Defiance Vacation Packages

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Your Defiance Vacation

Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.

Top Defiance Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
Sep 27 - Oct 1
found 8 hours ago
Roundtrip non-stop flight included
Fort Wayne (FWA) to St. Louis (STL)
8.2/10 Very Good! (754 reviews)
The stay was too short

Reviewed on Jul. 2, 2025

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

3 out of 5
Save 100% on your flight
per person
Sep 27 - Oct 1
found 8 hours ago
Roundtrip non-stop flight included
Fort Wayne (FWA) to St. Louis (STL)
8.8/10 Excellent! (686 reviews)
The food in the restaurant was terrable. I had the meat balls and I could not eat them

Reviewed on Jun. 30, 2025

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

2.5 out of 5
Woodson Terrace
per person
Sep 27 - Oct 1
found 8 hours ago
Roundtrip non-stop flight included
Fort Wayne (FWA) to St. Louis (STL)
8.2/10 Very Good! (32 reviews)
Our comforter had blood stains on top. It was covered by a blanket topper but very much visible.

Reviewed on Jun. 28, 2025

The Cheshire

The Cheshire

4 out of 5
per person
Sep 27 - Oct 1
found 8 hours ago
Roundtrip non-stop flight included
Fort Wayne (FWA) to St. Louis (STL)
8.6/10 Excellent! (1,000 reviews)
Would definitely go back

Reviewed on Jul. 12, 2025

Ballpark Apartments by Barsala

Ballpark Apartments by Barsala

4 out of 5
Downtown St. Louis
Save 100% on your flight
per person
Sep 27 - Oct 1
found 8 hours ago
Roundtrip non-stop flight included
Fort Wayne (FWA) to St. Louis (STL)
7.2/10 Good! (7 reviews)
It's a great location, right across from the Ballpark. It is a fairly spartan apartment set-up, with concrete floors.. a little surprising? Parking is on the street or in a pay lot.

Reviewed on Jun. 8, 2025

Ready to book your vacation to Defiance?

 

Choose your dates

Defiance Hotel Deals

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is CA $129 per night from Aug 3 to Aug 4
CA $129
CA $149 total
Aug 3 - Aug 4
includes taxes & fees
8.4/10 Very Good! (1,023 reviews)
"Everything was great, clean and comfortable, the only problem was, breakfast was suppose to be available at 6am, at 7 there was still no breakfast, front desk said they didn't know why"

Reviewed on Jul. 10, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $151 per night from Jul 15 to Jul 16
CA $151
CA $196 total
Jul 15 - Jul 16
includes taxes & fees
8.2/10 Very Good! (1,967 reviews)
"Check in and my stay were excellent. I was warmly welcomed and was able to settle in for two comfortable nights."

Reviewed on Jul. 11, 2025

Hollywood Casino & Hotel St. Louis
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
2.5 out of 5
1970 Craig Rd, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $88 per night from Aug 10 to Aug 11
CA $88
CA $103 total
Aug 10 - Aug 11
includes taxes & fees
4.6/10 (1,012 reviews)
"Lots of dinning options close."

Reviewed on Jun. 21, 2025

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
See all 828 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Discover the most popular places to visit in Defiance

Busch Stadium

Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Gateway Arch featuring modern architecture, a city and a skyscraper

Gateway Arch

4.5/5(37 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

4.5/5(7 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

What to do in Defiance

St Louis: City Museum General Admission Ticket

St Louis: City Museum General Admission Ticket

CA $30
per adult
96% of travellers recommend
St Louis: City Museum General Admission Ticket
St. Louis Arch Walking Tour and Entrance Ticket

St. Louis Arch Walking Tour and Entrance Ticket

CA $68
per adult
St. Louis Arch Walking Tour and Entrance Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

CA $44
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
See all activities in Defiance

Frequently asked questions

How much does a Defiance vacation package cost?
You can grab a vacation package to this destination from CA $509 on Expedia. However, how much your vacation to Defiance costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Defiance?
The off-season is the best time to travel to Defiance if you're hoping to keep costs down. Another tip for getting cheap Defiance vacation packages? Avoid visiting during public holidays and any major festivals.
How many days is enough for Defiance?
The ideal duration for your Defiance vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to go to all the major attractions and discover some hidden spots along the way.
How to find the best Defiance package deals?
Begin your search for a Defiance package deal by entering your travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Defiance package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Defiance getaway off to a flying start.
Is it cheaper to book a Defiance vacation as a package?
You can enjoy significant savings on your next Defiance retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Defiance?
If you've got your Defiance vacation dates locked in, book as early as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are great for travelling on a whim.
How to plan a trip to Defiance?

  1. Choose your dates: The things you'd like to do in Defiance and your favourite season can help you decide when to get away.
  2. Set a budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Defiance. Then, pick a property that works with your budget, whether that's a low-cost stay or a lavish retreat.
  3. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Defiance. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Defiance vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.