Title: 5 Stars Hotels in Cayos Zapatilla, Bocas del Toro Province from CA $116 - Find Cheap Cayos Zapatilla Hotels With 5 Stars | Expedia.ca [Cayos Zapatilla Travel Guide](https://expedia.ca/Cayos-Zapatilla.dx6286134)[Hotels in Cayos Zapatilla](https://expedia.ca/Cayos-Zapatilla-Hotels.d6286134.Travel-Guide-Hotels)[Vacation Rentals in Cayos Zapatilla](https://expedia.ca/Cayos-Zapatilla-Vacation-Rentals.d6286134.Travel-Guide-VacationRentals)[Flights to Cayos Zapatilla](https://expedia.ca/Cheap-Flights-To-Cayos-Zapatilla.d6286134.Travel-Guide-Flights)[Cayos Zapatilla Car Rentals](https://expedia.ca/Car-Rentals-In-Cayos-Zapatilla.d6286134.Car-Rental-Guide)[Cayos Zapatilla Vacation Packages](https://expedia.ca/Cayos-Zapatilla.d6286134.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/2/8239fa41f2c289b46d39bd2f79231511.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Isa # 5 Stars Hotels in Cayos Zapatilla, Bocas del Toro Province from CA $116 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cayos Zapatilla 5 Star Hotels Tonight [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=6286134&startDate=2025-10-08&endDate=2025-10-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=6286134&startDate=2025-10-09&endDate=2025-10-10&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6286134&startDate=2025-10-10&endDate=2025-10-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6286134&startDate=2025-10-17&endDate=2025-10-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Cayos Zapatilla 5 Star Hotels ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Cayos-Zapatilla-Hotels.s50-0-d6286134.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Cayos-Zapatilla-Hotels.s50-0-d6286134.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Cayos Zapatilla. ![Red Frog Beach Island Resort](https://images.trvl-media.com/lodging/5000000/4030000/4027300/4027252/312e0903_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Frog Beach Island Resort Isla Bastimentos, Bocas Town, Bocas del Toro, Bastimentos, Bocas del Toro CA $373 CA $484 total Oct 9 - Oct 10 includes taxes & fees 8.8/10 Excellent! (82 reviews) [](https://expedia.ca/Isla-Bastimentos-Hotels-Red-Frog-Beach-Island-Resort.h4027252.Hotel-Information) ![NAYARA Bocas del Toro](https://images.trvl-media.com/lodging/52000000/51310000/51300100/51300004/605d473e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### NAYARA Bocas del Toro Subdivision of Bocas del toro, Isla Frangipani, Bocas del Toro [Get rates](https://expedia.ca/Hotel-Search?startDate=22%2F10%2F2025&endDate=23%2F10%2F2025&selected=51300004&PinnedHotelID=51300004&HadPinnedHotel=true®ionId=6286134) 10/10 Exceptional! (55 reviews) [](https://expedia.ca/Bocas-Del-Toro-Hotels-Bocas-Bali.h51300004.Hotel-Information) ![Akwaba Lodge](https://images.trvl-media.com/lodging/97000000/96320000/96311700/96311639/8b07e3db_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Akwaba Lodge isla solarte, Bastimentos, bocas del toro CA $105 CA $116 total Oct 9 - Oct 10 includes taxes & fees 9.6/10 Exceptional! (12 reviews) [](https://expedia.ca/Bastimentos-Hotels-Akwaba-Lodge.h96311639.Hotel-Information) Still don't see what you're looking for? [See all properties in Cayos Zapatilla.](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F10%2F2025&endDate=10%2F10%2F2025®ionId=6286134&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F10%2F2025&endDate=10%2F10%2F2025®ionId=6286134&star=50&star=50&amenities=POOL)[Spa](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F10%2F2025&endDate=10%2F10%2F2025®ionId=6286134&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F10%2F2025&endDate=10%2F10%2F2025®ionId=6286134&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F10%2F2025&endDate=10%2F10%2F2025®ionId=6286134&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=09%2F10%2F2025&endDate=10%2F10%2F2025®ionId=6286134&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Cayos Zapatilla Head to sights like Zapatilla Island as you discover the local area in Cayos Zapatilla. [See all hotels in Cayos Zapatilla](https://www.expedia.ca/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23&adults=2®ionId=6286134) ![](https://mediaim.expedia.com/destination/2/8239fa41f2c289b46d39bd2f79231511.jpg?impolicy=fcrop&w=899&h=600&p=1&q=high) Photo by Isa ## Top Cayos Zapatilla Hotel Reviews ## Find out more about Cayos Zapatilla ## Five Star Hotels in Cayos Zapatilla There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Cayos Zapatilla so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Cayos Zapatilla and get ready to be pampered like never before. #### Get a Great Deal on 5-Star Hotels in Cayos Zapatilla Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places. Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town. #### Make Your Escape to Cayos Zapatilla The results are in, and Cayos Zapatilla 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Cayos Zapatilla! Don't put off your dream vacation any longer. 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