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CA $276 Cheap Flights from Orange County (SNA) to St. Louis (STL)

View CA $276 flight on Mon, Oct 26, 2026Opens in a new window

Popular airlines from John Wayne Airport (SNA) to Lambert-St. Louis International Airport (STL)

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Cheap flights from Orange County (SNA) to St. Louis (STL)

Prices were available within the past 7 days and start at CA $276 for one-way flights and CA $551 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Oct 26 - Wed, Oct 28
SNA
Orange County
STL
St. Louis
CA $551 Roundtrip, found 8 hours ago
CA $551
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Oct 26 from Orange County to St. Louis, returning Wed, Oct 28, priced at CA $551 found 8 hours ago
American Airlines
Mon, Oct 26 - Wed, Oct 28
SNA
Orange County
STL
St. Louis
CA $573 Roundtrip, found 8 hours ago
CA $573
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Oct 26 from Orange County to St. Louis, returning Wed, Oct 28, priced at CA $573 found 8 hours ago
American Airlines
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $577 Roundtrip, found 8 hours ago
CA $577
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $577 found 8 hours ago
American Airlines
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $582 Roundtrip, found 8 hours ago
CA $582
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $582 found 8 hours ago
American Airlines
Mon, Oct 26 - Wed, Oct 28
SNA
Orange County
STL
St. Louis
CA $594 Roundtrip, found 8 hours ago
CA $594
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Oct 26 from Orange County to St. Louis, returning Wed, Oct 28, priced at CA $594 found 8 hours ago
American Airlines
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $604 Roundtrip, found 8 hours ago
CA $604
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $604 found 8 hours ago
American Airlines
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $607 Roundtrip, found 8 hours ago
CA $607
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $607 found 8 hours ago
Alaska Airlines
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $610 Roundtrip, found 8 hours ago
CA $610
Roundtrip
found 8 hours ago
Select Alaska Airlines flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $610 found 8 hours ago
United
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $631 Roundtrip, found 8 hours ago
CA $631
Roundtrip
found 8 hours ago
Select United flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $631 found 8 hours ago
Delta
Thu, Oct 1 - Mon, Oct 5
SNA
Orange County
STL
St. Louis
CA $642 Roundtrip, found 8 hours ago
CA $642
Roundtrip
found 8 hours ago
Select Delta flight, departing Thu, Oct 1 from Orange County to St. Louis, returning Mon, Oct 5, priced at CA $642 found 8 hours ago

Frequently asked questions

How much does a flight from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) cost?
You can find one-way and return flights from SNA to STL with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when SNA to STL ticket fares go up or down.
What is the cheapest month to fly from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
August is typically the cheapest month to fly from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.), with average return fares around CA$539. August often sees lower prices as the peak summer travel season winds down, and families might be looking for last-minute trips before school starts. Other cheap months to fly from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) include February and September.
Which airlines fly direct from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Enter SNA to STL and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting return flights from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.), with prices starting from around CA$354 for flights that can be booked for departure within the next year, with a layover in Harry Reid Intl. (LAS). These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
To find a cheap flight from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The cheapest months to fly from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) are typically August and February, with average return flights around CA$539. These months often offer a good balance of lower prices, allowing you to find more affordable fares for your trip.
How many flights per day from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
There are approximately 66 connecting flights per day from John Wayne (SNA) to Lambert-St. Louis Intl. (STL). Some common connection points include Seattle - Tacoma Intl. (SEA), Denver Intl. (DEN), and Portland Intl. (PDX).
What is the earliest flight from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The earliest flight from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) typically departs around 6:40 AM. This service is operated by American Airlines. Please note that this is a seasonal service, active only in April. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
You'll typically find the most flights from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) on a Thursday, with around 63 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include Southwest Airlines, Alaska Airlines, and United. Flight schedules are quite consistent throughout the week, so you'll have plenty of options regardless of the day you choose to fly.
What are the most popular departure times for flights from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
The most popular departure times for flights from John Wayne (SNA) to Lambert-St. Louis Intl. (STL) are in the early morning, from 6am to 9am. Many major carriers, including Southwest Airlines, American Airlines and United, offer flights during this window. Many travellers prefer these early flights to get a head start on their day at their destination.
How long does it take to fly from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
There are no nonstop flights from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.), a distance of approximately 2520 kilometres. For flights with one stop, you can expect the journey to typically take around 6 hours 48 minutes. If your flight has two or more stops, the travel time will generally be longer, averaging about 8 hours 30 minutes. Keep in mind that actual flight times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
Yes, you can fly business class or first class between SNA and STL. Airlines that offer business class service on this route include:

  • Frontier Airlines
  • Delta

First class cabins are available on Alaska Airlines, Delta, United, and American Airlines.
How do I earn miles on a Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight with Expedia?
It's easy to earn miles on a Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for St. Louis, MO (STL) from Orange County, CA (SNA)?
If you're planning to travel to St. Louis from John Wayne (SNA), you can fly directly into Lambert-St. Louis Intl. (STL). Some flights may connect through major hubs like Harry Reid International Airport (LAS), Sky Harbor Intl. (PHX), or Denver Intl. (DEN) before reaching St. Louis. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) at the last minute?
Typically, booking a last minute flight from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package?
Securing a Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.)?
If you booked your Orange County, CA (SNA-John Wayne) to St. Louis, MO (STL-Lambert-St. Louis Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
John Wayne
Destination airport
Lambert-St. Louis Intl.
Roundtrip price
CA $551
Distance
2505 km

Book with confidence

Santa Ana to St. Louis Flights

The easy way to book your flights from Orange County to St. Louis 

With Expedia, it’s simple to find and book flights to St. Louis from Orange County whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Lambert-St. Louis Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Orange County to St. Louis today, tomorrow, or this week.  

 

Save dollars with cheap flights from John Wayne, SNA to Lambert-St. Louis Intl., STL 

Sort your search results by price to find great deals on your flight from Orange County to St. Louis—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to St. Louis from Orange County currently is just CA $551 rising to CA $642.  

Here are more money-saving tips: 

  • Fly in October when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to St. Louis  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to St. Louis from Orange County 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to St. Louis with Expedia today.

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