Title: 4 Stars Hotels in Central, South Carolina from CA $218 - Find Cheap Central Hotels With 4 Stars | Expedia.ca [Central Travel Guide](https://expedia.ca/Central.dx10503)[Hotels in Central](https://expedia.ca/Central-Hotels.d10503.Travel-Guide-Hotels)[Vacation Rentals in Central](https://expedia.ca/Central-Vacation-Rentals.d10503.Travel-Guide-VacationRentals)[Flights to Central](https://expedia.ca/Cheap-Flights-To-Central.d10503.Travel-Guide-Flights)[Central Car Rentals](https://expedia.ca/Car-Rentals-In-Central.d10503.Car-Rental-Guide)[Central Vacation Packages](https://expedia.ca/Central.d10503.Destination-Travel-Guides) ![Todd Creek Falls](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central 4 Star Hotels Tonight [Apr 1 - Apr 2](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2026-04-01&endDate=2026-04-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 2 - Apr 3](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2026-04-02&endDate=2026-04-03&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=10503&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Central 4-star hotels ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (779 reviews) "Excellent stay, I highly recommend! Accommodations, location, overall vibe, great food and drinks! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $319 CA $354 total includes taxes & fees Apr 8 - Apr 9 [](https://www.expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (582 reviews) "Excellent location to visit Clemson. Staff is very friendly. Rooms are clean spacious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda CA $220 CA $244 total includes taxes & fees Apr 14 - Apr 15 [](https://www.expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7ccc39b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Double Room](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/bd9ed0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (86 reviews) "The was by far one of the best bed and breakfast places that I have ever stayed in. The house is beautiful, the rooms and spotless and the breakfast is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer Ann CA $197 CA $218 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/8d8778c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/099a6462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/00f3abbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/9c4042e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxe Keowee Key Living: Golf Views & Resort Pool [](https://www.expedia.ca/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/6608ac97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/896f48be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/580b23a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/fea470ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo: Resort Pools & Lake Access! [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) Salem 10/10 Exceptional (1 review) [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) ![Signature House, 4 Bedrooms, Patio | In-room dining](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/157c00b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/9a24528f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/63caaad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Living room](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/877220d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Hartwell Frank Howard Home Clemson [](https://www.expedia.ca/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) Anderson CA $205 CA $459 total includes taxes & fees Apr 13 - Apr 14 [](https://www.expedia.ca/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/5525119f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d3e3f6c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d726d506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/a31ab2bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Balcony: Lake Keowee Home w/ Pool Access [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) ![Family House, 4 Bedrooms, Patio, Courtyard View | Private kitchen](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/f91516fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | View from room](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/769a03d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | In-room dining](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/87cae821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/c252d911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belvedere [](https://www.expedia.ca/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) Anderson 8.0/10 Very good (1 review) "Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CANDACE [](https://www.expedia.ca/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/1a03e1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/461e3c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/3d5f6f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/9c5ca6a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Views, Pools & Marina: Lake Keowee Condo! [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/fa41c5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/be9143a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f1051c24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f8d4e496.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 5 Mi to Memorial Stadium & Beach: Modern Townhome [](https://www.expedia.ca/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) Central [](https://www.expedia.ca/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/a735e279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/8692c837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/ad6d8353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! [](https://www.expedia.ca/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Salem 10/10 Exceptional (1 review) "Property is in a great community, and it was very clean and beautifully decorated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.ca/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/4fa0f099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/0653afbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/8810e390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/cd2123cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salem Vacation Rental w/ Lake Keowee Access! [](https://www.expedia.ca/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/fb4662cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/9f6b4e3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/fc937358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/2ec7bf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Resort Condo: Waterfront Balcony [](https://www.expedia.ca/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) Salem 10/10 Exceptional (1 review) "Very clean. Amazing amenities. Lake view that takes your breath away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany [](https://www.expedia.ca/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/d76a95da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/bfd98704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/b1968ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/a2b95b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Key Condo w/ Lake Access & Community Pools! [](https://www.expedia.ca/Salem-Hotels-Keowee-Key-Condo-W-Lake-Access-Community-Pools.h108002358.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Keowee-Key-Condo-W-Lake-Access-Community-Pools.h108002358.Hotel-Information) ![Apartment (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/9fa693a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/c224b6bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/c292a0ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/69d5ed43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Keys Home w/ Mountains View & Lake Access! [](https://www.expedia.ca/Salem-Hotels-Gated-Keowee-Keys-Home-W-Mtn-View-Lake-Access.h93537133.Hotel-Information) Salem 8.0/10 Very good (1 review) "upstairs guestroom has difficult ceiling and space for taller person. Property is in great condition. Wish the queen bed was a king." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KURT [](https://www.expedia.ca/Salem-Hotels-Gated-Keowee-Keys-Home-W-Mtn-View-Lake-Access.h93537133.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/0840114c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/3fc10c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/43197a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/5d2078aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson Game Retreat: Lakefront Keowee Key Condo [](https://www.expedia.ca/Salem-Hotels-Clemson-Game-Retreat-Lakefront-Keowee-Key-Condo.h119669823.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Clemson-Game-Retreat-Lakefront-Keowee-Key-Condo.h119669823.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/5388a21f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/036e1b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/2ad3fd14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/bea2ca6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Seneca Home - 3 Mi to Memorial Stadium! [](https://www.expedia.ca/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information) Seneca [](https://www.expedia.ca/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/474920f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/83bafbb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/c278be28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/922ad3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront Seneca Vacation Rental w/ Shared Dock! [](https://www.expedia.ca/Seneca-Hotels-Lakefront-Seneca-Vacation-Rental-W-Shared-Dock.h104092180.Hotel-Information) Seneca [](https://www.expedia.ca/Seneca-Hotels-Lakefront-Seneca-Vacation-Rental-W-Shared-Dock.h104092180.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/8729946e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/6242630a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/a379d456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/574bf553.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo w/ Balcony & Resort Amenities! [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-W-Balcony-Resort-Amenities.h93537195.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Lake-Keowee-Condo-W-Balcony-Resort-Amenities.h93537195.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/3104feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/0976ca1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/80c0fa07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/3031d180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marina Villa Condo at Lake Keowee w/ Fireplace [](https://www.expedia.ca/Salem-Hotels-Lakeside-Salem-Condo-W-Balcony-Fireplace.h107264271.Hotel-Information) Salem [](https://www.expedia.ca/Salem-Hotels-Lakeside-Salem-Condo-W-Balcony-Fireplace.h107264271.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Central-Hotels.s40-0-d10503.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Central-Hotels.s40-0-d10503.Travel-Guide-Filter-Hotels) ## Learn more about Central Nestled between Clemson University and Southern Wesleyan University, this college town offers charming Main Street shops and Southern Wesleyan's campus trails. Outdoor enthusiasts can enjoy Lake Keowee's pristine waters or catch Tigers football games in nearby Clemson during fall weekends. [See all hotels in Central](https://www.expedia.ca/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16&adults=2®ionId=10503) ![Todd Creek Falls](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Central Hotel Reviews ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "Limited menu available on site but many places nearby in walking distance." [](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![The Abernathy of Clemson](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7_y.jpg) ### The Abernathy of Clemson 10/10 Excellent "Everything was great, we had a very late arrival and they greeted us with a smile!" [](https://expedia.ca/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ## Find out more about Central If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Central are calling your name. Known for providing first-rate service in amazing locations, each of the Central 4 Stars hotels lets discerning travelers bask in an unforgettable experience. Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day. It’s all waiting for you at the top four star hotels in Central. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Central, South Carolina, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Central hotels with 4 Stars provide everything you need to unwind in style. ## Frequently asked questions ### What are the best 4-star hotels in Central? ### How much does it cost to stay in a 4-star hotel in Central? > - Search for the lowest price from CA $218 ### What's the difference between 5-star and 4-star hotels in Central? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [3 Star Hotels in Belvedere ](https://www.expedia.ca/3Star-Belvedere-Hotels.s30-0-d553248634999443381.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Blacksburg ](https://www.expedia.ca/3Star-Blacksburg-Hotels.s30-0-d183936.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Greenville ](https://www.expedia.ca/3Star-Greenville-Hotels.s30-0-d1388.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Highland ](https://www.expedia.ca/3Star-Highland-Hotels.s30-0-d553248635975852355.Travel-Guide-Filter-Hotels) - 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