Title: Book the Best CHEAP Hotels in Mayo River, VA  - Mayo River Cheap Hotels | Expedia.ca

[Mayo River Travel Guide](https://expedia.ca/Mayo-River.dx553248635976006279)[Hotels in Mayo River](https://expedia.ca/Mayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels)[Vacation Rentals in Mayo River](https://expedia.ca/Mayo-River-Vacation-Rentals.d553248635976006279.Travel-Guide-VacationRentals)[Flights to Mayo River](https://expedia.ca/Cheap-Flights-To-Mayo-River.d553248635976006279.Travel-Guide-Flights)[Mayo River Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-River.d553248635976006279.Car-Rental-Guide)[Mayo River Vacation Packages](https://expedia.ca/Mayo-River.d553248635976006279.Destination-Travel-Guides)

![The Reynolds Homestead, built in 1943 is in a beautiful foothill setting. Hardin Reynolds and his wife produced 16 children here, the most famous being RJ Reynolds who migrated to Winston Salem, NC to start the tobacco empire of the same name. The catalpa tree in the foreground still remains from the earliest days of the homestead.](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Ed Mayfield

# Find Cheap Hotels in Mayo River, VA 

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## Check availability on Mayo River Cheap Hotels

Tonight

[Dec 21 - Dec 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976006279&startDate=2025-12-21&endDate=2025-12-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property)

Tomorrow

[Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976006279&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976006279&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property)

In two weeks

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976006279&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=budget_property)

## Top Mayo River Hotel Reviews

![Travelodge by Wyndham Ridgeway Martinsville Area](https://images.trvl-media.com/lodging/1000000/20000/10900/10801/35d81c0c_y.jpg)

### Travelodge by Wyndham Ridgeway Martinsville Area

10/10 Excellent

"Great room"

[](https://expedia.ca/Martinsville-Hotels-Travelodge-By-Wyndham-Ridgeway-Martinsville-Area.h10801.Hotel-Information)

![Econo Lodge Martinsville](https://images.trvl-media.com/lodging/1000000/20000/12800/12704/9373a79c_y.jpg)

### Econo Lodge Martinsville

10/10 Excellent

"It's been my husband and my spot to get away from home for a little time to ourselves."

[](https://expedia.ca/Martinsville-Hotels-Econo-Lodge.h12704.Hotel-Information)

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