CA $427 Cheap Flights from Syracuse (SYR) to Sioux Falls (FSD)

View CA $427 flight on Tue, Jun 16, 2026Opens in a new window

Popular airlines from Hancock Intl. Airport (SYR) to Sioux Falls Regional Airport (FSD)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Syracuse (SYR) to Sioux Falls (FSD)

Prices were available within the past 7 days and start at CA $427 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How do I find cheap flights from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
To find a cheap flight from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
There are approximately 21 connecting flights per day from Syracuse, NY (SYR-Hancock Intl.) (SYR) to Sioux Falls, SD (FSD-Sioux Falls Regional) (FSD). Some common connection points include O'Hare Intl. (ORD), Washington Dulles Intl. (IAD), and Detroit Metropolitan Wayne County (DTW).
What is the earliest flight from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The earliest flight from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) typically departs at approximately 5:10 AM local time, operated by Delta. This is a seasonal service active in March. An early departure like this can help you maximize your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
You'll typically find the most flights from Syracuse Hancock Intl. (SYR) to Sioux Falls Regional (FSD) on a Sunday, with around 20 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United Airlines, Delta Air Lines, and American Airlines. Flight options are notably more on Sundays compared to other days.
What are the most popular departure times for flights from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
The most popular departure times for flights from Syracuse Hancock Intl. (SYR) to Sioux Falls Regional (FSD) are in the early morning, from 6am to 9am. About 29% of passengers prefer this time. Many major carriers, including American Airlines, United Airlines and Delta Air Lines, offer flights during this window. This timing works well because it allows you to get an early start on your travel day and arrive at your destination with plenty of time.
How long does it take to fly from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
Flights from SYR to FSD with one stop typically take around 5 hours 30 minutes, covering approximately 1,034 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
Select the "Business class" and "First class" filters when looking for SYR to FSD flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight with Expedia?
It's easy to earn miles on a Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Sioux Falls from Hancock Intl. (SYR)?
If you're planning to travel to Sioux Falls from Hancock Intl. (SYR), you can fly into Sioux Falls Regional (FSD) Some flights may connect through major hubs like LaGuardia (LGA), Detroit Metropolitan Wayne County (DTW), Washington Dulles Intl. (IAD) before reaching Sioux Falls. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) at the last minute?
Typically, booking a last minute flight from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight and hotel package?
Securing a Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional)?
If you booked your Syracuse, NY (SYR-Hancock Intl.) to Sioux Falls, SD (FSD-Sioux Falls Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Hancock Intl.
Destination airport
Sioux Falls Regional
Distance
1654 km

Book with confidence

North Syracuse to Sioux Falls Flights

The easy way to book your flights from Syracuse to Sioux Falls 

With Expedia, it’s simple to find and book flights to Sioux Falls from Syracuse whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 4 airlines that cover this route. There are nonstop flights to Sioux Falls Regional, too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Syracuse to Sioux Falls today, tomorrow, or this week.  

 

Save dollars with cheap flights from Hancock Intl., SYR to Sioux Falls Regional, FSD 

Sort your search results by price to find great deals on your flight from Syracuse to Sioux Falls—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Sioux Falls from Syracuse currently is just rising to .  

Here are more money-saving tips: 

  • Fly in when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Sioux Falls  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Sioux Falls from Syracuse 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Sioux Falls with Expedia today.

North Syracuse to Sioux Falls Flights

Explore a world of travel with Expedia

*Available to Expedia members.