Title: Book the Best Big Pine Key SPA Resorts from CA $280 - Spa Hotels in Big Pine Key, FL | Expedia.ca [Big Pine Key Travel Guide](https://expedia.ca/Big-Pine-Key.dx7195)[Hotels in Big Pine Key](https://expedia.ca/Big-Pine-Key-Hotels.d7195.Travel-Guide-Hotels)[Vacation Rentals in Big Pine Key](https://expedia.ca/Big-Pine-Key-Vacation-Rentals.d7195.Travel-Guide-VacationRentals)[Flights to Big Pine Key](https://expedia.ca/Cheap-Flights-To-Big-Pine-Key.d7195.Travel-Guide-Flights)[Things to do in Big Pine Key](https://expedia.ca/Things-To-Do-In-Big-Pine-Key.d7195.Travel-Guide-Activities)[Big Pine Key Car Rentals](https://expedia.ca/Car-Rentals-In-Big-Pine-Key.d7195.Car-Rental-Guide)[Big Pine Key Vacation Packages](https://expedia.ca/Big-Pine-Key.d7195.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/497000/497701-big-pine-key.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Big Pine Key, FL from CA $280 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Big Pine Key Spa Hotels Tonight [Oct 3 - Oct 4](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2025-10-03&endDate=2025-10-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 4 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2025-10-04&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2025-10-10&endDate=2025-10-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Big Pine Key Spa Hotels ![Steam room, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/aa92b0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/acafccbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/962eab99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/fe602972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Faro Blanco Resort Marathon 9.0/10 Wonderful (1000) "Room was clean. Staff was very friendly. Great ocean view. Excellent value." CA $200 CA $280 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) ![Body treatments, aromatherapy, deep-tissue massages, Swedish massages](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/3ac23f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/2097bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 2 Bedrooms, Beachfront | Living area](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/8c99c2b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/a50ca43c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquility Bay Beachfront Hotel and Resort Marathon 8.8/10 Excellent (1001) "Amazing stay, our second time here and we love it, never fails when you need a relaxing and quiet get away! " CA $313 CA $442 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/00c7105d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/e1765627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/1b2ea44f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/d5633e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isla Bella Beach Resort & Spa Marathon 9.2/10 Wonderful (1051) "Absolutely beautiful resort!" CA $325 CA $449 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-17&endDate=2025-10-18®ionId=7195&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Big Pine Key ### Top Big Pine Key attractions for a relaxing vacation Big Pine Key, known for its lush natural beauty and serene atmosphere, offers a perfect blend of relaxation and adventure for travellers seeking spa hotel experiences. Begin your journey at the National Key Deer Refuge, where you can spot the charming Key deer and enjoy tranquil nature walks, immersing yourself in the untouched Florida Keys ecosystem. After a day of exploration, unwind at the beaches of Bahia Honda State Park, renowned for its stunning sunsets and soft sandy shores, ideal for a peaceful evening stroll. For those wanting to delve into the local culture, the Big Pine Key Flea Market showcases unique crafts and local delicacies, providing a delightful shopping experience. If you're feeling adventurous, consider a kayaking excursion through the nearby mangroves, where you can discover diverse wildlife while enjoying the gentle sounds of nature. To enhance your stay, the area boasts several charming hotels with spa services nestled amidst tropical gardens, offering treatments that incorporate local ingredients, ensuring you leave feeling rejuvenated and pampered. With attentive guest service and a focus on quality, your experience in Big Pine Key will be both memorable and restorative. ## Top Big Pine Key Hotel Reviews ![Tranquility Bay Beachfront Hotel and Resort](//images.trvl-media.com/lodging/1000000/120000/117100/117099/a50ca43c_y.jpg) ### Tranquility Bay Beachfront Hotel and Resort 10/10 Excellent "Me encantó en todos los sentidos. Volvería con toda seguridad." [](https://expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![Courtyard by Marriott Faro Blanco Resort](//images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/962eab99_y.jpg) ### Courtyard by Marriott Faro Blanco Resort 10/10 Excellent "Room was clean. Staff was very friendly. Great ocean view. Excellent value." [](https://expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) ![Banana Bay Resort & Marina](//images.trvl-media.com/lodging/1000000/930000/921900/921804/5c7bc79a_y.jpg) ### Banana Bay Resort & Marina 10/10 Excellent "good" [](https://expedia.ca/Marathon-Hotels-Banana-Bay-Resort-Marina.h921804.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Big Pine Key? > Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the beaches in Big Pine Key - worth a picture or two! Be sure to enjoy activities like kayaking and snorkeling during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation. ### What's there to see and do in Big Pine Key? > Enjoy all that Big Pine Key has to offer and visit Calusa Beach, Bahia Honda State Park, and Big Pine Key Flea Market. If you have extra time while you're in the area, you might want to see Coupon Bight Aquatic Preserve and Cook Island. ### What is a Big Pine Key spa hotel? > Spa hotels in Big Pine Key provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. 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[Hotels & Resorts for Couples in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Couples-Resorts-Hotels.0-n553248635976481798-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Family-Hotel.0-n553248635976481798-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Golf Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Golf-Hotel.0-n553248635976481798-0-tGolfHotel.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts and in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Honeymoon-Hotels.0-n553248635976481798-0-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Hotels with Early Check-in in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Hotel-With-Early-Check-In.0-n553248635976481798-0-thotelwithearlycheckin.Travel-Guide-Filter-Hotels) - [Hotels with a Lazy River in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Hotels-With-A-Lazy-River.0-n553248635976481798-0-tHotelswithaLazyRiver.Travel-Guide-Filter-Hotels) - [Hotels with Balconies in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Hotels-With-Balconies.0-n553248635976481798-0-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Hotels-With-Smoking-Rooms.0-n553248635976481798-0-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Hotels-With-Tennis-Courts.0-n553248635976481798-0-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Luxury-Hotel.0-n553248635976481798-0-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Mountain-Hotels.0-n553248635976481798-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Oceanfront-Hotels.0-n553248635976481798-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Pet-Friendly-Hotel.0-n553248635976481798-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Romantic-Hotel.0-n553248635976481798-0-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Shopping Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Shopping-Hotel.0-n553248635976481798-0-tShoppingHotel.Travel-Guide-Filter-Hotels) - [Ski Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Ski-Hotel.0-n553248635976481798-0-tSkiHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Spa-Hotel.0-n553248635976481798-0-tSpaHotel.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Wedding-Hotels.0-n553248635976481798-0-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Winery Hotels in Sunset Key](https://www.expedia.ca/Sunset-Key-Key-West-Hotels-Winery-Hotel.0-n553248635976481798-0-tWineryHotel.Travel-Guide-Filter-Hotels) - [Adults Only Resorts & in Whispering Pines](https://www.expedia.ca/Whispering-Pines-Big-Pine-Key-Hotels-Adults-Only-Resorts.0-n553248635976471032-0-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Golf Hotels in Whispering Pines](https://www.expedia.ca/Whispering-Pines-Big-Pine-Key-Hotels-Golf-Hotel.0-n553248635976471032-0-tGolfHotel.Travel-Guide-Filter-Hotels) - [Mountain Hotels in Whispering Pines](https://www.expedia.ca/Whispering-Pines-Big-Pine-Key-Hotels-Mountain-Hotels.0-n553248635976471032-0-tMountainHotels.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Whispering Pines](https://www.expedia.ca/Whispering-Pines-Big-Pine-Key-Hotels-Pet-Friendly-Hotel.0-n553248635976471032-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Whispering Pines](https://www.expedia.ca/Whispering-Pines-Big-Pine-Key-Hotels-Waterpark-Hotels.0-n553248635976471032-0-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Book Spa Hotels in Big Pine Key on Expedia.com](https://www.expedia.com/Big-Pine-Key-Hotels-Spa-Hotel.0-0-d7195-tSpaHotel.Travel-Guide-Filter-Hotels)