviews)
"Staff was very friendly and room was awesome."
United States
Andy
The price is CA $150
CA $176 total
includes taxes & fees
Oct 28 - Oct 29
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
A lobby with a sofa, two armchairs, a coffee table, and a staircase.

20. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 6.2 km from O'Fallon
8.6 out of 10, Excellent, (4,325 reviews)
"Great place to stay"
United States
David
The price is CA $204
CA $240 total
includes taxes & fees
Oct 30 - Oct 31
Hyatt Regency St. Louis at The Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in O'Fallon

Find the best O'Fallon areas and neighborhoods for the activities you enjoy most. Learn more about O'Fallon
Learn more about O'Fallon
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
A historic building with ornate architecture, outdoor seating, and a parked SUV.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Top O'Fallon Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Very friendly and helpful staff. Good breakfast and clean room."
Donnie 1-night trip
Posted 1 hour ago
Pear Tree Inn St. Louis Near Union Station

Frequently asked questions

What is O'Fallon like?
Travelers to St. Louis's O'Fallon neighborhood will be sure to enjoy a stay in this neighborhood.
If I need to cancel my hotel reservation in O'Fallon, will I receive a refund?
Yes, most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals in O'Fallon.
What is there to do in this St. Louis neighborhood?
Julia Davis Branch Library, Shelley House, and Sumner High School are just a few of the places to visit in and around O'Fallon. The Ville Monument and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.