Title: Kirksville Vacation Rentals from CA $141: Short-Term Rentals for 2026 | Expedia.ca

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![Thousand Hill State Park](https://images.trvl-media.com/place/1630/fc722898-84e8-4e1a-b266-b1ca1d792625.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=1630&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=1630&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=1630&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=1630&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Find vacation rentals that suit your style

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Kirksville%2C+Missouri%2C+United+States+of+America&regionId=1630&latLong=40.194756%2C-92.583252&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Kirksville%2C+Missouri%2C+United+States+of+America&regionId=1630&latLong=40.194756%2C-92.583252&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VACATION_HOME)

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## Top Kirksville Hotel Reviews

![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg)

### Hampton Inn Kirksville

10/10 Excellent

"Clean and welcoming hotel and room. Very helpful staff. Excellent stay."

[](https://expedia.ca/Macon-Hotels-Hampton-Inn-Kirksville.h19991846.Hotel-Information)

![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg)

### Super 8 by Wyndham Kirksville-University Area

10/10 Excellent

"Friendly staff, clean rooms, comfy beds and pillows. We always are greeted promptly and with a smile, no matter what time we arrive. We've switched our weekend trips to see family from the pricier hotels to the Super 8\. We get better service and great quality at a fraction of the price. "

[](https://expedia.ca/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information)

![Country Cabin In The Woods](https://images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg)

### Country Cabin In The Woods

10/10 Excellent

"Very cute and cozy little cabin. Scenery was beautiful. Highly recommend to anyone wanting a getaway in the Kirksville area."

[](https://expedia.ca/Kirksville-Hotels-Located-10-Minutes-From-Thousand-Hills-And-15-Minutes-From-Kirksville.h104308277.Hotel-Information)

![Days Inn by Wyndham Kirksville](https://images.trvl-media.com/lodging/1000000/10000/4100/4031/9821cb76_y.jpg)

### Days Inn by Wyndham Kirksville

10/10 Excellent

"Room was clean, organized. Staff was welcoming "

[](https://expedia.ca/Macon-Hotels-Days-Inn-By-Wyndham-Kirksville.h4031.Hotel-Information)

![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](https://images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/acd401ea_y.jpg)

### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville

10/10 Excellent

"Everything was excellent!"

[](https://expedia.ca/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information)

![Holiday Inn Express & Suites Kirksville - University Area by IHG](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649_y.jpg)

### Holiday Inn Express & Suites Kirksville - University Area by IHG

10/10 Excellent

"Everything was awesome."

[](https://expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information)

![Knights Inn Kirksville](https://images.trvl-media.com/lodging/1000000/30000/22200/22159/fa987a1d_y.jpg)

### Knights Inn Kirksville

10/10 Excellent

"Room was clean… quiet… "

[](https://expedia.ca/Macon-Hotels-Knights-Inn-Kirksville.h22159.Hotel-Information)

![New tiny home in an incredible private setting among all nature has to offer.](https://images.trvl-media.com/lodging/118000000/117030000/117029100/117029091/2899d4ac_y.jpg)

### New tiny home in an incredible private setting among all nature has to offer.

10/10 Excellent

"The host was extremely welcoming and communicated well. They had a stocked kitchen for us with food and coffee. "

[](https://expedia.ca/Kirksville-Hotels-New-Tiny-Home-In-An-Incredible-Private-Setting-Among-All-Nature-Has-To-Offer.h117029091.Hotel-Information)

![Quaint Guest Cottage](https://images.trvl-media.com/lodging/70000000/69550000/69540200/69540190/5569bd06_y.jpg)

### Quaint Guest Cottage

10/10 Excellent

"We loved this charming little cottage! Remodeled and decorated beautifully. It was clean and the bed was very comfortable. Kitchen and laundry room are an added convenience in addition to walking distance to Truman State University. "

[](https://expedia.ca/Kirksville-Hotels-House.h69540190.Hotel-Information)

## Find out more about Kirksville

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Kirksville. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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