A plaza with a large building featuring a dome and spires, surrounded by trees and people.

CA $231 Cheap Flights from Cusco (CUZ) to Medellín (MDE)

View CA $231 flight on Thu, Sep 10, 2026Opens in a new window

Popular airlines from Alejandro Velasco Astete Intl. Airport (CUZ) to Jose Maria Cordova Intl. Airport (MDE)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Cusco (CUZ) to Medellín (MDE)

Prices were available within the past 7 days and start at CA $231 for one-way flights and CA $614 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Sat, Aug 22 - Wed, Aug 26
CUZ
Cusco
MDE
Medellín
CA $614 Roundtrip, found 5 days ago
CA $614
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Aug 22 from Cusco to Medellín, returning Wed, Aug 26, priced at CA $614 found 5 days ago
Jetsmart SPA
Sat, Aug 22 - Wed, Aug 26
CUZ
Cusco
MDE
Medellín
CA $624 Roundtrip, found 5 days ago
CA $624
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Aug 22 from Cusco to Medellín, returning Wed, Aug 26, priced at CA $624 found 5 days ago
Jetsmart SPA
Sat, Aug 22 - Wed, Aug 26
CUZ
Cusco
MDE
Medellín
CA $647 Roundtrip, found 5 days ago
CA $647
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Aug 22 from Cusco to Medellín, returning Wed, Aug 26, priced at CA $647 found 5 days ago
Jetsmart SPA
Sat, Aug 22 - Wed, Aug 26
CUZ
Cusco
MDE
Medellín
CA $657 Roundtrip, found 5 days ago
CA $657
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Aug 22 from Cusco to Medellín, returning Wed, Aug 26, priced at CA $657 found 5 days ago
Jetsmart SPA
Mon, Aug 24 - Fri, Aug 28
CUZ
Cusco
MDE
Medellín
CA $688 Roundtrip, found 2 days ago
CA $688
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Mon, Aug 24 from Cusco to Medellín, returning Fri, Aug 28, priced at CA $688 found 2 days ago
Jetsmart SPA
Mon, Aug 24 - Fri, Aug 28
CUZ
Cusco
MDE
Medellín
CA $706 Roundtrip, found 2 days ago
CA $706
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Mon, Aug 24 from Cusco to Medellín, returning Fri, Aug 28, priced at CA $706 found 2 days ago
LATAM Airlines Group
Mon, Aug 24 - Fri, Aug 28
CUZ
Cusco
MDE
Medellín
CA $849 Roundtrip, found 2 days ago
CA $849
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Aug 24 from Cusco to Medellín, returning Fri, Aug 28, priced at CA $849 found 2 days ago
LATAM Airlines Group
Sat, Aug 22 - Wed, Aug 26
CUZ
Cusco
MDE
Medellín
CA $852 Roundtrip, found 5 days ago
CA $852
Roundtrip
found 5 days ago
Select LATAM Airlines Group flight, departing Sat, Aug 22 from Cusco to Medellín, returning Wed, Aug 26, priced at CA $852 found 5 days ago
LATAM Airlines Group
Mon, Aug 24 - Fri, Aug 28
CUZ
Cusco
MDE
Medellín
CA $866 Roundtrip, found 2 days ago
CA $866
Roundtrip
found 2 days ago
Select LATAM Airlines Group flight, departing Mon, Aug 24 from Cusco to Medellín, returning Fri, Aug 28, priced at CA $866 found 2 days ago
avianca
Sat, Aug 22 - Wed, Aug 26
CUZ
Cusco
MDE
Medellín
CA $919 Roundtrip, found 5 days ago
CA $919
Roundtrip
found 5 days ago
Select avianca flight, departing Sat, Aug 22 from Cusco to Medellín, returning Wed, Aug 26, priced at CA $919 found 5 days ago

Find the cheapest month to fly from Cusco (CUZ) to Medellín (MDE)

May is typically the cheapest month to fly

From CA $466 - CA $641 per traveller.

Frequently asked questions

How much does a flight from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) cost?
You can find cheap one-way flights from CA $231 and cheap return flights from CA $614 CUZ to MDE with Expedia. One-way flights typically cost between CA$376 and CA$1095. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when CUZ to MDE ticket fares go up or down.
What is the cheapest month to fly from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
The cheapest months to fly from CUZ to MDE are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Cusco (CUZ) to Medellín (MDE)?
Enter CUZ to MDE and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Cusco (CUZ) to Medellín (MDE)?
To find a cheap flight from Cusco (CUZ)Medellín (MDE), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
There are approximately 25 connecting flights per day from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.). Some common connection points include Jorge Chavez Intl. (LIM), El Dorado Intl. (BOG), and El Alto Intl. (LPB).
What is the earliest flight from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
The earliest flight from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) typically departs around 12:05 AM. This service is operated by LATAM Airlines Group and runs year-round, active in January, February, March, April, May, June, July, August, September, November, and December. An early departure like this can be great for maximizing your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
You'll find the most flights from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) on a Wednesday, with around 18 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include LATAM Airlines Group, Avianca, and Skyways. Looking at the week, Wednesday has notably more flight options compared to other days, ensuring you have plenty of choices.
What are the most popular departure times for flights from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
The most popular departure times for flights from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) are between 12pm and 3pm. Many major carriers, including Avianca and LATAM Airlines Group, offer flights during this window. Many travellers prefer this time as it allows for a relaxed morning before heading to the airport and an afternoon arrival at your destination.
How long does it take to fly from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
There are no nonstop flights from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.). The distance between these two cities is approximately 2,226 kilometres. Flights with one stop typically take around 6 hours 30 minutes, while flights with two or more stops usually take about 12 hours 30 minutes. Keep in mind that these are average travel times, and the actual duration can vary depending on the specific routing, layover times, and factors like weather conditions.
Can you fly business or first class from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.)?
You can fly business class between CUZ and MDE. Airlines that offer business class service on this route include:
  • Avianca
How do I earn miles on a Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) flight with Expedia?
It's easy to earn miles on a Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Medellín (MDE) from Cusco (CUZ)?
If you're planning to travel to Medellin from Alejandro Velasco Astete Intl. (CUZ), you can fly directly into Jose Maria Cordova Intl. (MDE). Some flights may connect through major hubs like Jorge Chavez Intl. (LIM), El Alto Intl. (LPB), or Rodriguez Ballon Intl. (AQP) before reaching Medellin. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) at the last minute?
Typically, booking a last minute flight from Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) flight and hotel package?
Securing a Cusco (CUZ-Alejandro Velasco Astete Intl.) to Medellín (MDE-José María Córdova Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Cusco (CUZ) to Medellín (MDE)?
If you booked your Cusco (CUZ)Medellín (MDE) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Alejandro Velasco Astete Intl.
Destination airport
José María Córdova Intl.
Roundtrip price
CA $613
Distance
2212 km

Book with confidence

Cusco to Rionegro Flights

The easy way to book your flights from Cusco to Medellín 

With Expedia, it’s simple to find and book flights to Medellín from Cusco whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to José María Córdova Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Cusco to Medellín today, tomorrow, or this week.  

 

Save dollars with cheap flights from Alejandro Velasco Astete Intl., CUZ to José María Córdova Intl., MDE 

Sort your search results by price to find great deals on your flight from Cusco to Medellín—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Medellín from Cusco currently is just CA $614 rising to CA $919.  

Here are more money-saving tips: 

  • Fly in August when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Medellín  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Medellín from Cusco 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Medellín with Expedia today.

Cusco to Rionegro Flights

Explore a world of travel with Expedia

*Available to Expedia members.