Search Lafayette County Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Lafayette County hotels
1. Suwannee River Rendezvous
Suwannee River RendezvousMayo
8.6 out of 10, Excellent, (33 reviews)
"This is a lovely place to visit"
Beth
The price is CA $125
CA $167 total
includes taxes & fees
Aug 24 - Aug 25
2. Cindys Motel
Cindys MotelMayo
8.8 out of 10, Excellent, (137 reviews)
"wonderful, quiet, a hide a way for a fun stay"
Diane
The price is CA $122
CA $132 total
includes taxes & fees
Sep 10 - Sep 11
3. Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,Mayo
10.0 out of 10, Exceptional, (14 reviews)
"Fantastic property very quiet with very friendly animals."
Hevrard
The price is CA $61
CA $115 total
includes taxes & fees
Aug 22 - Aug 23
4. Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent campingMayo
9.8 out of 10, Exceptional, (15 reviews)
"Had a great weekend away- it was just what me and my girlfriend needed."
Mike S.
The price is CA $67
CA $129 total
includes taxes & fees
Aug 20 - Aug 21
5. RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower houseMayo
10.0 out of 10, Exceptional, (6 reviews)
"Love this little slice of heaven!"
Crystal
The price is CA $76
CA $109 total
includes taxes & fees
Aug 29 - Aug 30
6. Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe RiverBranford
10.0 out of 10, Exceptional, (12 reviews)
"Hosts are awesome, and there's enough amenities to keep any family busy for as long as they'd like. "
James S.
The price is CA $174
CA $344 total
includes taxes & fees
Aug 18 - Aug 19
7. Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit
Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pitMayo
10.0 out of 10, Exceptional, (83 reviews)
"Could use some cleaning but it was perfect"
Olivia
8. Ichetucknee Springs/Ginnie Springs/Santa Fe River at the Hideaway Cottage
Ichetucknee Springs/Ginnie Springs/Santa Fe River at the Hideaway CottageBranford
10.0 out of 10, Exceptional, (125 reviews)
"Loved our visit. The owners were accommodating and informative about the area. As Florida residents, this will be a regular visit."
Rick F.
9. Enzo's Retreat. 6 minutes to Ichetucknee Springs! Family friendly
Enzo's Retreat. 6 minutes to Ichetucknee Springs! Family friendlyBranford
8.8 out of 10, Excellent, (17 reviews)
"We had a great time. Awesome location, cute place, clean and comfortable. Easy to check in. Would definitely stay again!"
Virginia
10. Private 12 acre Ranch sleeps up to 8 on The Santa Fe River.
Private 12 acre Ranch sleeps up to 8 on The Santa Fe River.high springs
9.8 out of 10, Exceptional, (93 reviews)
"What a great spot. The river is beautiful and right there. Centrally located to High Springs and ichetucknee springs. Owner is very accommodating and house is well stocked with toys. Will be going back. "
Daniel R.
11. 3 Rivers Getaway
3 Rivers GetawayBranford
10.0 out of 10, Exceptional, (1 review)
"Was a wonderful experience "
Kim S.
12. Cozy Log Cabin Retreat on the Santa Fe River – Nature, Kayaking & Relaxation!
Cozy Log Cabin Retreat on the Santa Fe River – Nature, Kayaking & Relaxation!Branford
10.0 out of 10, Exceptional, (28 reviews)
"The cabin was so clean, cozy, and the perfect place for a relaxing weekend away! "
Grayson C.
13. Butterfly Crossing peaceful getaway on the historic Suwannee. Fish, Boat, Relax
Butterfly Crossing peaceful getaway on the historic Suwannee. Fish, Boat, RelaxBranford
9.8 out of 10, Exceptional, (20 reviews)
"This is our 3rd year staying and it is always a great experience. The property is well maintained and the view and dock are great. "
Stephanie M.
14. Beautiful, wooded campsite in Branford, FL perfect for outdoor adventures
Beautiful, wooded campsite in Branford, FL perfect for outdoor adventuresBranford
15. The Best memories are made on the Suwannee River
The Best memories are made on the Suwannee RiverMayo
9.8 out of 10, Exceptional, (57 reviews)
"Was there for a family reunion and was great for what we needed."
Anonymous traveller
The price is CA $187
CA $389 total
includes taxes & fees
Sep 12 - Sep 13
16. The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee
The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet feeBranford
10.0 out of 10, Exceptional, (72 reviews)
"We loved it!"
Shane Z.
17. Wonderful Vacation Home For Making Memories
Wonderful Vacation Home For Making MemoriesBranford
9.8 out of 10, Exceptional, (181 reviews)
"One of the most peaceful places we have ever stayed. Our entire family enjoyed our visit. The house is beautiful and the location is perfect. If you need a home to get away from your busy life - this is where you should go!"
Joella S.
18. Riverbend Retreat / Suwannee Riverfront/ Kayaks & Hot Tub
Riverbend Retreat / Suwannee Riverfront/ Kayaks & Hot TubBranford
10.0 out of 10, Exceptional, (2 reviews)
"Had an amazing time with my brothers and mother. Cannot wait to come back and explore the river more. Definitely a great spot for the family"
Kris S.
19. Cypress Landing: Riverfront w/ Private Dock and Beach
Cypress Landing: Riverfront w/ Private Dock and BeachBranford
9.4 out of 10, Exceptional, (3 reviews)
"We LOVED everything about this property!!! It's by far our favorite VRBO!!!! "
Nicole C.
20. Serene, Luxurious Riverside Home w/ Dock!
Serene, Luxurious Riverside Home w/ Dock!Branford
8.8 out of 10, Excellent, (13 reviews)
"We had a great time fishing, kayaking, and swimming in the springs!"
Erin A.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Lafayette County Hotel Reviews
Putnam Lodge Hotel and Spa
8/10 Good
Explore a world of travel with Expedia
- Old Town Hotels
- Hotels near San Felasco Hammock Preserve State Park
- Budget Inn of Jasper
- Hotels near Ichetucknee Springs State Park
- Cabin w/ Fire Pit
- B&B in O Brien
- Cheap Hotels in Old Town
- Hotels near Yogi Bear's Jellystone Park
- Cheap Hotels in Jasper
- American Inn and Suites
- The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee
- The Happy House Tiny Guest House
- Cottages in West Lake
- Holiday Inn Express & Suites Live Oak by IHG
- Hillside Abode
- Newberry Hotels
- Hotels near Manatee Springs State Park
- Hotels near Wes Skiles Peacock Springs State Park
- Keaton Beach Hotels
- Motel 6 Hotels in Lake City
- Horseshoe Beach Hotels
- Regency Inn
- Hotels near Taylor County Sports Complex
- Hotels near O'Leno State Park
- Gulf Breeze Condo #208
- Cabin Rentals in Mayo
- Rv Parks in Lake City
- Motels in Fanning Springs
- Live Oak Hotels
- Wyndham Hotels in Mcalpin
- Mayo Hotels
- Apartments in Jennings
- Villas in Lee
- Cadillac Motel Fanning Springs
- Jasper Hotels
- Cabin Rentals in Jasper
- Kokomo Farms
- Cross City Hotels
- Rv Parks in Jasper
- Spa Hotels in Lake City
- Private 12 acre Ranch sleeps up to 8 on The Santa Fe River.
- Cottages in O Brien
- High Springs Hotels
- Gateway Inn
- Royal Inn Motel
- Quality Inn & Suites Live Oak I
- Lgbt Friendly Hotels in Perry
- Vacation Homes in Athena
- Vv’s Villa Steinhatchee Landing Resort
- Chiefland Hotels
- Guest Houses in Suwannee County
- Skylark Motel
- Perry Hotels
- The Sea Shed
- Steinhatchee Hotels
- Gainesville Hotels
- Holiday Inn Express Hotel & Suites PERRY by IHG
- Madison Hotels
- Greenville Hotels
- Lake City Hotels
- Alachua Hotels
- Motels in Live Oak
- Quality Inn White Springs Suwanee
- Aparthotels in Lake City
- Hilton Hotels in Trenton
- Hotels near Ruth B. Kirby Gilchrist Blue Springs State Park
- Jena Hotels
- Hotels near Spirit of the Suwannee Music Park
- Apartments in Lee
- Deerwood Inn and Madison Campground
- 5 Star Hotels in Trenton
- Athena Hotels
- Trenton Hotels
