Title: 5 Stars Hotels in Guadalupe, California from CA $234 - Find Cheap Guadalupe Hotels With 5 Stars | Expedia.ca [Guadalupe Travel Guide](https://expedia.ca/Guadalupe.dx6204275)[Hotels in Guadalupe](https://expedia.ca/Guadalupe-Hotels.d6204275.Travel-Guide-Hotels)[Vacation Rentals in Guadalupe](https://expedia.ca/Guadalupe-Vacation-Rentals.d6204275.Travel-Guide-VacationRentals)[Flights to Guadalupe](https://expedia.ca/Cheap-Flights-To-Guadalupe.d6204275.Travel-Guide-Flights)[Guadalupe Car Rentals](https://expedia.ca/Car-Rentals-In-Guadalupe.d6204275.Car-Rental-Guide)[Guadalupe Vacation Packages](https://expedia.ca/Guadalupe.d6204275.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Guadalupe 5 Star Hotels Tonight [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-01-16&endDate=2026-01-17&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-01-17&endDate=2026-01-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6204275&startDate=2026-01-23&endDate=2026-01-25&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Guadalupe 5-star hotels ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/c2079151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/2344a3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/caf8168a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/8e543ea2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Stone Inn [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) Santa Maria 9.8/10 Exceptional (605 reviews) "Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shannon CA $218 CA $260 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Guadalupe-Hotels.s50-0-d6204275.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Guadalupe-Hotels.s50-0-d6204275.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Guadalupe. ![Inn at the Pier Pismo Beach, Curio Collection by Hilton](https://images.trvl-media.com/lodging/19000000/18680000/18676000/18675941/w3838h2559x2y0-97fcea63_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Inn at the Pier Pismo Beach, Curio Collection by Hilton 601 Cypress Street Pismo Beach CA CA $204 CA $234 total Jan 26 - Jan 27 includes taxes & fees 8.4/10 Very Good! (1,001 reviews) [](https://expedia.ca/San-Luis-Obispo-Hotels-Inn-At-The-Pier.h18675941.Hotel-Information) ![Vespera Resort on Pismo Beach, Autograph Collection](https://images.trvl-media.com/lodging/33000000/32870000/32867400/32867377/e8728690_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Vespera Resort on Pismo Beach, Autograph Collection 147 Stimson Ave Pismo Beach CA CA $221 CA $325 total Jan 22 - Jan 23 includes taxes & fees 8.8/10 Excellent! (730 reviews) [](https://expedia.ca/San-Luis-Obispo-Hotels-Vespera-Resort-On-Pismo-Beach.h32867377.Hotel-Information) ![Avila La Fonda Hotel](https://images.trvl-media.com/lodging/2000000/1510000/1507200/1507108/c2c4905d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Avila La Fonda Hotel 101 San Miguel St Avila Beach CA CA $251 CA $283 total Feb 16 - Feb 17 includes taxes & fees 9.4/10 Exceptional! (1,004 reviews) [](https://expedia.ca/Avila-Beach-Hotels-Avila-La-Fonda-Hotel.h1507108.Hotel-Information) Still don't see what you're looking for? [See all properties in Guadalupe.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F01%2F2026&endDate=18%2F01%2F2026®ionId=6204275&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F01%2F2026&endDate=18%2F01%2F2026®ionId=6204275&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F01%2F2026&endDate=18%2F01%2F2026®ionId=6204275&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F01%2F2026&endDate=18%2F01%2F2026®ionId=6204275&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F01%2F2026&endDate=18%2F01%2F2026®ionId=6204275&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=17%2F01%2F2026&endDate=18%2F01%2F2026®ionId=6204275&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Guadalupe Murals throughout downtown celebrate the area's agricultural heritage and Mexican-American culture, with guided tours available during summer months. Dunes Centre offers exhibits on nearby Guadalupe-Nipomo Dunes, where you can explore hiking trails or join naturalist-led walks to spot rare shorebirds. [See all hotels in Guadalupe](https://www.expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31&adults=2®ionId=6204275) ![Drying seagrass and kelp on isthmus of sand between Pacific ocean and the Santa Maria river at the Rancho Guadalupe Sand Dunes Preserve on the central coast of California United States](https://images.trvl-media.com/place/6204275/c9247d8f-6401-4e4c-b1ac-8339590a517e.jpg?impolicy=fcrop&w=900&h=423&p=1&q=high) ## Top Guadalupe Hotel Reviews ## Find out more about Guadalupe ## Five Star Hotels in Guadalupe There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Guadalupe so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Guadalupe and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Guadalupe Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Guadalupe The results are in, and Guadalupe 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Guadalupe! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Guadalupe today and settle down in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Guadalupe? > - Search for the lowest price per night from CA $234 ### What makes a hotel 5 stars in Guadalupe? ### Are there any 5-star all-inclusive resorts in Guadalupe? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [2 Star Hotels in Maricopa ](https://www.expedia.ca/2Star-Maricopa-Hotels.s20-0-d182992.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Cayucos ](https://www.expedia.ca/3Star-Cayucos-Hotels.s30-0-d182965.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Edna Valley ](https://www.expedia.ca/3Star-Edna-Valley-Hotels.s30-0-d553248621593965859.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Montecito ](https://www.expedia.ca/3Star-Montecito-Santa-Barbara-Hotels.s30-n6055656-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Morro Bay ](https://www.expedia.ca/3Star-Morro-Bay-Hotels.s30-0-d8976.Travel-Guide-Filter-Hotels) - 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