Santo Domingo de los Tsáchilas Vacation Rentals from CA $63: Short-Term Rentals for 2026

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Our top choices for Santo Domingo de los Tsáchilas vacation rentals

A wooden-paneled bedroom with a bed, a chandelier, and a window with curtains.

1. Private Riverfront Cabin with Pool, Waterfall & Free Breakfast

Pedro Vicente Maldonado

CA $274 total

Nov 1 - Nov 2

A view of a pool area with a clear sky, surrounded by lush greenery and a covered seating area.

2. Charming 2-bedroom villa in superb Pedro Vicente Maldonado with WiFi

Pedro Vicente Maldonado

CA $214 total

Nov 1 - Nov 2

A resort with a swimming pool, a children's play area, and a covered seating area.

3. Perfect Weekend Retreat! Pool, Private BBQ & Nature - 2 Hours from Quito

Pedro Vicente Maldonado

CA $253 total

Nov 8 - Nov 9

A wooden structure with a balcony, surrounded by dense foliage.

4. La Cabañita del Viajero

Mindo

CA $114 total

Oct 31 - Nov 1

A rooftop pool with a slide, surrounded by lounge chairs and umbrellas, and a glass building to the left.

5. Torres de Suites by InAmazonas

Iñaquito

Geovanini

CA $192 total

Nov 21 - Nov 22

A wooden deck with a red table, a teapot, and a glass.

6. Treehouse

Solanda

"We truly enjoyed our stay at this little retreat just outside the city of Quito. The property manager was very attentive to our needs and informative about the surrounding areas. He gave us great tips on when and where to visit in and around the city with insider info given his life lived in the area. The donkey is actually a treat to have around as her and our dog became fast friends. If you want a quiet retreat to just relax and rest your head after long days visiting the city or several...

Sarah G.

CA $184 total

Nov 3 - Nov 4

A wooden deck with a hammock and a hanging lantern.

7. Perfect 4-bedroom cabin in adorable Mindo for nature lovers

Mindo

CA $70 total

Nov 1 - Nov 2

A traditional house with a tiled roof, wooden windows, and a stone foundation.

8. Charming Hacienda House with private forest in the heart of Nono

Parroquia Nono

CA $223 total

Nov 3 - Nov 4

A hammock under a wooden pergola, a small table with a chair, and lush greenery in the background.

9. Casa Búho - una casa en medio del bosque!!

quito

CA $168 total

Nov 1 - Nov 2

A modern building with balconies, large windows, and potted plants.

10. NOSTRA HOUSE

Quito

ANGEL R J.

CA $112 total

Nov 3 - Nov 4

A spacious courtyard with stone flooring, multiple seating areas, and a variety of potted plants.

11. Old Town Quito Suites, Apartments & Boutique hotel

Centro Histórico

Hong

CA $255 total

Oct 29 - Oct 30

A courtyard with a wooden balcony, potted plants, and hanging ferns.

12. Apart Hotel Loma Chica Quito

Quito Historic Center

Suma

CA $63 total

Oct 31 - Nov 1

A room with a large window, two grey sofas, a small wooden table, and a wall-mounted artwork.

13. Habitación Estudio en las Faldas del Volcán Pichincha

Miraflores

CA $63 total

Oct 29 - Oct 30

A bedroom with a wooden floor, a bed with patterned bedding, a small table, a potted plant, and a view of a cityscape through large windows.

14. Suite Centro Histórico

Quito Historic Center

CA $77 total

Oct 29 - Oct 30

An indoor courtyard with stone flooring, potted plants, and hanging ferns.

15. Casa Magica - Historic Luxury Villa in Quito Old Town

Quito Historic Center

"Staying at Casa Mágica exceeded all our expectations. The house itself is absolute perfection, even more beautiful, spacious, and inviting in person than in the pictures. It provided the ideal setting for us to gather, reconnect, and create wonderful memories with our Ecuadorian family. What truly sets this place apart, however, is the host team, they were beyond amazing. Their service, kindness, and genuine warmth made us feel completely cared for from start to finish. They were so...

Paulina

CA $739 total

Oct 31 - Nov 1

A dining area with a glass table, metal chairs, a wooden cabinet with glass doors, and a framed picture on the wall.

16. The Colonial Ship

Itchimbia

CA $71 total

Oct 29 - Oct 30

A view through an open door leading to a balcony with potted plants and hanging decorations.

17. Cozy Apartment, La Ronda, Historic Center

Quito Historic Center

CA $91 total

Oct 29 - Oct 30

A bedroom with a bed, a nightstand, a lamp, and a mirror on the wall.

18. The Colonel's House

Centro Histórico

CA $70 total

Oct 29 - Oct 30

A spacious living area with a wooden dining table, comfortable seating, a sofa with colorful cushions, and a staircase leading to another level.

19. La Ronda 431 - Apt. #107 (Duplex)

Quito Historic Center

david b.

CA $340 total

Oct 29 - Oct 30

A modern kitchen with a dining area, wooden flooring, and a large window.

20. La Ronda 431 - Apt. #106

Quito Historic Center

CA $269 total

Oct 29 - Oct 30

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Top Santo Domingo de los Tsáchilas Hotel Reviews

Vista del Angel Hotel Boutique

10/10 Excellent

"The locations is unique , our"

Hotel Casa Alquimia

10/10 Excellent

"This is a unique and fascinating hotel. Antiques, interesting collections and historical information displayed in glass cabinets on all 3 floors. Our room was large and decorated in a local theme. Breakfast was delicious and served on the roof top while taking in the amazing views of Quito. Highly recommend this hotel."

Friends Hotel & Rooftop - Historic Center & Museums

10/10 Excellent

"Lovely place to stay in Old Town. We were within walking distance of lots of museums, churches, food, and shopping. The staff was amazing--gave us help finding tourist spots and food and taking the subway (very clean and modern). The free breakfasts were excellent. Only caveat...you need to walk stairs to your rooms (bags were delivered/taken down, so that's covered). Quaint, quirky, and perfect."

Hotel Reina Isabel

10/10 Excellent

"Great hotel, had security and attentive staff. Breakfast included fresh fruit, breads, porridge and fresh orange juice. Room was quite spacious with large bathroom. Plaza Grande and historic area is 15 min taxi ride away. Local area was unsafe at night; staff insisted on taxi rides to go anywhere after dark."

Find out more about Santo Domingo de los Tsáchilas

Everything you need to know about Santo Domingo de los Tsáchilas vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santo Domingo de los Tsáchilas vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santo Domingo de los Tsáchilas vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santo Domingo de los Tsáchilas vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santo Domingo de los Tsáchilas. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santo Domingo de los Tsáchilas vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santo Domingo de los Tsáchilas vacation rentals we have selected for you start as low as CA $63 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santo Domingo de los Tsáchilas rentals

At Expedia, we put the best Santo Domingo de los Tsáchilas vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santo Domingo de los Tsáchilas rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santo Domingo de los Tsáchilas vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santo Domingo de los Tsáchilas. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Room 1

Change your mind

Treat yourself

Be picky

Our top choices for Santo Domingo de los Tsáchilas vacation rentals

1. Private Riverfront Cabin with Pool, Waterfall & Free Breakfast

2. Charming 2-bedroom villa in superb Pedro Vicente Maldonado with WiFi

3. Perfect Weekend Retreat! Pool, Private BBQ & Nature - 2 Hours from Quito

4. La Cabañita del Viajero

5. Torres de Suites by InAmazonas

6. Treehouse

7. Perfect 4-bedroom cabin in adorable Mindo for nature lovers

8. Charming Hacienda House with private forest in the heart of Nono

9. Casa Búho - una casa en medio del bosque!!

10. NOSTRA HOUSE

11. Old Town Quito Suites, Apartments & Boutique hotel

12. Apart Hotel Loma Chica Quito

13. Habitación Estudio en las Faldas del Volcán Pichincha

14. Suite Centro Histórico

15. Casa Magica - Historic Luxury Villa in Quito Old Town

16. The Colonial Ship

17. Cozy Apartment, La Ronda, Historic Center

18. The Colonel's House

19. La Ronda 431 - Apt. #107 (Duplex)

20. La Ronda 431 - Apt. #106

Find vacation rentals that suit your style

Top Santo Domingo de los Tsáchilas Hotel Reviews

Vista del Angel Hotel Boutique

Rossa Mia Hotel Boutique

Hotel Casa Alquimia

Friends Hotel & Rooftop - Historic Center & Museums

Hilton Colon Quito

Hotel San Francisco de Quito

Hotel La Basílica Quito

Hotel Reina Isabel

Secret Garden - Hostel

Find out more about Santo Domingo de los Tsáchilas