Title: Book the Best BUSINESS Hotels in Mebane in 2026 | Expedia.ca

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# Find Business Hotels in Mebane, NC from CA $135

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## Check availability on Mebane Business Hotels

Tonight

[Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Mebane business-friendly hotels

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904300/904203/91425190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904300/904203/c50bf7d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/910000/904300/904203/55574044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/910000/904300/904203/31b4ac7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Mebane by IHG

[](https://www.expedia.ca/Mebane-Hotels-Holiday-Inn-Express-Hotel-Suites-Mebane.h904203.Hotel-Information)

Mebane

8.2/10

Very good

(596)

"Clean room, friendly staff and the breakfast was superb!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cyrus Jean

CA $125

CA $141 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Mebane-Hotels-Holiday-Inn-Express-Hotel-Suites-Mebane.h904203.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/30000000/29450000/29443000/29442965/84c414a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/30000000/29450000/29443000/29442965/34dc0bab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/30000000/29450000/29443000/29442965/6c024599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/30000000/29450000/29443000/29442965/2f15ed4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Mebane

[](https://www.expedia.ca/Mebane-Hotels-Fairfield-Inn-Suites-By-Marriott-Mebane.h29442965.Hotel-Information)

Mebane

9.4/10

Exceptional

(469)

"A great place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Earvin

CA $154

CA $174 total

includes taxes & fees

Dec 25 - Dec 26

[](https://www.expedia.ca/Mebane-Hotels-Fairfield-Inn-Suites-By-Marriott-Mebane.h29442965.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/17000000/16240000/16238400/16238363/4b58cf20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/17000000/16240000/16238400/16238363/f8134c96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/17000000/16240000/16238400/16238363/072d9fd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/17000000/16240000/16238400/16238363/w2044h1535x0y6-3fc50fde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Acorn Suites

[](https://www.expedia.ca/Mebane-Hotels-The-Acorn-Suites.h16238363.Hotel-Information)

Mebane

9.6/10

Exceptional

(57)

"A wonderful place to stay, clean, hospitable and comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donald

CA $215

CA $242 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Mebane-Hotels-The-Acorn-Suites.h16238363.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/cecacec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/fcec797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/a3f8d81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 10:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/ae05b866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Durham/North I-85

[](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information)

Durham

9.0/10

Wonderful

(1004)

"Nice place to stay and close to everything. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christy

CA $146

CA $165 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/a7c0ffee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/f317395e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/02911e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/5058af4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Durham University Medical Center

[](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information)

Durham

9.6/10

Exceptional

(391)

"Great breakfast, clean rooms and beds "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Fabiola B

CA $151

CA $172 total

includes taxes & fees

Dec 26 - Dec 27

[](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/a2feecd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/8f63b9b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/adc70ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/b9a1e147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

[](https://www.expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information)

North Garrett Road

8.6/10

Excellent

(1794)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nicketta

CA $119

CA $135 total

includes taxes & fees

Dec 22 - Dec 23

[](https://www.expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information)

![Snack bar](https://images.trvl-media.com/lodging/72000000/71970000/71962600/71962512/14d0351c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/72000000/71970000/71962600/71962512/bfd7d857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/72000000/71970000/71962600/71962512/fb16e43f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/72000000/71970000/71962600/71962512/7b3ad97b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Chapel Hill

[](https://www.expedia.ca/Raleigh-Hotels-Tru-By-Hilton-Chapel-Hill.h71962512.Hotel-Information)

Chapel Hill

9.0/10

Wonderful

(684)

"The check in staff were great!!! The room was clean and the bed was nice. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Henry

CA $123

CA $140 total

includes taxes & fees

Jan 6 - Jan 7, 2026

[](https://www.expedia.ca/Raleigh-Hotels-Tru-By-Hilton-Chapel-Hill.h71962512.Hotel-Information)

![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/18500/18472/178b5fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/18500/18472/efbfc260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/18500/18472/b66d0dfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/20000/18500/18472/3e976603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Danville by IHG

[](https://www.expedia.ca/Danville-Hotels-Holiday-Inn-Express-Danville.h18472.Hotel-Information)

Danville

9.0/10

Wonderful

(604)

"The breakfast was amazing! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Towanda

CA $175

CA $204 total

includes taxes & fees

Jan 3 - Jan 4, 2026

[](https://www.expedia.ca/Danville-Hotels-Holiday-Inn-Express-Danville.h18472.Hotel-Information)

![Seasonal outdoor pool, open 10 AM to 9 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/920000/919700/919608/3a98f8b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/919700/919608/1219ae3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/920000/919700/919608/431f712f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/920000/919700/919608/7f88f4f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn & Suites Danville Hwy 58

[](https://www.expedia.ca/Danville-Hotels-Sleep-Inn-Suites-Danville-Hwy-58.h919608.Hotel-Information)

Danville

9.0/10

Wonderful

(722)

"The rooms were good, beds comfortable, and breakfast was good"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James

CA $163

CA $190 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/Danville-Hotels-Sleep-Inn-Suites-Danville-Hwy-58.h919608.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/67000000/66550000/66541300/66541217/118882ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/67000000/66550000/66541300/66541217/db89942e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Refrigerator & Microwave](https://images.trvl-media.com/lodging/67000000/66550000/66541300/66541217/94cd3fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/67000000/66550000/66541300/66541217/aa3e625f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Danville, VA

[](https://www.expedia.ca/Danville-Hotels-Hampton-Inn-Danville.h66541217.Hotel-Information)

Danville

9.0/10

Wonderful

(239)

"Staff was amazing !"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rachel

CA $134

CA $158 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Danville-Hotels-Hampton-Inn-Danville.h66541217.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02&regionId=180961&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Mebane Hotel Reviews

![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg)

### Comfort Inn & Suites Durham near Duke University

10/10 Excellent

"Front desk - Receptionist was pleasant "

[](https://expedia.ca/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information)

![Hampton Inn & Suites Chapel Hill/Durham, Area](https://images.trvl-media.com/lodging/1000000/290000/282000/281935/3ea796cb_y.jpg)

### Hampton Inn & Suites Chapel Hill/Durham, Area

10/10 Excellent

"People are genuinely nice"

[](https://expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Chapel-HillDurham.h281935.Hotel-Information)

![Hilton Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/09c549f7_y.jpg)

### Hilton Durham near Duke University

10/10 Excellent

"Everything was worth 5stars"

[](https://expedia.ca/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/a2feecd0_y.jpg)

### La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill

10/10 Excellent

"Great stay"

[](https://expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information)

![SpringHill Suites by Marriott Durham Chapel Hill](https://images.trvl-media.com/lodging/4000000/3530000/3525300/3525287/7dd298af_y.jpg)

### SpringHill Suites by Marriott Durham Chapel Hill

10/10 Excellent

"Great check in experience & room was spotless"

[](https://expedia.ca/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-Chapel-Hill.h3525287.Hotel-Information)

![University Inn Durham next to Duke University Medical Center](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/aaa7829c_y.jpg)

### University Inn Durham next to Duke University Medical Center

10/10 Excellent

"The room was large and exceptionally clean. The staff were courteous and the van drivers were friendly and arrived on time. This is a great placecto stay near the medical and nursing campus."

[](https://expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information)

![DoubleTree Suites by Hilton Raleigh - Durham](https://images.trvl-media.com/lodging/1000000/20000/13200/13139/7fb5aa3f_y.jpg)

### DoubleTree Suites by Hilton Raleigh - Durham

10/10 Excellent

"Staff was very courteous and helpful. Suite was very roomy. Location was excellent for us. Enjoyed using the fitness center"

[](https://expedia.ca/Raleigh-Hotels-DoubleTree-Suites-By-Hilton-Raleigh-Durham.h13139.Hotel-Information)

![Washington Duke Inn & Golf Club](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/fb0066de_y.jpg)

### Washington Duke Inn & Golf Club

10/10 Excellent

"Everything fabulous!"

[](https://expedia.ca/Raleigh-Hotels-Washington-Duke-Inn-Golf-Club.h10844.Hotel-Information)

![The Lodge at Duke Medical Center](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/f1a23f16_y.jpg)

### The Lodge at Duke Medical Center

10/10 Excellent

"Our room was great. Staff was super nice. Great location. "

[](https://expedia.ca/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information)

## Frequently asked questions

### How much do business-friendly hotels in Mebane cost?

### What are the best business-friendly hotels in Mebane?

### How many business-friendly hotels are there in Mebane?

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### Why book your business-friendly hotel in Mebane with Expedia?

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