A statue on a pedestal overlooking a cityscape with various buildings and a clear sky.

CA $229 Cheap Flights from Panama City (PTY) to Cali (CLO)

View CA $229 flight on Fri, Sep 25, 2026Opens in a new window

Popular airlines from Tocumen Intl. Airport (PTY) to Alfonso Bonilla Aragon Intl. Airport (CLO)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Panama City (PTY) to Cali (CLO)

Prices were available within the past 7 days and start at CA $229 for one-way flights and CA $519 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Thu, Oct 1 - Fri, Oct 9
PTY
Panama City
CLO
Cali
CA $519 Roundtrip, found 1 day ago
CA $519
Roundtrip
found 1 day ago
Select avianca flight, departing Thu, Oct 1 from Panama City to Cali, returning Fri, Oct 9, priced at CA $519 found 1 day ago
avianca
Wed, Apr 7 - Mon, Apr 19
PTY
Panama City
CLO
Cali
CA $520 Roundtrip, found 2 days ago
CA $520
Roundtrip
found 2 days ago
Select avianca flight, departing Wed, Apr 7 from Panama City to Cali, returning Mon, Apr 19, priced at CA $520 found 2 days ago
Copa
Thu, Dec 3 - Sun, Dec 20
PTY
Panama City
CLO
Cali
CA $586 Roundtrip, found 4 days ago
CA $586
Roundtrip
found 4 days ago
Select Copa flight, departing Thu, Dec 3 from Panama City to Cali, returning Sun, Dec 20, priced at CA $586 found 4 days ago
avianca
Fri, Dec 18 - Sun, Jan 17
PTY
Panama City
CLO
Cali
CA $587 Roundtrip, found 1 day ago
CA $587
Roundtrip
found 1 day ago
Select avianca flight, departing Fri, Dec 18 from Panama City to Cali, returning Sun, Jan 17, priced at CA $587 found 1 day ago
avianca
Thu, Dec 10 - Sun, Jan 10
PTY
Panama City
CLO
Cali
CA $589 Roundtrip, found 2 days ago
CA $589
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Dec 10 from Panama City to Cali, returning Sun, Jan 10, priced at CA $589 found 2 days ago
avianca
Sun, Jan 3 - Fri, Jan 15
PTY
Panama City
CLO
Cali
CA $598 Roundtrip, found 4 days ago
CA $598
Roundtrip
found 4 days ago
Select avianca flight, departing Sun, Jan 3 from Panama City to Cali, returning Fri, Jan 15, priced at CA $598 found 4 days ago
avianca
Thu, Oct 29 - Mon, Nov 2
PTY
Panama City
CLO
Cali
CA $610 Roundtrip, found 4 days ago
CA $610
Roundtrip
found 4 days ago
Select avianca flight, departing Thu, Oct 29 from Panama City to Cali, returning Mon, Nov 2, priced at CA $610 found 4 days ago
avianca
Fri, Dec 18 - Sun, Jan 17
PTY
Panama City
CLO
Cali
CA $645 Roundtrip, found 1 day ago
CA $645
Roundtrip
found 1 day ago
Select avianca flight, departing Fri, Dec 18 from Panama City to Cali, returning Sun, Jan 17, priced at CA $645 found 1 day ago
avianca
Thu, Dec 10 - Sun, Jan 10
PTY
Panama City
CLO
Cali
CA $647 Roundtrip, found 2 days ago
CA $647
Roundtrip
found 2 days ago
Select avianca flight, departing Thu, Dec 10 from Panama City to Cali, returning Sun, Jan 10, priced at CA $647 found 2 days ago
avianca
Wed, Dec 16 - Tue, Jan 5
PTY
Panama City
CLO
Cali
CA $656 Roundtrip, found 4 days ago
CA $656
Roundtrip
found 4 days ago
Select avianca flight, departing Wed, Dec 16 from Panama City to Cali, returning Tue, Jan 5, priced at CA $656 found 4 days ago
avianca
Mon, Sep 28 - Mon, Oct 5
PTY
Panama City
CLO
Cali
CA $668 Roundtrip, found 5 days ago
CA $668
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Sep 28 from Panama City to Cali, returning Mon, Oct 5, priced at CA $668 found 5 days ago

Find the cheapest month to fly from Panama City (PTY) to Cali (CLO)

March is typically the cheapest month to fly

From CA $346 - CA $611 per traveller.

Frequently asked questions

How much does a flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) cost?
You can find cheap one-way flights from CA $229 and cheap return flights from CA $519 PTY to CLO with Expedia. One-way flights typically cost between CA$302 and CA$612. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when PTY to CLO ticket fares go up or down.
What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
The cheapest months to fly from PTY to CLO are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
Only one airline offers direct flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.). Copa operates 31 direct flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) every week.
What is the cheapest airline that flies from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
Copa is one of the cheapest airlines offering nonstop return flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.), with tickets starting from around CA$333 for flights that can be booked for departure within the next year. Avianca is one of the cheapest airlines offering connecting return flights, with tickets starting from around CA$401. These prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
The best airline to fly with from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) will differ from traveler to traveler. If you like to fly early, Copa offers early morning flights. If price is the most important factor, Copa typically offers the lowest fares. Avianca offers the most daily flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
You'll find around 4 nonstop flights per day from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.). For even more choices, look at flights that include layovers, as there are approximately 5 connecting flights per day. Some common connection points include El Dorado Intl. (BOG), Mexico City Intl. (MEX), and Miami Intl. (MIA).
What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
The earliest flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) typically departs around 2:55 AM local time. This flight is operated by Avianca. This is a seasonal service, active in January, February, March, October, November, and December. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
You'll typically find the most flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) on a Friday, with around 8 flights available. This gives you a good selection for your travel plans. Major airlines on this route include Copa, Avianca, and Aeromexico. Flight schedules are quite consistent throughout the week, so you'll have plenty of options no matter which day you choose to fly.
What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
The most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) are in the afternoon, from 3pm to 6pm. Many major carriers, including Avianca, Copa and Aeromexico, offer flights during this window. Many travellers prefer this time as it allows for a productive morning before heading to the airport, and you'll arrive in Cali in the evening.
How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
A direct flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) typically takes around 1 hour 45 minutes. This route covers a distance of approximately 698 kilometres. If you opt for a flight with one stop, your travel time will be significantly longer, usually around 5 hours 30 minutes. Flights with two or more stops generally take about 11 hours. Keep in mind that actual flight times can vary due to factors like wind patterns and air traffic, so it's always a good idea to allow for some extra time when planning your journey.
Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
Yes, you can fly business class between PTY and CLO. Airlines that offer business class service on this route include:
  • Avianca
  • Copa
  • Aeromexico
How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight with Expedia?
It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Cali (CLO) from Panama City (PTY)?
If you're planning to travel to Cali from Tocumen Intl. (PTY), you can fly directly into Alfonso Bonilla Aragon Intl. (CLO) which offers international flights and connections. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) at the last minute?
Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight and hotel package?
Securing a Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.)?
If you booked your Panama City (PTY-Tocumen Intl.) to Cali (CLO-Alfonso Bonilla Aragon Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Tocumen Intl.
Destination airport
Alfonso Bonilla Aragon Intl.
Airlines serving
avianca
Roundtrip price
CA $518
Distance
694 km
Average flight time
1 hour 38 mins

Book with confidence

Tocumen to Cali Flights

The easy way to book your flights from Panama City to Cali 

With Expedia, it’s simple to find and book flights to Cali from Panama City whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Alfonso Bonilla Aragon Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Panama City to Cali today, tomorrow, or this week.  

 

Save dollars with cheap flights from Tocumen Intl., PTY to Alfonso Bonilla Aragon Intl., CLO 

Sort your search results by price to find great deals on your flight from Panama City to Cali—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Cali from Panama City currently is just CA $519 rising to CA $749.  

Here are more money-saving tips: 

  • Fly in October when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Cali  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Cali from Panama City 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Cali with Expedia today.

Tocumen to Cali Flights
*Available to Expedia members.