Title: 10 Best Hotels in La Misión, Acuña for 2026 | Expedia.ca [Vacation Rentals in Acuña](https://expedia.ca/Acuna-Vacation-Rentals.d602273.Travel-Guide-VacationRentals)[Flights to Acuña](https://expedia.ca/Cheap-Flights-To-Acuna.d602273.Travel-Guide-Flights)[La Misión Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mision.d553248635976399648.Car-Rental-Guide)[La Misión Vacations](https://expedia.ca/La-Mision.d553248635976399648.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in La Misión, Acuña - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 3 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976399648&startDate=2026-01-03&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 4 - Jan 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976399648&startDate=2026-01-04&endDate=2026-01-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976399648&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=553248635976399648&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for La Misión hotels ![Interior](https://images.trvl-media.com/lodging/84000000/83230000/83221200/83221180/e6df999e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Suite, 1 Queen Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/84000000/83230000/83221200/83221180/ebb2b674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/84000000/83230000/83221200/83221180/2dadfac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83230000/83221200/83221180/4e6b9ccb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palms Suites [](https://www.expedia.ca/Acuna-Hotels-CMG-Suites.h83221180.Hotel-Information) 9.6 km from La Misión 9.0/10 Wonderful (31) "Clean, comfortable and very helpful front desk" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rocky [](https://www.expedia.ca/Acuna-Hotels-CMG-Suites.h83221180.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/125000000/124400000/124393700/124393676/a2b1bfe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/125000000/124400000/124393700/124393676/0e635264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/125000000/124400000/124393700/124393676/5c1ba481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124393700/124393676/b14db276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamento MateoS [](https://www.expedia.ca/Acuna-Hotels-Departamento-MateoS.h124393676.Hotel-Information) 5.1 km from La Misión CA $100 CA $119 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Acuna-Hotels-Departamento-MateoS.h124393676.Hotel-Information) ![Dining room](https://images.trvl-media.com/lodging/125000000/124400000/124395700/124395622/531828ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124395700/124395622/74382a4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort House, Patio | Terrace/patio](https://images.trvl-media.com/lodging/125000000/124400000/124395700/124395622/48f6147f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort House, Patio](https://images.trvl-media.com/lodging/125000000/124400000/124395700/124395622/15e5a3a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamentos MateoS 504 [](https://www.expedia.ca/Acuna-Hotels-Departamentos-MateoS-504.h124395622.Hotel-Information) 8 km from La Misión CA $100 CA $119 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Acuna-Hotels-Departamentos-MateoS-504.h124395622.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/4f1ee5d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/c09e15c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/03b4e634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124395400/124395307/bbcdb682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamento MateoS 503 [](https://www.expedia.ca/Acuna-Hotels-Departamento-MateoS-503.h124395307.Hotel-Information) 5.1 km from La Misión CA $100 CA $119 total includes taxes & fees Jan 5 - Jan 6 [](https://www.expedia.ca/Acuna-Hotels-Departamento-MateoS-503.h124395307.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/83667014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/f0672d39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/a6bd5107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/125000000/124400000/124395200/124395132/abdb940e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Departamentos MateoS 504 [](https://www.expedia.ca/Acuna-Hotels-Departamentos-MateoS-504.h124395132.Hotel-Information) 5.1 km from La Misión CA $107 CA $128 total includes taxes & fees Jan 9 - Jan 10 [](https://www.expedia.ca/Acuna-Hotels-Departamentos-MateoS-504.h124395132.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-18&endDate=2026-01-19®ionId=553248635976399648&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top La Misión Hotel Reviews ![Palms Suites](https://images.trvl-media.com/lodging/84000000/83230000/83221200/83221180/e6df999e_y.jpg) ### Palms Suites 10/10 Excellent "Our stay was very pleasant. Very peaceful and felt so secured. We’ll be back to book this place again for sure! " [](https://expedia.ca/Acuna-Hotels-CMG-Suites.h83221180.Hotel-Information) ## Frequently asked questions ### What is La Misión like? ### If I need to cancel my hotel reservation in La Misión, will I receive a refund? ### What are the top things to see and do in La Misión? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hilton Hotels in Acuña ](https://www.expedia.ca/Acuna-Hotels-Hilton-Hotels.0-0-d602273--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Acuña Hotels ](https://www.expedia.ca/Acuna-Hotels.d602273.Travel-Guide-Hotels) - [Allende Hotels ](https://www.expedia.ca/Allende-Hotels.d553248635640642434.Travel-Guide-Hotels) - [Morelos Hotels ](https://www.expedia.ca/Morelos-Hotels.d3000425951.Travel-Guide-Hotels) - [Múzquiz Hotels ](https://www.expedia.ca/Muzquiz-Hotels.d553248635640633654.Travel-Guide-Hotels) - [Nava Hotels ](https://www.expedia.ca/Nava-Hotels.d553248635640673651.Travel-Guide-Hotels) - [Piedras Negras Hotels ](https://www.expedia.ca/Piedras-Negras-Hotels.d6052600.Travel-Guide-Hotels) - [Villa Unión Hotels ](https://www.expedia.ca/Villa-Union-Hotels.d553248635640678083.Travel-Guide-Hotels) - [Flights to Acuña ](https://www.expedia.ca/Cheap-Flights-To-Acuna.d602273.Travel-Guide-Flights) - [Flights from Buffalo (BUF) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/buf/pds/buffalo-to-piedras-negras) - [Flights from Colima (CLQ) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/clq/pds/colima-to-piedras-negras) - [Flights from Houston (IAH) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/iah/pds/houston-to-piedras-negras) - [Flights from Sacramento (SMF) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/smf/pds/sacramento-to-piedras-negras) - [Flights from Montreal (YUL) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/yul/pds/montreal-to-piedras-negras) - [Flights from Vancouver (YVR) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/yvr/pds/vancouver-to-piedras-negras) - [Flights from Saskatoon (YXE) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/yxe/pds/saskatoon-to-piedras-negras) - [Flights from Toronto (YYZ) to Piedras Negras (PDS) ](https://www.expedia.ca/lp/flights/yyz/pds/toronto-to-piedras-negras) - [Acuña Vacations ](https://www.expedia.ca/Acuna.d602273.Destination-Travel-Guides) - [Piedras Negras Vacations ](https://www.expedia.ca/Piedras-Negras.d6052600.Destination-Travel-Guides) - [Visit Piedras Negras ](https://www.expedia.ca/Piedras-Negras.dx6052600) - [Car rental Piedras Negras ](https://www.expedia.ca/Car-Rentals-In-Piedras-Negras.d6052600.Car-Rental-Guide) - [Book Hotels in La Misión on Expedia.mx ](https://www.expedia.mx/La-Mision-Acuna-Hoteles.0-n553248635976399648-0.Guia-Viajes-Filter-Hoteles)