A coastal town with colorful buildings, a prominent church with a blue dome, and a clear blue sea.

Best 5 Star Hotels in Syros CA $146

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Check availability on Syros 5 Star Hotels

Tonight
Oct 25 - Oct 26
Tomorrow
Oct 26 - Oct 27
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Syros 5-star hotels

A modern outdoor lounge area with a pool, seating, and a view of the sea.
A modern outdoor staircase with integrated lighting, surrounded by potted plants and large vases.
A modern room with a large window overlooking a body of water and a yacht. There is a sofa, a small round table, and a chair.
A modern hotel room with a large bed, a desk, and a view of the ocean.

1. Myconian Deos - The Set

Myconian Deos - The Set
Mykonos
United States
Gisela
Myconian Deos - The Set
An infinity pool with clear blue water, a white infinity pool edge, and a view of the sea with boats.
A modern hotel room with a large bed, a sofa, two round wooden tables, a TV, and a view of the sea and buildings.
A person lounging on a cushioned outdoor seating area with a view of the sea and a distant rocky island.
A pathway leading to a rocky beach area with white pebbles and agave plants, overlooking the sea.

2. Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux
Mykonos
United States
Scott
CA $276
CA $337 total
includes taxes & fees
Oct 25 - Oct 26
Myconian Ambassador Hotel Relais & Chateaux
A poolside area with lounge chairs and a view of the sea at night.
A modern, white-themed living room with a dining area, large windows offering a view of the sea, and a minimalist design.
A modern bathroom with a large bathtub, wooden flooring, and a view of a cruise ship.
A modern living room with a large rock feature, a white sofa, and a view of the sea.

3. CAVO TAGOO MYKONOS

CAVO TAGOO MYKONOS
Mykonos
United Arab Emirates
Balqees
CAVO TAGOO MYKONOS
An infinity pool with lounge chairs and a sunset view.
A round table with a vase and two glasses, overlooking a body of water and distant land.
A corridor with a view of the sea and a distant mountain.
A modern hotel room with a large bed, a flat-screen TV, a ceiling light, and a view of the outdoors.

4. Myconian Korali Relais & Chateaux

Myconian Korali Relais & Chateaux
Mykonos
United States
Eric
CA $283
CA $346 total
includes taxes & fees
Oct 25 - Oct 26
Myconian Korali Relais & Chateaux
A modern outdoor pool area with lounge chairs and a fire feature.
A spacious living room with a sectional sofa, two armchairs, a glass coffee table, and large windows with white shutters.
A restaurant setting with tables set for dining, featuring candlelight and hanging lamps.
An outdoor patio with a modern design, featuring a glass ceiling, seating areas, and a dining setup.

5. Semeli Hotel

Semeli Hotel
Mykonos
United States
Veronica
CA $211
CA $264 total
includes taxes & fees
Oct 27 - Oct 28
Semeli Hotel
A swimming pool with star-shaped lights at night.
A bedroom with a bed, a hanging lamp, a view of a pool, and a seating area with cushions and a bowl of fruit.
A marina with multiple yachts docked, rocky coastline, and buildings on the right.
A modern interior with a wooden partition, a chandelier, and a seating area with two white poufs.

6. Palladium Hotel

Palladium Hotel
Mykonos
United States
Maria
Palladium Hotel
An outdoor pool area with a view of the sea, a wooden table with chairs, and a seating area with a sofa and cushions.
A modern bedroom with a wooden floor, white bed, and a large mirror.
A white building with a pool, outdoor seating, and a stone wall.
An arched pathway leading to a balcony with a view of the sea, a sofa, and potted plants.

7. Belvedere Hotel - The Leading Hotels of the World

Belvedere Hotel - The Leading Hotels of the World
Mykonos
United States
Rhonda
CA $402
CA $481 total
includes taxes & fees
Oct 28 - Oct 29
Belvedere Hotel - The Leading Hotels of the World
A pool area with a view of the sea, stone walls, and a hanging chair.
A coastal beach with clear turquoise waters, a sandy shore, and several boats.
A multi-story hotel with stone architecture, a pool area with lounge chairs, and a view of rocky terrain.
A rooftop terrace with a wooden pergola, stone walls, a cushioned seating area, and a view of the ocean.

8. Tropicana Suites & Villas

Tropicana Suites & Villas
Mykonos
United States
Fenold
Tropicana Suites & Villas
A pool with a view of the sea and mountains, a yacht in the distance, and a cactus garden.
A view from a window of a room with a wooden ceiling, a stone wall, and a poolside area with a table and chairs.
A beach with lounge chairs and umbrellas, a woman in a swimsuit walking, and clear blue water.
A modern interior with a large window offering a coastal view, a wooden table, a cushioned chair, and a fireplace.

9. Bill&Coo Mykonos

Bill&Coo Mykonos
Mykonos
United States
Dean
Bill&Coo Mykonos
A swimming pool with a clear view of the water, a white poolside area, and two empty glasses on a white surface.
A modern building with a stone facade and a clear sky.
A waterfront resort with outdoor seating, a pool, and boats in the background.
A spacious bedroom with a large bed, a bathroom with a large mirror, and a view of the sea.

10. Nissaki Boutique Hotel

Nissaki Boutique Hotel
Mykonos
United States
Arisel
CA $636
CA $748 total
includes taxes & fees
Oct 25 - Oct 26
Nissaki Boutique Hotel
A resort with multiple swimming pools, a beach area with umbrellas, and boats in the water.
A sunlit outdoor seating area with white furniture, a wooden coffee table, and a view of the sea with yachts.
View from property
A pool with a curved edge, a white building with arches, and a view of the sea with a sailboat.

11. Mykonos Blu, A Resort to Live

Mykonos Blu, A Resort to Live
Mykonos
United States
Hagop
Mykonos Blu, A Resort to Live
A calm body of water reflecting the sky during sunset.
A modern bar area with a view of the water, wooden furniture, and unique light fixtures.
A beach with sun loungers and umbrellas, a stone railing, and a view of the sea and distant hills.
A bedroom with a large window overlooking a coastal landscape, a bed, a chair, and a small table with a vase.

12. Amazon Mykonos Resort & Spa

Amazon Mykonos Resort & Spa
Mykonos
Canada
Eldina
Amazon Mykonos Resort & Spa
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a white building.
A spa area with a wooden bench, a person attending to another on the bench, and a white canopy structure.
A modern bedroom with a bed, pillows, a bedside table, and a hanging light fixture.
A modern interior with a white bench, wooden beams, a large mirror, and a wicker basket.

13. Axel Beach Mykonos - Adults Only

Axel Beach Mykonos - Adults Only
Mykonos
United States
Eduardo
CA $131
CA $173 total
includes taxes & fees
Oct 25 - Oct 26
Axel Beach Mykonos - Adults Only
A pool area with stone walls and palm trees, leading to a view of the sea.
A restaurant with multiple tables and chairs, large windows offering a view of a cityscape and water at night.
A modern bathroom with a large window, a bathtub, a towel, and a tray with food items.
A modern outdoor space with a stone wall, a black bathtub, and a seating area with a plant.

14. Aeonic Suites and Spa

Aeonic Suites and Spa
Mykonos
Canada
Daryous
Aeonic Suites and Spa
A poolside view with a clear blue sea and a mountain in the distance.
A restaurant with tables and chairs arranged to face a large window overlooking a beach and ocean.
A coastal landscape with clear turquoise waters, rocky shoreline, and a sandy beach.
A spacious lobby with a polished marble floor, elegant sofas, and a grand chandelier.

15. Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa
Mykonos
United States
Ian
Saint John Hotel Villas & Spa
A modern pool area with lounge chairs and umbrellas, a glass-enclosed bar, and a clear view of the sky.
A modern, spacious room with a white sofa set, wicker chairs, and large windows offering a view of the sea.
A modern hotel room with a large bed, a sofa, a desk, and a view of the sea.
A bar area with a stone wall backdrop, bar stools, and a large planter with a tree.

16. Myconian Kyma, a Member of Design Hotels

Myconian Kyma, a Member of Design Hotels
Mykonos
United Kingdom
Anahita
Myconian Kyma, a Member of Design Hotels
A modern outdoor lounge area with a pool, wooden pergola, and hanging chairs.
A living room with two sofas, a coffee table, and a fireplace.
A resort with a poolside area, sun loungers, umbrellas, and a hillside view of white buildings.
A beachside restaurant with wicker furniture, stone pillars, and umbrellas overlooking the sea.

17. Santa Marina, a Luxury Collection Resort, Mykonos

Santa Marina, a Luxury Collection Resort, Mykonos
Mykonos
United Kingdom
FLORENCE
Santa Marina, a Luxury Collection Resort, Mykonos
A luxurious outdoor dining area with wicker chandeliers, palm trees, and a pool overlooking a marina.
A bedroom with a large bed, a mirror, and a view of an outdoor area with plants and a chair.
An aerial view of a beachside hotel with rows of sun loungers and palm trees.
A seaside restaurant with wicker furniture, tables set with glasses and plates, and umbrellas providing shade.

18. O by Myconian, Mykonos, a Member of Design Hotels

O by Myconian, Mykonos, a Member of Design Hotels
Mykonos
United States
Sahar
O by Myconian, Mykonos, a Member of Design Hotels
A luxurious outdoor hot tub area with a sunset view, stone pillars, and lounge chairs.
A modern room with a wooden floor, a bed with a tray of breakfast items, a white sofa, and a view of a coastal landscape through a glass door.
A woman sitting at a table with a book, a candle, and a drink. The room has a large window with a view of a bridge and mountains.
A woman in a blue dress standing in a stone-walled room with a view of the sunset over the sea.

19. Tharroe of Mykonos

Tharroe of Mykonos
Mykonos
United States
Alexis
Tharroe of Mykonos
A beach with rows of sun loungers and umbrellas, a clear blue sea, and several sailboats in the background.
A man standing in a doorway with a view of a pool and ocean.
A modern bedroom with a large bed, a bedside table with a plant, and a view of the sea through a balcony.
A woman dining at an outdoor table with a view of a beach resort, including lounge chairs and umbrellas.

20. Mykonos Ammos Hotel

Mykonos Ammos Hotel
Mykonos
United Kingdom
Kelly
Mykonos Ammos Hotel
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syros.
Poseidon Hotel & Suites

Poseidon Hotel & Suites

Mykonos Town Mykonos Mykonos Island
CA $234
CA $282 total
Oct 25 - Oct 26
includes taxes & fees
Poseidon Hotel & Suites
Mykonos Adonis Hotel

Mykonos Adonis Hotel

Chora Mykonos Mykonos Island
CA $153
CA $178 total
Nov 2 - Nov 3
includes taxes & fees
9.4/10 Exceptional! (643 reviews)
Mykonos Adonis Hotel
Harmony Boutique Hotel

Harmony Boutique Hotel

Mykonos Town Mykonos Mykonos Island
CA $124
CA $146 total
Nov 1 - Nov 2
includes taxes & fees
9.4/10 Exceptional! (533 reviews)
Harmony Boutique Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syros

Wander through Ermoupoli's neoclassical buildings and marble squares before catching a performance at the historic Apollo Theatre. Swim at Galissas beach, then climb the hill to Ano Syros where medieval streets offer spectacular views across the Aegean.

See all hotels in Syros
A cobblestone street lined with colorful buildings, a prominent yellow church with a blue dome, and a clear blue sky.

Top Syros Hotel Reviews

Myconian Deos - The Set

Myconian Deos - The Set

10/10 Excellent
"We stayed here for our honeymoon in Mykonos and it's been wonderful in every aspect. Highly recommend."
Yi 5-night trip
Posted 4 hours ago
Myconian Deos - The Set
Myconian Ambassador Hotel Relais & Chateaux

Myconian Ambassador Hotel Relais & Chateaux

10/10 Excellent
"Beautiful hotel. Loved the pool"
Nadine 4-night trip
Posted 5 days ago
Myconian Ambassador Hotel Relais & Chateaux
Saint John Hotel Villas & Spa

Saint John Hotel Villas & Spa

10/10 Excellent
"Great place, would definitely come back. the staff was great and the beach and rooms were exactly what we wanted for our trip"
Ian 3-night trip
Posted 6 days ago
Saint John Hotel Villas & Spa

Find out more about Syros

Five Star Hotels in Syros

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Syros so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Syros and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Syros

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Syros

The results are in, and Syros 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Syros! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Syros today and settle down in the lap of luxury tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Syros?
How much you pay for a 5-star hotel in Syros can vary depending on when you prefer to travel and how long you plan to be away, among other factors. Take advantage of our price per night filter and other search tools to score the best rate on a high-end stay.
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What makes a hotel 5 stars in Syros?
In Syros, a hotel must offer a certain amount of high-end amenities to be designated 5 stars. These may include on-site gyms, spas and saunas, gourmet restaurants, premium bedding, luxury toiletries and more. What also sets 5-star hotels apart is their superior service. You'll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may also offer thoughtful touches such as welcome gifts.
Are there any 5-star all-inclusive resorts in Syros?
Our filter tool is the best way to find exactly what you're looking for. Check the "All inclusive" and "5-star" boxes to show the finest resorts in Syros where your accommodations, meals, entertainment and activities are included in the upfront price. At these retreats, your vacation is absolute indulgence from the moment you pull up to the entrance.

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