Title: Mayo Clinic Florida in Jacksonville - Tours and Activities | Expedia.ca [Mayo Clinic Florida Hotels](https://expedia.ca/Mayo-Clinic-Florida-Hotels.0-l6127706-0.Travel-Guide-Filter-Hotels)[Flights to Jacksonville](https://expedia.ca/Cheap-Flights-To-Jacksonville.d602997.Travel-Guide-Flights)[Things to do in Jacksonville](https://expedia.ca/Things-To-Do-In-Jacksonville.d602997.Travel-Guide-Activities)[Mayo Clinic Florida Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo-Clinic-Florida.d6127706.Car-Rental-Guide)[Jacksonville Vacation Packages](https://expedia.ca/Jacksonville.d602997.Destination-Travel-Guides) # Mayo Clinic Florida Tours and Activities ![Jacksonville_MayoClinicFlorida_6127706_04](https://images.trvl-media.com/place/6127706/6901ae4a-327b-40c7-92f0-e912ea036578.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mayo Clinic Florida](https://images.trvl-media.com/place/1674/ff36dd76-37b9-42ae-b52f-1d2de567c1a6.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mayo Clinic Florida](https://images.trvl-media.com/place/1674/24525ca6-f687-4913-a18c-ec870cf42632.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Mayo Clinic Florida](https://images.trvl-media.com/place/1674/34ed20de-d7f2-4282-a622-a16f9bef1701.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Mayo Clinic Florida Activities [Jacksonville travel guide](https://expedia.ca/Jacksonville.dx602997) --- --- ## Plan a trip to see Mayo Clinic Florida Price found within the past 48 hours. Click for updated prices. ![Delta Hotels by Marriott™ Jacksonville Deerwood](https://images.trvl-media.com/lodging/1000000/20000/17100/17002/c0129880_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Delta Hotels by Marriott™ Jacksonville Deerwood Southside CA $1,270 per person Apr 29 - May 4 found 1 day ago Roundtrip flight included Halifax (YHZ) to Jacksonville (JAX) 8.6/10 Excellent! (552 reviews) Friendly staff, comfortable beds. Reviewed on Mar 24, 2026 ![Hammock Beach Golf Resort & Spa](https://images.trvl-media.com/lodging/1000000/1000000/994200/994170/efacd58c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hammock Beach Golf Resort & Spa CA $1,368 per person May 20 - May 23 found 15 hours ago Roundtrip non-stop flight included Toronto (YYZ) to Daytona Beach (DAB) 8.6/10 Excellent! (1,010 reviews) The whole resort is top notch. Food, service, pools, staff… all 5 starts. Looking forward to our next trip. Reviewed on Mar 23, 2026 ![Hampton Inn Jacksonville Beach/Oceanfront](https://images.trvl-media.com/lodging/1000000/30000/26800/26716/c86000c3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn Jacksonville Beach/Oceanfront CA $1,654 per person Apr 29 - May 4 found 1 day ago Roundtrip flight included Halifax (YHZ) to Jacksonville (JAX) 9.2/10 Wonderful! (2,670 reviews) Breakfast and service was great. The jets in the hot tub didn't work, and the carpet in the room was all stained. Over all it wasn't bad. Didn't like paying $20 a night for my car to be in the parking lot. Reviewed on Mar 27, 2026 ### Popular places to visit ![Beach access, Huguenot Memorial Park in Duval County, Atlantic Ocean, Florida](https://images.trvl-media.com/place/553248621558033368/c8f597db-a1d5-4eee-bca9-4c53a802b60e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Huguenot Park Huguenot Park is just one of the places to see in Jacksonville Beach, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene and entertainment choices in this family-friendly area. [](https://expedia.ca/Huguenot-Park-Jacksonville.d553248621558033368.Vacation-Attraction) ![Miami beach, Florida lifeguard building hut by Atlantic ocean coast at sunrise with nobody on sand and still water reflection](https://images.trvl-media.com/place/553248635056397210/29db297c-3780-446c-b2df-31e281f679e5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Oceanfront Park 4/5(2 reviews) Explore the great outdoors at Oceanfront Park, a lovely green space in Jacksonville Beach. Experience the area's entertainment choices and acclaimed theater scene. [](https://expedia.ca/Oceanfront-Park-Jacksonville.d553248635056397210.Vacation-Attraction) #### Windsor Parke Golf Club Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event. [](https://expedia.ca/Windsor-Parke-Golf-Club-Jacksonville.d6068663.Vacation-Attraction) #### Windsor Commons Shopping Center You can enjoy retail therapy at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theater scene and great live music. [](https://expedia.ca/Windsor-Commons-Shopping-Center-Southside.d553248621558033805.Vacation-Attraction) #### Harbor City Municipal Golf Course Enjoy a round of golf in Jacksonville at Harbor City Municipal Golf Course. Amble around the area's beautiful beaches or attend a sporting event. [](https://expedia.ca/Harbor-City-Municipal-Golf-Course-Southside.d553248621563220206.Vacation-Attraction) #### Cradle Creek Preserve Explore the great outdoors at Cradle Creek Preserve, a lovely green space in Jacksonville Beach. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants. [](https://expedia.ca/Cradle-Creek-Preserve-Jacksonville.d553248621561766841.Vacation-Attraction) --- ## Best Lodging Options Near Mayo Clinic Florida ## Check availability on hotels close to Mayo Clinic Florida [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6127706&startDate=2026-03-27&endDate=2026-03-28)[Mar 27 - Mar 28](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6127706&startDate=2026-03-27&endDate=2026-03-28) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6127706&startDate=2026-03-28&endDate=2026-03-29)[Mar 28 - Mar 29](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6127706&startDate=2026-03-28&endDate=2026-03-29) [This weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6127706&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[Mar 27 - Mar 29](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=6127706&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) ![Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches](https://images.trvl-media.com/lodging/1000000/20000/19700/19631/7dde0660_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches 14390 Mayo Boulevard Jacksonville FL [](https://expedia.ca/Jacksonville-Hotels-Courtyard-By-Marriott-Jacksonville-At-Mayo-Clinic-CampusBeaches.h19631.Hotel-Information) ![Hilton Jacksonville At Mayo Clinic](https://images.trvl-media.com/lodging/117000000/116230000/116226000/116225907/b2da11bc_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Jacksonville At Mayo Clinic 4745 Transformation Way Jacksonville FL [](https://expedia.ca/Jacksonville-Hotels-Hilton-Jacksonville-At-Mayo-Clinic.h116225907.Hotel-Information) ![Margaritaville Jacksonville Beach](https://images.trvl-media.com/lodging/52000000/51270000/51266300/51266293/d30ef697_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Margaritaville Jacksonville Beach 715 1st St N Jacksonville Beach FL [](https://expedia.ca/Jacksonville-Hotels-Margaritaville-Jacksonville-Beach.h51266293.Hotel-Information) ![Residence Inn By Marriott Jacksonville - Mayo Clinic Area](https://images.trvl-media.com/lodging/60000000/59850000/59846400/59846313/b5b95b3d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Residence Inn By Marriott Jacksonville - Mayo Clinic Area 4905 SAN PABLO ROAD SOUTH Jacksonville FL [](https://expedia.ca/Jacksonville-Hotels-Residence-Inn-By-Marriott-Jacksonville-East.h59846313.Hotel-Information) ![Light Grey Getaway under 2 miles to mayo, 4 miles to the beach](https://images.trvl-media.com/lodging/43000000/42490000/42482300/42482256/c5a4eb75_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Light Grey Getaway under 2 miles to mayo, 4 miles to the beach Jacksonville FL [](https://expedia.ca/Jacksonville-Hotels-Vrbo-Property.h42482256.Hotel-Information) ![New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach](https://images.trvl-media.com/lodging/118000000/117050000/117041900/117041879/2b1a86aa_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### New 2 miles 2Mayo Clinic Intracoastal water views Mins to JaxBeach Jacksonville FL [](https://expedia.ca/Jacksonville-Hotels-New-2-Miles-2Mayo-Clinic-Intracoastal-Water-Views-Mins-To-JaxBeach.h117041879.Hotel-Information) ![Spacious 4-bedroom house in marvelous Jacksonville with AC](https://images.trvl-media.com/lodging/126000000/125260000/125253600/125253536/w1200h801x0y1-e6289f26_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Spacious 4-bedroom house in marvelous Jacksonville with AC Jacksonville FL [](https://expedia.ca/Jacksonville-Hotels-Spacious-4-Bedroom-House-In-Marvelous-Jacksonville-With-AC.h125253536.Hotel-Information) ![Family-Friendly Jax Beach Retreat with Heated Pool](https://images.trvl-media.com/lodging/84000000/83060000/83055800/83055766/5929a46f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Family-Friendly Jax Beach Retreat with Heated Pool Jacksonville Beach FL [](https://expedia.ca/Jacksonville-Hotels-1-Mi-To-Mayo-Private-Heated-Pool-5-Mins-To-Beach.h83055766.Hotel-Information) ![Comfy Mayo Retreat; Heated Pool, Close to Beach](https://images.trvl-media.com/lodging/68000000/67200000/67195700/67195679/5cb6747d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfy Mayo Retreat; Heated Pool, Close to Beach Jacksonville Beach FL [](https://expedia.ca/Jacksonville-Hotels-Intracoastal-Paradise-With-Private-Pool.h67195679.Hotel-Information) [See all 1,842 properties in Mayo Clinic Florida](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6127706) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.