A city skyline at dusk with illuminated buildings and a calm river in the foreground.

CA $319 Cheap Flights from La Crosse (LSE) to Detroit (DTW)

View CA $319 flight on Sat, Oct 17, 2026Opens in a new window

Popular airlines from La Crosse, WI (LSE-La Crosse Municipal) to Detroit Metropolitan Wayne County Airport (DTW)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from La Crosse (LSE) to Detroit (DTW)

Prices were available within the past 7 days and start at CA $319 for one-way flights and CA $739 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Oct 24 - Sat, Nov 7
LSE
La Crosse
DTW
Detroit
CA $739 Roundtrip, found 3 days ago
CA $739
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Oct 24 from La Crosse to Detroit, returning Sat, Nov 7, priced at CA $739 found 3 days ago
American Airlines
Wed, Oct 21 - Sat, Nov 7
LSE
La Crosse
DTW
Detroit
CA $802 Roundtrip, found 3 days ago
CA $802
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Oct 21 from La Crosse to Detroit, returning Sat, Nov 7, priced at CA $802 found 3 days ago
American Airlines
Thu, Oct 22 - Sat, Nov 7
LSE
La Crosse
DTW
Detroit
CA $812 Roundtrip, found 3 days ago
CA $812
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Oct 22 from La Crosse to Detroit, returning Sat, Nov 7, priced at CA $812 found 3 days ago
American Airlines
Tue, Oct 13 - Tue, Oct 27
LSE
La Crosse
DTW
Detroit
CA $830 Roundtrip, found 3 days ago
CA $830
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Oct 13 from La Crosse to Detroit, returning Tue, Oct 27, priced at CA $830 found 3 days ago
American Airlines
Wed, Nov 4 - Sat, Nov 14
LSE
La Crosse
DTW
Detroit
CA $837 Roundtrip, found 3 days ago
CA $837
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Nov 4 from La Crosse to Detroit, returning Sat, Nov 14, priced at CA $837 found 3 days ago
American Airlines
Mon, Oct 26 - Sat, Oct 31
LSE
La Crosse
DTW
Detroit
CA $853 Roundtrip, found 3 days ago
CA $853
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Oct 26 from La Crosse to Detroit, returning Sat, Oct 31, priced at CA $853 found 3 days ago
American Airlines
Sat, Nov 28 - Sat, Dec 12
LSE
La Crosse
DTW
Detroit
CA $858 Roundtrip, found 3 days ago
CA $858
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 28 from La Crosse to Detroit, returning Sat, Dec 12, priced at CA $858 found 3 days ago
American Airlines
Mon, Oct 26 - Sat, Nov 7
LSE
La Crosse
DTW
Detroit
CA $860 Roundtrip, found 3 days ago
CA $860
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Oct 26 from La Crosse to Detroit, returning Sat, Nov 7, priced at CA $860 found 3 days ago
American Airlines
Tue, Oct 6 - Sat, Oct 17
LSE
La Crosse
DTW
Detroit
CA $864 Roundtrip, found 3 days ago
CA $864
Roundtrip
found 3 days ago
Select American Airlines flight, departing Tue, Oct 6 from La Crosse to Detroit, returning Sat, Oct 17, priced at CA $864 found 3 days ago
American Airlines
Sat, Nov 14 - Mon, Nov 30
LSE
La Crosse
DTW
Detroit
CA $868 Roundtrip, found 3 days ago
CA $868
Roundtrip
found 3 days ago
Select American Airlines flight, departing Sat, Nov 14 from La Crosse to Detroit, returning Mon, Nov 30, priced at CA $868 found 3 days ago

Alternative airports near Detroit

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Detroit Metropolitan Wayne County DTW. Cheapest option available. Average driving time to city centre is 26 minutes. Flights from CA $802
DTW
Detroit Metropolitan Wayne County
Cheapest
Average driving time to city centre26 min
Flights from CA $802

Frequently asked questions

How much does a flight from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) cost?
You can find one-way and return flights from LSE to DTW with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when LSE to DTW ticket fares go up or down.
What is the cheapest month to fly from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
The cheapest months to fly from LSE to DTW are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
Enter LSE to DTW and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
American Airlines is one of the cheapest airlines offering connecting return flights from La Crosse Municipal (LSE) to Detroit Metropolitan Wayne County (DTW), with tickets starting from around CA$480 for flights that can be booked for departure within the next year. These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
To find a cheap flight from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
There are approximately 5 connecting flights per day from La Crosse Municipal (LSE) to Detroit Metropolitan Wayne County (DTW). A common connection point includes O'Hare Intl. (ORD).
What is the earliest flight from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
The earliest flight from La Crosse Municipal (LSE) to Detroit Metropolitan Wayne County (DTW) typically departs around 5:05 AM local time. This flight is operated by American Airlines. This is a seasonal service active in March. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
You'll find the most flights from La Crosse Municipal (LSE) to Detroit Metropolitan Wayne County (DTW) on a Monday, with around 3 flights available. This gives you a good selection of options for your travel plans. American Airlines offers service on this route. Flight schedules are consistent throughout the week, so you'll generally find similar options on other weekdays as well.
What are the most popular departure times for flights from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
The most popular departure times for flights from La Crosse Municipal (LSE) to Detroit Metropolitan Wayne County (DTW) are in the evening, from 6pm to 9pm. American Airlines offers flights during this window. Many travellers prefer these times because you can finish your day in La Crosse before your flight and arrive in Detroit ready for the next day.
How long does it take to fly from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
There are no nonstop flights from La Crosse Municipal (LSE) to Detroit Metropolitan Wayne County (DTW). The distance between these two airports is about 668 kilometres. Flights with one stop typically take around 6 hours 18 minutes. If you opt for flights with two or more stops, your travel time will be longer, usually around 8 hours 18 minutes. Keep in mind that these are average times, and your actual flight duration can vary depending on the specific routing, layover times, and even weather conditions.
Can you fly business or first class from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
You can fly first class between LSE and DTW. First class cabins are available on American Airlines.
How do I earn miles on a La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) flight with Expedia?
It's easy to earn miles on a La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Detroit, MI (DTW) from La Crosse, WI (LSE)?
If you're planning to travel to Detroit from La Crosse Municipal (LSE), you can fly directly into Detroit Metropolitan Wayne County (DTW). Some flights may connect through major hubs like O'Hare Intl. (ORD) before reaching Detroit. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) at the last minute?
Typically, booking a last minute flight from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) flight and hotel package?
Securing a La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County)?
If you booked your La Crosse, WI (LSE-La Crosse Municipal) to Detroit, MI (DTW-Detroit Metropolitan Wayne County) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
La Crosse Municipal
Destination airport
Detroit Metropolitan Wayne County
Roundtrip price
CA $738
Distance
664 km

Book with confidence

La Crosse to Detroit Flights

The easy way to book your flights from La Crosse to Detroit 

With Expedia, it’s simple to find and book flights to Detroit from La Crosse whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Detroit Metropolitan Wayne County, too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from La Crosse to Detroit today, tomorrow, or this week.  

 

Save dollars with cheap flights from La Crosse Municipal, LSE to Detroit Metropolitan Wayne County, DTW 

Sort your search results by price to find great deals on your flight from La Crosse to Detroit—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Detroit from La Crosse currently is just CA $739 rising to CA $868.  

Here are more money-saving tips: 

  • Fly in October when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Detroit  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Detroit from La Crosse 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Detroit with Expedia today.

La Crosse to Detroit Flights

Explore a world of travel with Expedia

*Available to Expedia members.