Title: Visit La Mesilla: Best of La Mesilla Tourism | Expedia Travel Guide - Expedia.ca [Hotels in La Mesilla](https://expedia.ca/La-Mesilla-Hotels.d553248635975872198.Travel-Guide-Hotels)[Vacation Rentals in La Mesilla](https://expedia.ca/La-Mesilla-Vacation-Rentals.d553248635975872198.Travel-Guide-VacationRentals)[La Mesilla Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesilla.d553248635975872198.Car-Rental-Guide)[La Mesilla Vacation Packages](https://expedia.ca/La-Mesilla.d553248635975872198.Destination-Travel-Guides) # La Mesilla ## Travel Guide ## Visit La Mesilla Things to do - La Mesilla Hotel Deals - Vacation Rentals in La Mesilla ![Hilton Santa Fe Buffalo Thunder](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Santa Fe Buffalo Thunder 20 Buffalo Thunder Trl, Santa Fe, NM Fully refundableReserve now, pay when you stay CA $163 CA $186 total Nov 13 - Nov 14 includes taxes & fees Stay at this 4-star spa resort in Santa Fe. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the clean rooms ... 8.4/10 Very Good! (1,050 reviews) It was nice. Reviewed on Oct 20, 2025 [](https://expedia.ca/Hotel-Search?startDate=13%2F11%2F2025&endDate=14%2F11%2F2025&selected=2058957&PinnedHotelID=2058957&HadPinnedHotel=true®ionId=553248635975872198) ![Cities Of Gold Casino](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cities Of Gold Casino 10-A Cities of Gold Road, Santa Fe, NM CA $112 CA $128 total Nov 16 - Nov 17 includes taxes & fees Stay at this 3-star business-friendly hotel in Santa Fe. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean rooms ... 8/10 Very Good! (1,047 reviews) Room was very clean, staff was friendly and helpful, didn't go to the casino. In the morn, no coffee. Pots were empty. Reviewed on Oct 19, 2025 [](https://expedia.ca/Hotel-Search?startDate=16%2F11%2F2025&endDate=17%2F11%2F2025&selected=120761&PinnedHotelID=120761&HadPinnedHotel=true®ionId=553248635975872198) ![Hotel Glorieta](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/951776db_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Glorieta 750 N. St Francis Dr, Santa Fe, NM Fully refundableReserve now, pay when you stay CA $138 CA $200 total Nov 13 - Nov 14 includes taxes & fees Stay at this 3.5-star business-friendly hotel in Santa Fe. Enjoy an outdoor pool, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ... 7.8/10 Good! (1,012 reviews) Property was close to square and railyard. Reviewed on Oct 18, 2025 [](https://expedia.ca/Hotel-Search?startDate=13%2F11%2F2025&endDate=14%2F11%2F2025&selected=3139&PinnedHotelID=3139&HadPinnedHotel=true®ionId=553248635975872198) [See all 305 properties in La Mesilla](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F10%2F2025&endDate=26%2F10%2F2025®ionId=553248635975872198) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Dreamy Home Meets Historic Charm](https://images.trvl-media.com/lodging/112000000/111560000/111557200/111557186/fbecb669_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Dreamy Home Meets Historic Charm Los Alamos Stay at this vacation home in Los Alamos. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions Los Alamos Historical Museum and ... 9/10 Wonderful! (12 reviews) Perfect for family with young kids Reviewed on Oct 5, 2025 [](https://expedia.ca/Los-Alamos-Hotels-Dreamy-Home-Meets-Historic-Charm.h111557186.Hotel-Information) ![Vista La Sierra | Pet Friendly, Mountain View!](https://images.trvl-media.com/lodging/68000000/67630000/67628500/67628492/9945b31a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Vista La Sierra | Pet Friendly, Mountain View! Santa Fe Stay at this condo in Santa Fe. Enjoy laundry facilities, patios, and cable/satellite TV service. Popular attractions Santa Fe Plaza and Meow Wolf are located ... 9.4/10 Exceptional! (151 reviews) The property was amazing! Communication through the entire process was fantastic. Truly the only not perfect item is we could hear the interstate which kept us from using the extremely scenic balcony. Now, that said, the location also made it extremely easy to get to everywhere we needed to go. I ... Reviewed on Sep 27, 2025 [](https://expedia.ca/Santa-Fe-Hotels-Vista-La-Sierra-Pet-Friendly.h67628492.Hotel-Information) ![Visitors Love the Location, I Love the View!](https://images.trvl-media.com/lodging/28000000/27490000/27489100/27489064/83009d59_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Visitors Love the Location, I Love the View! Santa Fe Book a stay at this ski condo in Santa Fe. Enjoy free WiFi, laundry facilities, and ski-in/ski-out access. Our guests praise the helpful staff in our reviews. ... 9.8/10 Exceptional! (387 reviews) Lovely condo in a great location. Check in and out very easy and host had several helpful suggestions. We would definitely return. Reviewed on Sep 12, 2025 [](https://expedia.ca/Santa-Fe-Hotels-Mountain-View-Plus-A-Perfect-Location.h27489064.Hotel-Information) [See all properties in La Mesilla](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635975872198&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check La Mesilla hotel availability [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-24&endDate=2025-10-25) [Tonight](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-24&endDate=2025-10-25) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-24&endDate=2025-10-25) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-24&endDate=2025-10-25)[Oct 24 - Oct 25](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-24&endDate=2025-10-25) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-25&endDate=2025-10-26) [Tomorrow night](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-25&endDate=2025-10-26) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-25&endDate=2025-10-26) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-25&endDate=2025-10-26)[Oct 25 - Oct 26](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=2025-10-25&endDate=2025-10-26) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [This weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025)[Oct 24 - Oct 26](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635975872198&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) ### Popular places to visit ![Puye Cliff Dwellings](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/186000/186922-Santa-Fe.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Puye Cliff Dwellings Learn about the Pueblo Indians from these cave dwellings carved into the side of a cliff and atop a large mesa in the Rio Grande Valley. [](https://expedia.ca/Puye-Cliff-Dwellings-Espanola.d6093711.Vacation-Attraction) #### Presbyterian Espanola Hospital Though Presbyterian Espanola Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Espanola while you are here. [](https://expedia.ca/Presbyterian-Espanola-Hospital-Santa-Fe.d624554668257513472.Vacation-Attraction) #### Tesuque Peak Trail You can take time to visit Tesuque Peak Trail during your travels to Espanola. Check out the casinos and top-notch restaurants in this relaxing area. [](https://expedia.ca/Tesuque-Peak-Trail-Espanola.d553248621532645936.Vacation-Attraction) ## Cities near La Mesilla ![Espanola which includes tranquil scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/169000/169811-Northern-New-Mexico.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Espanola [](https://expedia.ca/Espanola.dx7121) - Cities near La Mesilla - Places of interest [Espanola](https://expedia.ca/Espanola.dx7121) - [Santa Fe Opera](https://expedia.ca/Santa-Fe-Opera-Santa-Fe.d6064365.Vacation-Attraction) - [Bandelier National Monument](https://expedia.ca/Bandelier-National-Monument-New-Mexico.d6093677.Vacation-Attraction) - [Santuario de Chimayo](https://expedia.ca/Santuario-De-Chimayo-Chimayo.d6093681.Vacation-Attraction) - [Santa Fe National Cemetery](https://expedia.ca/Santa-Fe-National-Cemetery-Northeast-Santa-Fe.d553248621532645896.Vacation-Attraction) - [Puye Cliff Dwellings](https://expedia.ca/Puye-Cliff-Dwellings-Espanola.d6093711.Vacation-Attraction) - [Las Campanas Santa Fe](https://expedia.ca/Las-Campanas-Santa-Fe-Las-Campanas.d553248621532645817.Vacation-Attraction) - [Casa Cristal Pottery](https://expedia.ca/Casa-Cristal-Pottery-Velarde.d553248621532645863.Vacation-Attraction) - [Don Quixote Distillery & Winery](https://expedia.ca/Don-Quixote-Distillery-Winery-Los-Alamos.d553248621532645771.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)