Antioquia Vacation Packages

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  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Your Antioquia Vacation

Leave all the planning up to us with an Antioquia vacation package. With everything arranged before you jet off, the only thing you'll need to do is relax and experience this destination's culture and charm. With so many things to explore on a trip to Antioquia, it can be tricky to know where to begin. Kick off your travels in Medellin at Santafé Mall and Lleras Park — two much-loved attractions here. Another city worth adding to your itinerary is Guatapé. Be sure not to miss Peñol-Guatapé Reservoir and Parque Comfama. From the instant you book your Antioquia vacation to when you return home, Expedia has your back each step of the way.

Top vacation destinations in Antioquia

Top Antioquia Vacation Deals

Price found within the past 48 hours. Click for updated prices.
La Martina Campestre
Devú
Novotel Medellín El Tesoro
Autenthico Sajonia Hotel Aeropuerto
Binn Hotel

Where to stay in Antioquia

Find the best Antioquia areas and neighborhoods for the activities you enjoy most. Learn more about Antioquia

Antioquia Hotel Deals

Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
# 37-40 Calle 9A Medellín
The price is CA $90 per night from May 11 to May 12
CA $90
CA $90 total
May 11 - May 12
Calle Flora Hotel by Jalo
The Click Clack Hotel Medellin

The Click Clack Hotel Medellin

5 out of 5
Calle 10B # 37-29 Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is CA $276 per night from May 25 to May 26
CA $276
CA $276 total
May 25 - May 26
9.2/10 Wonderful! (1,132 reviews)
Hotel diferente buena ubicacion buen desayuno y servicios si volveria

Reviewed on May 9, 2026

The Click Clack Hotel Medellin
Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

4 out of 5
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
The price is CA $93 per night from Jun 9 to Jun 10
CA $93
CA $93 total
Jun 9 - Jun 10
9.2/10 Wonderful! (1,956 reviews)
Nos encantó todo, el staff es increíble.

Reviewed on May 10, 2026

Hashtag 98 Hotel By Jalo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Antioquia vacation package cost?
Choose from any combination of hotels, flights and car rentals, and you can be vacationing in Antioquia from just CA $885. And the more you bundle, the more money you save. The vacation of your dreams has never been more affordable.
How do I get a cheap travel package to Antioquia?
Creating your own Antioquia vacation package with Expedia is a smart way to save. We offer more than 550 air carriers and 1,000,000 hotels around the globe. With such an amazing range to choose from, you'll have no difficulty putting together your dream getaway.
Where should I stay in Antioquia?
If you're planning to check out fantastic sights such as Atanasio Giradot Stadium and Botero Plaza, head straight for Medellin. You might want to stay for a while to really experience this vibrant city.
What are the top hotels in Antioquia?
Look up Viaggio Medellín Grand Select and Novotel Medellín El Tesoro. They're the first choice for lots of travelers to Medellin. If Envigado is next stop on your itinerary, The Click Clack Hotel Medellin and NH Collection Medellín Royal are a couple of great options.
How far in advance should I book my Antioquia vacation?
Earlier is always better. Airlines usually advertise flight tickets up to a year ahead of departure, and this is a perfect opportunity to pick up some of the lowest prices. Just been told you need to take all your vacation days next month? Don't fret. Expedia are never short of fantastic deals to send you off on the getaway of your dreams, at a price you can afford.
What does an Expedia Antioquia travel package include?
Expedia has everything you need to plan your Antioquia trip, but what goes into your package is up to you. Select from a combination of flights, hotels and rental cars. Looking for some tours or activities to fill in your time? Once you've made your booking, you can add them too. No matter your style or budget, there's a package to match your needs.
What should I know before booking an Antioquia travel package?
When you book your flights, hotels and car rentals together, you'll pick up awesome discounts. Whether you're organizing a beach break in a villa or would rather stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with an Antioquia Expedia vacation package?
With a vacation package, the choice is in your hands. Whether you'd prefer to fly to Antioquia in business or coach, simply select from the available airline options. Expedia has access to over 550 airline partners around the world.
If I'm not able to travel, can I cancel my Antioquia vacation package?
You can. We get that even the best-laid plans can go awry, so we're happy to help if you need to make changes to your Antioquia vacation package. You may be able to amend or cancel your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Look up our Customer Service Portal for more information. Also, check your itinerary for the finer details on change fees.

Discover the most popular places to visit in Antioquia

What to do in Antioquia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.