Book The Best Hotels in Varnville, SC for 2026 from CA $69 - Fully Refundable Options

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Our top choices for Varnville hotels

A hotel room with a bed, bedside tables, a large mirror, a bathtub, a sofa, and a television.

A covered corridor with a white railing, a hanging light fixture, and a view of the outside.

A restaurant with a counter, seating area, and a TV mounted on the wall.

A hallway with a wooden floor, a reception desk, a couch, and a door marked 'Employees Only'.

1. OYO Hampton South Carolina Hwy 278

Hampton

Mary

CA $152

CA $184 total

includes taxes & fees

Sep 22 - Sep 23

A hotel room with a large bed, two bedside lamps, a chair, a large window with curtains, and a wall-mounted air conditioner.

A hotel room with a flat-screen TV mounted on the wall, a desk with a microwave, a chair, and a lamp.

A blue armchair with a patterned fabric, positioned against a grey wall with a white lamp and plaid curtains in the background.

2. Palmetto Inn

Estill

Carnell

CA $94

CA $102 total

includes taxes & fees

Sep 22 - Sep 23

A hotel room with two beds, a TV, a desk, and a chair.

A compact kitchenette with a microwave, coffee maker, and a small refrigerator.

A coffee station with a Folgers coffee machine, red coffee dispensers, and a milk frother.

A circular swimming pool with a surrounding deck, equipped with lounge chairs and a fence.

3. Red Roof Inn Yemassee

Yemassee

Anthony

CA $103

CA $117 total

includes taxes & fees

Sep 22 - Sep 23

A Microtel Inn Suites by Wyndham with a parking lot and a red car parked in front.

A swimming pool with a white fence, a lifeguard chair, and a sign indicating no diving.

A modern hotel lobby with wooden counters, a digital screen, a coffee machine, and a tiled floor.

Two cold drink vending machines and a snack shelf stocked with various brands.

4. Microtel Inn & Suites by Wyndham Walterboro

Walterboro

Sarah

CA $132

CA $148 total

includes taxes & fees

Sep 23 - Sep 24

A hallway with a vending machine and a refrigerator.

A reception area with a desk, chairs, a coffee table, and a large window offering a view of the parking lot and trees.

A hotel room with two beds, a wooden headboard, a bedside table, a lamp, and a window with curtains.

5. Quality Inn Yemassee - Point South I-95

Yemassee

Debra

CA $87

CA $98 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A modern dining area with yellow and teal chairs, wooden tables, and a large window offering a view of greenery.

A hotel hallway with a blue carpet, white walls, and doors on both sides.

A gym with cardio equipment, weight machines, and a treadmill.

6. Comfort Inn & Suites Walterboro I-95

Walterboro

andrew

CA $141

CA $158 total

includes taxes & fees

Oct 11 - Oct 12

A modern breakfast area with a central island, wooden cabinets, and a sign that reads 'HAPPY BREAKFAST STARTS HERE.'

A Hampton Inn by Hilton hotel with a modern facade, a welcoming entrance, and a clear sky.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and a wall-mounted lamp.

A snack display with multiple shelves and refrigerated sections.

7. Hampton Inn Yemassee/Point South

Yemassee

Charlene

CA $194

CA $219 total

includes taxes & fees

Sep 28 - Sep 29

A modern living room with a sofa, a round table, a TV mounted on a wooden wall, and a kitchen area in the background.

A hotel room with a bed, a mounted TV, a mirror, and a wooden panel wall.

A self-service breakfast area with coffee machines, a microwave, and a beverage dispenser.

A modern living room with large windows, a ceiling fan, and a mix of seating including a sofa, armchairs, and ottomans.

8. Best Western Of Walterboro

Walterboro

Gregory

CA $123

CA $138 total

includes taxes & fees

Sep 28 - Sep 29

A reception desk with a Baymont Inn & Suites sign, a chandelier, and a fire extinguisher.

A Baymont Inn & Suites building with a prominent sign, a fountain, and statues in front.

A hotel room with two beds, a desk, a chair, a mirror, and a window.

A rectangular swimming pool with a metal fence around it, a paved walkway, and a grassy area with a hose.

9. Baymont by Wyndham Walterboro

Walterboro

Miguelina

CA $62

CA $69 total

includes taxes & fees

Sep 22 - Sep 23

A hotel lobby with seating arrangements, a television, a kitchen area, and a large window with curtains.

A reception desk at Days Inn with a 'Hello Sunshine' sign, a clock, and a framed certificate on the wall.

A swimming pool with lounge chairs and umbrellas, a building with balconies, and a sign indicating shallow water.

A hotel room with two beds, a desk with a TV, a chair, a small table, and a mirror.

10. Days Inn by Wyndham Walterboro

Walterboro

christopher

CA $96

CA $108 total

includes taxes & fees

Sep 23 - Sep 24

A room with a window view of a forest path, a white air conditioning unit, a grey upholstered bench, and a wall-mounted lamp.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

A hotel room with a wooden dining table, blue sofa, and a small wooden coffee table. A hallway leads to the bathroom.

A room with a wooden desk, a green office chair, a grey sofa, and a window with a view of trees and a building.

11. Holiday Inn Exp Walterboro by IHG

Walterboro

Jennifer

CA $207

CA $232 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a chair, a desk, and a mirror.

A kitchen with a dining table, chairs, a ceiling fan, a TV, and a door leading outside.

A reception area with a wooden desk, framed awards, and a red carpet with the hotel name.

12. Econo Lodge Walterboro I-95

Walterboro

anita

CA $65

CA $73 total

includes taxes & fees

Oct 12 - Oct 13

A spacious lobby with a coffee table, sofas, and a television. Large windows offer views of palm trees and a parking lot.

A spacious lobby with a polished tile floor, large windows, and a reception desk.

A reception area with a counter, chairs, and large windows offering a view of palm trees and a parking lot.

A spacious indoor area with large windows, wooden tables and chairs, and a view of palm trees and a road.

13. Econo Lodge Yemassee

Yemassee

Derek

CA $65

CA $74 total

includes taxes & fees

Oct 12 - Oct 13

A hotel room with two beds, a desk, a chair, and a TV.

A wooden gazebo with a green roof, surrounded by a grassy area and a wooden fence.

A modern living room with a sofa, two armchairs, a coffee table, and a large window providing a view.

A Red Roof Inn with a two-story structure, a covered parking area, and a palm tree in the foreground.

14. Red Roof Inn Walterboro

Walterboro

wendy

CA $70

CA $78 total

includes taxes & fees

Sep 24 - Sep 25

A Quality Inn hotel with a prominent sign, a covered entrance, and a parking lot.

A pool area with lounge chairs and umbrellas, a building with balconies, and a clear sky.

A reception desk with a 'Quality by Choice Hotels' sign, a Dell computer, and a stone-patterned wall.

A waffle maker with a digital display and a push button.

15. Quality Inn Walterboro I-95

Walterboro

Marvin

CA $88

CA $99 total

includes taxes & fees

Oct 11 - Oct 12

A reception area with a marble counter, a glass door entrance, and a wooden floor.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a framed picture on the wall.

A kitchen with a microwave, coffee maker, and fruit juice dispenser.

A reception area with a wooden wall, a sofa, a chair, and a potted plant.

16. Travelodge by Wyndham Walterboro

Walterboro

Gabriella

CA $80

CA $89 total

includes taxes & fees

Sep 22 - Sep 23

A spacious hotel lobby with a central bar area, multiple seating arrangements, and large windows providing natural light.

A swimming pool with lounge chairs, a fence, and a building with stone and brick exterior.

A snack display with various packaged snacks and beverages.

A rack of dumbbells with weights labeled 5 and 10.

17. Hampton Inn & Suites Walterboro

Walterboro

Lauren

CA $201

CA $225 total

includes taxes & fees

Sep 28 - Sep 29

A hotel with a covered front porch, a two-story building, and a parking lot with motorcycles.

A hotel bathroom with a granite countertop, a sink, a mirror, and a towel rack.

A restaurant interior with wooden tables and chairs, a coffee machine, a refrigerator, and a window with a view of the street.

A poolside area with a lifeguard chair, a pool ladder, and two white chairs.

18. Super 8 by Wyndham Walterboro

Walterboro

David

CA $63

CA $71 total

includes taxes & fees

Oct 5 - Oct 6

A hotel room with a bed, bedside lamps, a nightstand, a mirror, and a framed photo collage on the wall.

A pool area with lounge chairs, a pool, and a building with a 'Sleep Inn' sign.

A modern living room with a sofa, armchair, and coffee table, a desk with a computer, and a staircase leading to an upper level.

A living room with a sofa, armchair, and a small round table with a lamp and decorative items.

19. Sleep Inn Walterboro I-95

Walterboro

France

CA $118

CA $132 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, bedside tables, a desk, a TV, a window, and a door.

A two-story building with a brick facade, multiple windows, and a staircase leading to the upper level.

A bathroom with a granite countertop, a sink, a vanity with a mirror, and a microwave.

A Southern Inn hotel with a brick facade, orange doors, and a prominent blue sign.

20. Southern Inn By OYO Walterboro I-95

Walterboro

jesus

CA $62

CA $70 total

includes taxes & fees

Sep 22 - Sep 23

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Top Varnville Hotel Reviews

Baymont by Wyndham Walterboro

10/10 Excellent

"Very cheap! Staff was extremely helpful"

Quality Inn Walterboro I-95

10/10 Excellent

"No problems. Efficient. Comfortable beds. Nice continental. Friendly hosts"

Best Western Of Walterboro

10/10 Excellent

"As they say don’t judge a book by its cover! Room was renovated and it’s modern & spotless. Breakfast area is modern,clean & offers almost anything you could want both hot & cold choices!"

Microtel Inn & Suites by Wyndham Walterboro

10/10 Excellent

"We will mark this one as a favorite off of I95; thank you to the hotel for a great late night check in"

Comfort Inn & Suites Walterboro I-95

8/10 Good

"Bed was comfortable but old"

Sleep Inn Walterboro I-95

10/10 Excellent

"The room was clean, the breakfast was good, the location was perfect! Everything was good and good price!"

Holiday Inn Exp Walterboro by IHG

10/10 Excellent

"Hotel was very nice. All staff we came in contact with was friendly, polite, and cracked jokes with this crazy group of ladies. Will definitely stay here again when in the area."

Baymont by Wyndham Ridgeland I-95

8/10 Good

"Comfortable a clean room; Easy check-in and check-out - accomodated our late arrival."

OYO Hampton South Carolina Hwy 278

8/10 Good

"Front desk was terrible; no breakfast"