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Cherokee Vacation Rentals

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Our top choices for Cherokee vacation rentals

1. The 72 Rendezvous

The 72 Rendezvous
Cherokee
The price is CA $203
CA $428 total
includes taxes & fees
Sep 27 - Sep 28
The 72 Rendezvous

2. Perfect lake front cottage! Now with stairs to the water!

Perfect lake front cottage! Now with stairs to the water!
Waterloo
9.8 out of 10, Exceptional, (130 reviews)
"Wonderful stay! Great views at a cozy cabin!"
United States
Andrew A.
The price is CA $278
CA $507 total
includes taxes & fees
Oct 3 - Oct 4
Perfect lake front cottage! Now with stairs to the water!

3. Iuka Historic Downtown King Loft C

Iuka Historic Downtown King Loft C
Iuka
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful place to stay"
United States
Sherry B.
The price is CA $161
CA $323 total
includes taxes & fees
Sep 27 - Sep 28
Iuka Historic Downtown King Loft C

4. Fern Hollow Treehouse, rustic escape cozy romantic

Fern Hollow Treehouse, rustic escape cozy romantic
Tishomingo
9.8 out of 10, Exceptional, (42 reviews)
"Beautiful and unique place to stay! The outdoor bathhouse was a great way to cool off from the humidity! Bring your mosquito repellent!!"
United States
Mel L.
The price is CA $246
CA $383 total
includes taxes & fees
Sep 24 - Sep 25
Fern Hollow Treehouse, rustic escape cozy romantic

5. 3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital
Muscle Shoals
9.6 out of 10, Exceptional, (74 reviews)
"We had a wonderful time at this lovely home. The pool was amazing."
United States
Tim c.
The price is CA $168
CA $475 total
includes taxes & fees
Sep 29 - Sep 30
3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

6. The Gypsy Queen

The Gypsy Queen
Tishomingo
9.6 out of 10, Exceptional, (4 reviews)
"Cute funky fun little cottage. We loved it"
United States
Ashley P.
The price is CA $175
CA $305 total
includes taxes & fees
Sep 25 - Sep 26
The Gypsy Queen

7. Lagniappe in Florence

Lagniappe in Florence
Florence
10.0 out of 10, Exceptional, (51 reviews)
"A wonderful spot for a weekend getaway! Loved staying here!"
United States
addie s.
The price is CA $215
CA $447 total
includes taxes & fees
Sep 24 - Sep 25
Lagniappe in Florence

8. Loft in the Heart of Downtown — steps away from Pickett, UNA, Dining, Shops

Loft in the Heart of Downtown — steps away from Pickett, UNA, Dining, Shops
Florence
10.0 out of 10, Exceptional, (33 reviews)
"We love staying at here. Great location and communication with the owners."
United States
jonathan h.
The price is CA $233
CA $449 total
includes taxes & fees
Sep 27 - Sep 28
Loft in the Heart of Downtown — steps away from Pickett, UNA, Dining, Shops

9. Country Bliss

Country Bliss
Tishomingo
10.0 out of 10, Exceptional, (26 reviews)
"Love this place"
United States
Randall S.
The price is CA $125
CA $239 total
includes taxes & fees
Sep 26 - Sep 27
Country Bliss

10. "Cottage @ JP Coleman"-perfect getaway at Pickwick

"Cottage @ JP Coleman"-perfect getaway at Pickwick
Iuka
9.6 out of 10, Exceptional, (47 reviews)
"Clean, decorated well, with well stocked items for hygiene, if you forgot something, nice size and excellent communication. Highly recommend. "
United States
Charles B.
The price is CA $168
CA $353 total
includes taxes & fees
Sep 27 - Sep 28
"Cottage @ JP Coleman"-perfect getaway at Pickwick

11. Summer Openings! Perfect spot on lake for fishing! Spacious home & backyard

Summer Openings! Perfect spot on lake for fishing! Spacious home & backyard
Iuka
9.8 out of 10, Exceptional, (59 reviews)
"Second time staying at this house. Great house, great location, great hosts. "
United States
Robert W.
The price is CA $171
CA $376 total
includes taxes & fees
Sep 24 - Sep 25
Summer Openings! Perfect spot on lake for fishing! Spacious home & backyard

12. Romantic Cozy Cottage 0.8 miles from JP Coleman State Park / Pickwick / Iuka

Romantic Cozy Cottage 0.8 miles from JP Coleman State Park / Pickwick / Iuka
Iuka
10.0 out of 10, Exceptional, (2 reviews)
"Super cute tiny home and really close to JP Coleman boat ramp. I would stay again and again!"
United States
EMILY B.
The price is CA $161
CA $264 total
includes taxes & fees
Sep 24 - Sep 25
Romantic Cozy Cottage 0.8 miles from JP Coleman State Park / Pickwick / Iuka

13. Stenson Hollow Lake Condo

Stenson Hollow Lake Condo
Muscle Shoals
9.6 out of 10, Exceptional, (113 reviews)
"The view of the lake was nice and we enjoyed seeing the fireflies at night"
United States
Wayne
The price is CA $133
CA $291 total
includes taxes & fees
Sep 24 - Sep 25
Stenson Hollow Lake Condo

14. The Loft on Main

The Loft on Main
Belmont
9.8 out of 10, Exceptional, (19 reviews)
"Can't say enough good things about this place.... LOVED IT!!"
United States
Mark
The price is CA $139
CA $254 total
includes taxes & fees
Sep 29 - Sep 30
The Loft on Main

15. Murphy House at Pickwick

Murphy House at Pickwick
Tishomingo County
10.0 out of 10, Exceptional, (1 review)
The price is CA $351
CA $549 total
includes taxes & fees
Sep 24 - Sep 25
Murphy House at Pickwick

16. Crossroads to Pickwick Cabin SMOOTH SAILING

Crossroads to Pickwick Cabin SMOOTH SAILING
Iuka
9.8 out of 10, Exceptional, (27 reviews)
"The property was very clean and located perfectly between JP Coleman State Park and Sportmans at the TN Line. Great spot will stay there again."
United States
John B.
The price is CA $223
CA $336 total
includes taxes & fees
Oct 17 - Oct 18
Crossroads to Pickwick Cabin SMOOTH SAILING

17. Boat Parking & Shore Power, Dog-Friendly Duplex, Fenced Yard Near Pickwick Lake

Boat Parking & Shore Power, Dog-Friendly Duplex, Fenced Yard Near Pickwick Lake
Sheffield
9.4 out of 10, Exceptional, (8 reviews)
"Nice clean property. Conveniently located within 2-20 mins of shopping and restaurants."
United States
Kristy
The price is CA $87
CA $243 total
includes taxes & fees
Sep 27 - Sep 28
Boat Parking & Shore Power, Dog-Friendly Duplex, Fenced Yard Near Pickwick Lake

18. Emerald Hour Loft: 2 mins from UNA

Emerald Hour Loft: 2 mins from UNA
Florence
9.6 out of 10, Exceptional, (5 reviews)
"Perfect location and great Accommodations. Host was easy to contact and plan to stay again if available. ."
United States
Andrea
The price is CA $161
CA $323 total
includes taxes & fees
Sep 27 - Sep 28
Emerald Hour Loft: 2 mins from UNA

19. NO PETS/NON SMOKING 3-bedroom home in Counce with WiFi, AC

NO PETS/NON SMOKING 3-bedroom home in Counce with WiFi, AC
Counce
9.6 out of 10, Exceptional, (8 reviews)
"Loved our stay. Was a great place to host friends before going out on the lake and then was a great place to sleep. Plenty of space for the 4 of us with even an extra bedroom! Amenities listed were as described and the house was clean and cozy. Perfect for a lake weekend"
United States
Hunter H.
The price is CA $210
CA $449 total
includes taxes & fees
Oct 4 - Oct 5
NO PETS/NON SMOKING 3-bedroom home in Counce with WiFi, AC

20. BRAND NEW !! Cozy 1-bedroom cabin near PICKWICK LAKE with room for boat parking

BRAND NEW !! Cozy 1-bedroom cabin near PICKWICK LAKE with room for boat parking
Iuka
The price is CA $191
CA $234 total
includes taxes & fees
Oct 1 - Oct 2
BRAND NEW !! Cozy 1-bedroom cabin near PICKWICK LAKE with room for boat parking
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cherokee Hotel Reviews

Find out more about Cherokee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Cherokee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Cherokee?

Yes, you can find vacation rentals near popular points of interest in Cherokee, or you can select a secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals in Cherokee?

Rustic Cabin overlooking Pickwick Lake: This Cherokee vacation home rental is located on a lake and offers a barbecue grill, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Our travelers also rate RIVERTON LAKESIDE COTTAGE ON PICKWICK LAKE as a favorite home for rent in Cherokee.

How many vacation rentals are there in Cherokee?

Choose from 7 Expedia vacation rentals in Cherokee for a memorable vacation.

What can I see and do in Cherokee?

Pickwick Lake and Tennessee River are a couple of lovely local spots to get outside and enjoy nature. Cane Creek Canyon Nature Preserve and Ivy Green are a couple of places you'll find in the larger area.

What are vacation rentals like in Cherokee?

Vacation rentals are privately owned accommodations you can reserve for several days or longer in Cherokee. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for family trips.