Title: Book the Best Mebane SPA Resorts from CA $277 - Spa Hotels in Mebane, NC | Expedia.ca [Hotels in Mebane](https://expedia.ca/Mebane-Hotels.d180961.Travel-Guide-Hotels)[Vacation Rentals in Mebane](https://expedia.ca/Mebane-Vacation-Rentals.d180961.Travel-Guide-VacationRentals)[Flights to Mebane](https://expedia.ca/Cheap-Flights-To-Mebane.d180961.Travel-Guide-Flights)[Mebane Car Rentals](https://expedia.ca/Car-Rentals-In-Mebane.d180961.Car-Rental-Guide)[Mebane Vacation Packages](https://expedia.ca/Mebane.d180961.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/pool.jpeg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Mebane, NC from CA $277 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mebane Spa Hotels Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-10-24&endDate=2025-10-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-10-25&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-10-24&endDate=2025-10-26&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-10-31&endDate=2025-11-02&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Mebane Spa Hotels ![Property amenity](https://images.trvl-media.com/lodging/108000000/107290000/107284700/107284695/1cb727cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/108000000/107290000/107284700/107284695/aac0aad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/108000000/107290000/107284700/107284695/d364fea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room, 1 King Bed, Mountain View](https://images.trvl-media.com/lodging/108000000/107290000/107284700/107284695/cf8c7a38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Virginia - A Caesars Rewards Destination Danville 8.4/10 Very good (108) "Staff were courteous and helpful very enjoyable stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) deborah CA $206 CA $296 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Danville-Hotels-Caesars-Virginia.h107284695.Hotel-Information) ![Aromatherapy, deep-tissue massages, Swedish massages, prenatal massages](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/e6835a24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/eec8c639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/d1e30aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/52832fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Durham Downtown Durham 8.4/10 Very good (1015) "Great staff and convenient location for us " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike CA $238 CA $277 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=180961&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Mebane Hotel Reviews ![Hilton Durham near Duke University](//images.trvl-media.com/lodging/1000000/20000/18900/18821/09c549f7_y.jpg) ### Hilton Durham near Duke University 10/10 Excellent "Everything was as expected" [](https://expedia.ca/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) ![Millennium Durham](//images.trvl-media.com/lodging/1000000/30000/26400/26351/309f8e95_y.jpg) ### Millennium Durham 10/10 Excellent "Wonderful. Will stay again!!!" [](https://expedia.ca/Raleigh-Hotels-Millennium-Durham.h26351.Hotel-Information) ![DoubleTree Suites by Hilton Raleigh - Durham](//images.trvl-media.com/lodging/1000000/20000/13200/13139/7fb5aa3f_y.jpg) ### DoubleTree Suites by Hilton Raleigh - Durham 10/10 Excellent "Very comfortable. Breakfast is a bit costly on the whole but I recommend the buffet. For the price of a fancy omelette you can fill your plate." [](https://expedia.ca/Raleigh-Hotels-DoubleTree-Suites-By-Hilton-Raleigh-Durham.h13139.Hotel-Information) ![Courtyard Durham Near Duke University/Downtown](//images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009_y.jpg) ### Courtyard Durham Near Duke University/Downtown 10/10 Excellent "Great stay." [](https://expedia.ca/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Comfort Inn & Suites Durham near Duke University](//images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 10/10 Excellent "Good security the only complaint is could not turn left out of property but great location." [](https://expedia.ca/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![SpringHill Suites by Marriott Durham Chapel Hill](//images.trvl-media.com/lodging/4000000/3530000/3525300/3525287/7dd298af_y.jpg) ### SpringHill Suites by Marriott Durham Chapel Hill 10/10 Excellent "Ok" [](https://expedia.ca/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-Chapel-Hill.h3525287.Hotel-Information) ![21c Museum Hotel Durham](//images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/a66cf407_y.jpg) ### 21c Museum Hotel Durham 10/10 Excellent "Unique hotel with great amenities, and a rotating art gallery. Within easy walking distance of multiple excellent restaurants and DPAC. " [](https://expedia.ca/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill](//images.trvl-media.com/lodging/1000000/170000/165800/165760/a2feecd0_y.jpg) ### La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill 10/10 Excellent "It was very clean and staff was friendly. Bed was comfortable " [](https://expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Mebane? > Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Enjoy the shopping and many popular restaurants during your vacation. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your holiday. ### What's there to see and do in Mebane? > Experience all that Mebane has to offer when you visit Tanger Outlet Center, Mill Creek, and Iron Gate Winery. If you have extra time while you're in the area, you might want to stop by Burlington Athletic Stadium and Occoneechee Mountain State Natural Area. ### What is a Mebane spa hotel? > Spa hotels in Mebane provide lodging and have a full on-site spa offering services like therapies and body treatments. Some also offer in-room treatments. 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