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CA $203 Cheap Flights from Buffalo (BUF) to Knoxville (TYS)

View CA $203 flight on Wed, Sep 30, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Alcoa - Knoxville Airport (TYS)

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Cheap flights from Buffalo (BUF) to Knoxville (TYS)

Prices were available within the past 7 days and start at CA $203 for one-way flights and CA $405 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Oct 6 - Tue, Oct 13
BUF
Buffalo
TYS
Knoxville
CA $405 Roundtrip, found 3 hours ago
CA $405
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Oct 6 from Buffalo to Knoxville, returning Tue, Oct 13, priced at CA $405 found 3 hours ago
Delta
Wed, Oct 21 - Fri, Oct 30
BUF
Buffalo
TYS
Knoxville
CA $406 Roundtrip, found 1 day ago
CA $406
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Oct 21 from Buffalo to Knoxville, returning Fri, Oct 30, priced at CA $406 found 1 day ago
Delta
Thu, Oct 1 - Thu, Oct 8
BUF
Buffalo
TYS
Knoxville
CA $423 Roundtrip, found 3 hours ago
CA $423
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Oct 1 from Buffalo to Knoxville, returning Thu, Oct 8, priced at CA $423 found 3 hours ago
Delta
Thu, Oct 22 - Fri, Oct 30
BUF
Buffalo
TYS
Knoxville
CA $424 Roundtrip, found 1 day ago
CA $424
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Oct 22 from Buffalo to Knoxville, returning Fri, Oct 30, priced at CA $424 found 1 day ago
Delta
Wed, Sep 9 - Fri, Sep 11
BUF
Buffalo
TYS
Knoxville
CA $431 Roundtrip, found 4 days ago
CA $431
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Sep 9 from Buffalo to Knoxville, returning Fri, Sep 11, priced at CA $431 found 4 days ago
Delta
Thu, Oct 1 - Mon, Oct 5
BUF
Buffalo
TYS
Knoxville
CA $440 Roundtrip, found 2 days ago
CA $440
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Oct 1 from Buffalo to Knoxville, returning Mon, Oct 5, priced at CA $440 found 2 days ago
Delta
Thu, Oct 1 - Thu, Oct 8
BUF
Buffalo
TYS
Knoxville
CA $441 Roundtrip, found 3 hours ago
CA $441
Roundtrip
found 3 hours ago
Select Delta flight, departing Thu, Oct 1 from Buffalo to Knoxville, returning Thu, Oct 8, priced at CA $441 found 3 hours ago
Delta
Tue, Oct 6 - Fri, Oct 16
BUF
Buffalo
TYS
Knoxville
CA $448 Roundtrip, found 3 hours ago
CA $448
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Oct 6 from Buffalo to Knoxville, returning Fri, Oct 16, priced at CA $448 found 3 hours ago
American Airlines
Fri, Oct 23 - Fri, Oct 30
BUF
Buffalo
TYS
Knoxville
CA $450 Roundtrip, found 8 hours ago
CA $450
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Fri, Oct 23 from Buffalo to Knoxville, returning Fri, Oct 30, priced at CA $450 found 8 hours ago
United
Thu, Aug 27 - Mon, Aug 31
BUF
Buffalo
TYS
Knoxville
CA $468 Roundtrip, found 2 days ago
CA $468
Roundtrip
found 2 days ago
Select United flight, departing Thu, Aug 27 from Buffalo to Knoxville, returning Mon, Aug 31, priced at CA $468 found 2 days ago

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) cost?
You can find cheap one-way flights from CA $203 and cheap return flights from CA $405 BUF to TYS with Expedia. One-way flights typically cost between CA$211 and CA$910, and return flights often range between CA$575 and CA$1509. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when BUF to TYS ticket fares go up or down.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The cheapest months to fly from BUF to TYS are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Enter BUF to TYS and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Southwest Airlines is one of the cheapest airlines offering connecting return flights from Buffalo Niagara Intl. (BUF) to McGhee Tyson (TYS), with prices starting from around CA$379 for flights that can be booked for departure within the next year. These flights typically include a layover in Baltimore Washington Intl. Thurgood Marshall (BWI). Prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
There are approximately 51 connecting flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson). Some common connection points include O'Hare Intl. (ORD), Washington Dulles Intl. (IAD), and Baltimore Washington Intl. Thurgood Marshall (BWI).
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) typically departs around 5:00 AM. This flight is operated by American Airlines. This is a seasonal service active only in May. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
You'll typically find the most flights from Buffalo Niagara Intl. (BUF) to McGhee Tyson (TYS) on a Thursday, with around 29 flights available. This gives you a good selection for your travel plans. Major airlines on this route include American Airlines, Delta, and United. Flight schedules are quite consistent throughout the week, so you'll have plenty of options no matter which day you choose to fly.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The most popular departure times for flights from Buffalo Niagara Intl. (BUF) to McGhee Tyson (TYS) are in the early morning, from 6am to 9am. Many major carriers, including American Airlines, Delta and United, offer flights during this window. This timing works well for travellers who want to get an early start on their journey.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
There are no nonstop flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson). The shortest flights typically involve one stop and take around 4 hours 48 minutes. Flights with two or more stops usually take longer, averaging about 10 hours. The distance between these two airports is approximately 912 kilometres. Keep in mind that actual travel times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
You can fly first class between BUF and TYS. First class cabins are available on Delta, United, and American Airlines.
How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Knoxville, TN (TYS) from Buffalo, NY (BUF)?
If you're planning to travel to Knoxville from Buffalo Niagara Intl. (BUF), you can fly directly into McGhee Tyson (TYS). Some flights may connect through major hubs like Liberty Intl. (EWR), O'Hare Intl. (ORD), or Washington Dulles Intl. (IAD) before reaching Knoxville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Roundtrip price
CA $404
Distance
906 km

Book with confidence

Buffalo to Alcoa Flights

The easy way to book your flights from Buffalo to Knoxville 

With Expedia, it’s simple to find and book flights to Knoxville from Buffalo whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to McGhee Tyson, too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Buffalo to Knoxville today, tomorrow, or this week.  

 

Save dollars with cheap flights from Buffalo Niagara Intl., BUF to McGhee Tyson, TYS 

Sort your search results by price to find great deals on your flight from Buffalo to Knoxville—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Knoxville from Buffalo currently is just CA $405 rising to CA $468.  

Here are more money-saving tips: 

  • Fly in October when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Knoxville  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Knoxville from Buffalo 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Knoxville with Expedia today.

Buffalo to Alcoa Flights

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