Title: The 10 Best Hotels Near Museum of Life and Science, Raleigh from CA $92 | Expedia.ca [Raleigh Travel Guide](https://expedia.ca/Raleigh.dx178300)[Vacation Rentals in Raleigh](https://expedia.ca/Raleigh-Vacation-Rentals.d178300.Travel-Guide-VacationRentals)[Flights to Raleigh](https://expedia.ca/Cheap-Flights-To-Raleigh.d178300.Travel-Guide-Flights)[Things to do in Raleigh](https://expedia.ca/Things-To-Do-In-Raleigh.d178300.Travel-Guide-Activities)[Museum of Life and Science Car Rentals](https://expedia.ca/Car-Rentals-In-Museum-Of-Life-And-Science.d6066241.Car-Rental-Guide)[Museum of Life and Science Vacations](https://expedia.ca/Museum-Of-Life-And-Science-Raleigh.d6066241.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Museum of Life and Science, Raleigh from CA $92 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=6066241&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=6066241&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6066241&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6066241&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Museum of Life and Science ![Lobby](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/cecacec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/ae05b866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/a5c63916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/a3f8d81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Durham/North I-85 1.4 km from Museum of Life and Science 9.0/10 Wonderful (1012) "Nice place to stay and close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy CA $144 CA $164 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/b3df2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/567d1dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/0b17a097.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/28a254ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Durham by IHG 2.2 km from Museum of Life and Science 8.8/10 Excellent (944) "Love my stay , great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Oscar CA $144 CA $164 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/eefd1cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds (Smoke Free)](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/5451026c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed (Smoke Free) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/84d2f31a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/73d68be7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Durham - Duke Univ Medical Center 2.2 km from Museum of Life and Science 6.8/10 (1005) "Good motel...clean, easy acess " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Howard CA $79 CA $92 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/ae65d3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/c8136411.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/550fbdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Durham near Duke University Croasdaile Farm Master, 3.2 km from Museum of Life and Science 8.6/10 Excellent (1012) "Loved our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $126 CA $143 total includes taxes & fees Dec 28 - Dec 29 [](https://www.expedia.ca/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/1000000/860000/856400/856320/ec69b9bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/1000000/860000/856400/856320/fa02a73e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/860000/856400/856320/838962b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856400/856320/8e5b63e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Durham/University Area NC 2.1 km from Museum of Life and Science 5.0/10 (344) "The environment was not pleasant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $84 CA $95 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Raleigh-Hotels-Super-8-By-Wyndham-DurhamUniversity-Area-NC.h856320.Hotel-Information) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/86ba7427.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/1399f82d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/4c923195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/aa039182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to Duke Campus 3 Bedroom in Trinity Park Trinity Park, 2.9 km from Museum of Life and Science CA $109 CA $296 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Raleigh-Hotels-Walk-To-Duke-Campus-3-Bedroom-In-Trinity-Park.h113387562.Hotel-Information) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/f31da80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/19fc7ffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/b44f878a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/22fe0506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renovated 2 Bed Walltown Home Walk to Duke A 2.2 km from Museum of Life and Science CA $92 CA $251 total includes taxes & fees Dec 8 - Dec 9 [](https://www.expedia.ca/Raleigh-Hotels-Renovated-2-Bed-Walltown-Home-Walk-To-Duke-A.h113387569.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/0f42bc80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/c90f9818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds (Mobility Accessible, Tub)](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/94a88b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/8fa5480a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Durham McPherson/Duke University Medical Cntr Trinity Park, 3.3 km from Museum of Life and Science 9.2/10 Wonderful (458) "Hotel was great - very friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $161 CA $182 total includes taxes & fees Jan 2 - Jan 3, 2026 [](https://www.expedia.ca/Raleigh-Hotels-Residence-Inn-Durham-McPhersonDuke-University-Medical-Cntr.h10344567.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/2346fd7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/42803815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/41e379bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/3b234d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Durham/University Medical Center 9th Street District, 3.4 km from Museum of Life and Science 9.2/10 Wonderful (1007) "Clean rooms, nice staff. Clean hotel. Ample parking. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emana CA $171 CA $194 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/29cfc65c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/45c09dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/1219d801.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Durham Near Duke University/Downtown Croasdaile Farm Master, 3.3 km from Museum of Life and Science 8.2/10 Very good (1011) "Staff was wonderful, hotel clean, & location was perfect!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gena CA $147 CA $167 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24100/24026/38a21748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/24100/24026/4d70e818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24100/24026/8ae1adfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/30000/24100/24026/a8fd29ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Inn 4.4 km from Museum of Life and Science 5.8/10 (1030) "Awful “hotel”" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Andrew CA $112 CA $127 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Raleigh-Hotels-Royal-Inn.h24026.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10436/70510201.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/20000/10500/10436/4d604ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/10500/10436/2afd7380.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/10500/10436/1157ae47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Plus Hotel by Best Western Durham Medical Center 5.1 km from Museum of Life and Science 5.8/10 (1004) "Staff was nice & breakfast was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zelma CA $88 CA $99 total includes taxes & fees Dec 9 - Dec 10 [](https://www.expedia.ca/Raleigh-Hotels-Durham-Medical-Park-Inn-Suites.h10436.Hotel-Information) ![Daily cooked-to-order breakfast (USD 19.95 per person)](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/77870d0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/7fa8560d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/87483d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/64c7e604.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Durham Marriott City Center Downtown Durham, 3.6 km from Museum of Life and Science 8.8/10 Excellent (821) "The room was clean. The staff was very helpful and the food was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tia CA $177 CA $201 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Raleigh-Hotels-Durham-Marriott-City-Center.h23726.Hotel-Information) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/b7c32975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/3439b81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/f7b4838d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/55fc1f3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Durham Hotel Downtown Durham, 3.6 km from Museum of Life and Science 9.0/10 Wonderful (635) "Perfect place to stay for an easy walk to see a show at the charming Carolina Theater. Food, service and atmosphere were outstanding. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jo CA $260 CA $295 total includes taxes & fees Dec 7 - Dec 8 [](https://www.expedia.ca/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/0f9d6f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/ebe35e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/d6ccf805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/ce4d3dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Unscripted Durham, Part of JDV by Hyatt Downtown Durham, 3.7 km from Museum of Life and Science 8.2/10 Very good (1007) "Staff was nice, room was large and very clean, location was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice CA $178 CA $225 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/a66cf407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/eec8c639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/d1e30aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/52832fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Durham Downtown Durham, 3.7 km from Museum of Life and Science 8.4/10 Very good (1014) "Overall good hotel and friendly staff. Building and rooms show some age but that is part of the charm. Enjoyable stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa H CA $225 CA $263 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/81950088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/fa7de522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/641c37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/8ace6ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn Durham next to Duke University Medical Center 4 km from Museum of Life and Science 8.8/10 Excellent (1010) "Courteous staff, clean room" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bruce CA $150 CA $170 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/w4000h2662x0y0-c51072ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/505e32af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, City View](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/9f21eef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/73e55abf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Durham Downtown American Tobacco District, 4.1 km from Museum of Life and Science 9.0/10 Wonderful (730) "Very friendly staff, very clean and convenient location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $236 CA $268 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Raleigh-Hotels-Aloft-Durham-Downtown.h10088739.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/80000/79500/79455/fb1bc5ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/79500/79455/259705b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/80000/79500/79455/c125d817.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/79500/79455/7383be40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Suites Durham University 8.3 km from Museum of Life and Science 5.0/10 (818) "I would not recommend this place unless you are on a really tight budget. The only nice thing about it was the kind person who checked us in. The room was dingy and smelled faintly of smoke. The smoke alarm was chirping and I had to borrow tools to disconnect it so we could sleep. There was constant noise throughout the night from other guests, and the whole place smelled like weed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derek CA $102 CA $115 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/Raleigh-Hotels-Extended-Stay-America-Suites-Durham-University.h79455.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/f1a23f16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/40f303ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/7f82e6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/bf640df4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Duke Medical Center 4 km from Museum of Life and Science 8.4/10 Very good (1008) "Older property but very convenient and clean for our quick trip. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacie CA $180 CA $205 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=6066241&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Museum of Life and Science Hotel Reviews ![Holiday Inn Express Durham by IHG](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/b3df2a4a_y.jpg) ### Holiday Inn Express Durham by IHG 10/10 Excellent "Yes! Great" [](https://expedia.ca/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) ![University Inn Durham next to Duke University Medical Center](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/aaa7829c_y.jpg) ### University Inn Durham next to Duke University Medical Center 10/10 Excellent "This is an excellent hotel for the price. The staff was friendly, the room clean and comfortable, and the location is great. We will stay here in the future!" [](https://expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![Hampton Inn & Suites Durham/North I-85](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/cecacec2_y.jpg) ### Hampton Inn & Suites Durham/North I-85 10/10 Excellent "Short stay but very sayisfying" [](https://expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) ![The Lodge at Duke Medical Center](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/f1a23f16_y.jpg) ### The Lodge at Duke Medical Center 10/10 Excellent "Yes" [](https://expedia.ca/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information) ![21c Museum Hotel Durham](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/a66cf407_y.jpg) ### 21c Museum Hotel Durham 10/10 Excellent "Staff was very courteous " [](https://expedia.ca/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) ![Red Roof Inn Durham - Duke Univ Medical Center](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/eefd1cd6_y.jpg) ### Red Roof Inn Durham - Duke Univ Medical Center 10/10 Excellent "Clean room. Good location. " [](https://expedia.ca/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) ![Unscripted Durham, Part of JDV by Hyatt](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/0f9d6f74_y.jpg) ### Unscripted Durham, Part of JDV by Hyatt 10/10 Excellent "Nice" [](https://expedia.ca/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) ![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 10/10 Excellent "Only stayed one night. Everything good." [](https://expedia.ca/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown](https://images.trvl-media.com/lodging/73000000/72300000/72294900/72294847/745c2d84_y.jpg) ### Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown 10/10 Excellent "This property was a true gem! It was located in a cul-de-sac on a very quiet street very close to downtown Durham. I brought my children to visit colleges and this was a perfect home base. Everything was very clean, well appointed, the bedrooms were so comfortable and the outside space was absolutely a treat. Also, the host was extremely responsive and gave great recommendations on restaurants and area attractions. I would 100% recommend this property." [](https://expedia.ca/Durham-Hotels-Durham-Retreat-Deck.h72294847.Hotel-Information) ## Hotels near other Museum of Life and Science attractions [](https://www.expedia.ca/Brightleaf-Square-Hotels.0-l553248621532657772-0.Travel-Guide-Filter-Hotels) ### Brightleaf Square You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657772) [](https://www.expedia.ca/Vietnam-Veterans-Living-Memorial-Hotels.0-l553248621564886205-0.Travel-Guide-Filter-Hotels) ### Vietnam Veterans Living Memorial You can find out about the history of Durham with a visit to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886205) [](https://www.expedia.ca/Northgate-Mall-Hotels.0-l553248621564886206-0.Travel-Guide-Filter-Hotels) ### Northgate Mall You can find the perfect gifts to bring home at Northgate Mall during your trip to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886206) [](https://www.expedia.ca/Duke-Homestead-Hotels.0-l553248621532657783-0.Travel-Guide-Filter-Hotels) ### Duke Homestead Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657783) [](https://www.expedia.ca/Manbites-Dog-Theater-Hotels.0-l553248621564886210-0.Travel-Guide-Filter-Hotels) ### Manbites Dog Theater You can make plans for a show at Manbites Dog Theater during your trip to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886210) [](https://www.expedia.ca/Fullsteam-Brewery-Hotels.0-l553248621564886207-0.Travel-Guide-Filter-Hotels) ### Fullsteam Brewery You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886207) [](https://www.expedia.ca/Durham-Convention-Center-Hotels.0-l553248621532657774-0.Travel-Guide-Filter-Hotels) ### Durham Convention Center 4.2/5 (44 reviews) Learn about the events happening at Durham Convention Center during your trip to Durham. Discover the entertainment choices and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657774) [](https://www.expedia.ca/African-American-Dance-Ensemble-Hotels.0-l658956701486178304-0.Travel-Guide-Filter-Hotels) ### African American Dance Ensemble You can enjoy some culture when you stop by African American Dance Ensemble in Durham. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=658956701486178304) ## Frequently asked questions ### What's the area like around Museum of Life and Science? > Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 9 hotels and other accommodations you'll find within a mile. ### What's the best place to stay near Museum of Life and Science? > [Hampton Inn & Suites Durham/North I-85](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include [Red Roof Inn Durham - Duke Univ Medical Center](https://www.expedia.ca/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) and [Holiday Inn Express Durham by IHG](https://www.expedia.ca/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information). ### How many hotels will I find close to Museum of Life and Science? > Expedia has 9 hotels and other accommodations within a mile from Museum of Life and Science. ### If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund? > Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science. ### What can I see and do near Museum of Life and Science? > You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium. 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[Hotels near Durham Station](https://www.expedia.ca/Durham-Station-Hotels.d6194828.Travel-Guide-Hotels) - [Motels in Durham Station](https://www.expedia.ca/Durham-Station-Motels.d6194828-aaMotels.Travel-Guide-Accommodation) - [Hotels near Durham VA Medical Center](https://www.expedia.ca/Durham-VA-Medical-Center-Hotels.0-l6164731-0.Travel-Guide-Filter-Hotels) - [East Durham Hotels](https://www.expedia.ca/East-Durham-Raleigh-Hotels.0-n553248635976474768-0.Travel-Guide-Filter-Hotels) - [Hotels near Forest Hills Park](https://www.expedia.ca/Forest-Hills-Park-Hotels.0-l553248621564886204-0.Travel-Guide-Filter-Hotels) - [Gorman Hotels](https://www.expedia.ca/Gorman-Hotels.d553248634999204961.Travel-Guide-Hotels) - [Hayes Hotels](https://www.expedia.ca/Hayes-Raleigh-Hotels.0-n113656-0.Travel-Guide-Filter-Hotels) - [Lebanon Hotels](https://www.expedia.ca/Lebanon-Hotels.d553248635975867056.Travel-Guide-Hotels) - [Lowes Grove Hotels](https://www.expedia.ca/Lowes-Grove-Hotels.d3000008280.Travel-Guide-Hotels) - [Hotels near Nasher Museum of Art at Duke University](https://www.expedia.ca/Nasher-Museum-Of-Art-At-Duke-University-Hotels.0-l553248621532657768-0.Travel-Guide-Filter-Hotels) - [Hotels near North Carolina Central University](https://www.expedia.ca/North-Carolina-Central-University-Hotels.0-l6066245-0.Travel-Guide-Filter-Hotels) - [North Garrett Road Hotels](https://www.expedia.ca/North-Garrett-Road-Raleigh-Hotels.0-n553248635976478433-0.Travel-Guide-Filter-Hotels) - [Hotels near Northgate Mall](https://www.expedia.ca/Northgate-Mall-Hotels.0-l553248621564886206-0.Travel-Guide-Filter-Hotels) - [Hotels near Research Triangle Park](https://www.expedia.ca/Research-Triangle-Park-Hotels.0-l9677-0.Travel-Guide-Filter-Hotels) - [Hotels near Sarah P. Duke Gardens](https://www.expedia.ca/Sarah-P-Duke-Gardens-Hotels.0-l553248621532657769-0.Travel-Guide-Filter-Hotels) - [Hotels near Wallace Wade Stadium](https://www.expedia.ca/Wallace-Wade-Stadium-Hotels.0-l553248621564886201-0.Travel-Guide-Filter-Hotels) - [Woodcroft Hotels](https://www.expedia.ca/Woodcroft-Raleigh-Hotels.0-n553248635976473198-0.Travel-Guide-Filter-Hotels) - [Flights to Durham](https://www.expedia.ca/Cheap-Flights-To-Durham.d6049.Travel-Guide-Flights) - [Flights from Kitchener to Durham](https://www.expedia.ca/lp/flights/10579/6049/kitchener-to-durham) - [Flights from Atlanta to Durham](https://www.expedia.ca/lp/flights/178232/6049/atlanta-to-durham) - [Flights from Toronto to Durham](https://www.expedia.ca/lp/flights/178314/6049/toronto-to-durham) - [Flights from Kingston to Durham](https://www.expedia.ca/lp/flights/180034/6049/kingston-to-durham) - [Flights from Hamilton to Durham](https://www.expedia.ca/lp/flights/3963/6049/hamilton-to-durham) - [Flights from London to Durham](https://www.expedia.ca/lp/flights/4127/6049/london-to-durham) - [Durham Vacations](https://www.expedia.ca/Durham.d6049.Destination-Travel-Guides) - [Visit Durham](https://www.expedia.ca/Durham.dx6049) - [Northgate Mall](https://www.expedia.ca/Northgate-Mall-Raleigh.d553248621564886206.Vacation-Attraction) - [Avis Rental Cars in Durham](https://www.expedia.ca/Avis-Car-Rentals-In-Durham.d6049-c41.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Durham](https://www.expedia.ca/Budget-Car-Rentals-In-Durham.d6049-c39.Car-Rental-Guide-Suppliers) - [Car rental Durham](https://www.expedia.ca/Car-Rentals-In-Durham.d6049.Car-Rental-Guide) - [Car rentals near Northgate Mall](https://www.expedia.ca/Car-Rentals-In-Northgate-Mall.d553248621564886206.Car-Rental-Guide) - [Enterprise Rental Cars in Durham](https://www.expedia.ca/Enterprise-Car-Rentals-In-Durham.d6049-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Durham](https://www.expedia.ca/Hertz-Car-Rentals-In-Durham.d6049-c40.Car-Rental-Guide-Suppliers) - [Luxury Car Rentals in Durham](https://www.expedia.ca/Luxury-Car-Rentals-In-Durham.d6049-tLuxury.Car-Rental-Guide-Class) - [Pickup Car Rentals in Durham](https://www.expedia.ca/Pickup-Car-Rentals-In-Durham.d6049-tPickup.Car-Rental-Guide-Class) - [Suv Car Rentals in Durham](https://www.expedia.ca/SUV-Car-Rentals-In-Durham.d6049-tSUV.Car-Rental-Guide-Class) - [U-Save Rental Cars in Durham](https://www.expedia.ca/U-Save-Car-Rentals-In-Durham.d6049-c34.Car-Rental-Guide-Suppliers) - [Durham Vacation Rentals](https://www.expedia.ca/Durham-Vacation-Rentals.d6049.Travel-Guide-VacationRentals) - [Things to do in Durham](https://www.expedia.ca/Things-To-Do-In-Durham.d6049.Travel-Guide-Activities)