Title: Hotels by Best Western in Syracuse | Expedia.ca [Syracuse Travel Guide](https://expedia.ca/Syracuse.dx4912)[Hotels in Syracuse](https://expedia.ca/Syracuse-Hotels.d4912.Travel-Guide-Hotels)[Vacation Rentals in Syracuse](https://expedia.ca/Syracuse-Vacation-Rentals.d4912.Travel-Guide-VacationRentals)[Flights to Syracuse](https://expedia.ca/Cheap-Flights-To-Syracuse.d4912.Travel-Guide-Flights)[Things to do in Syracuse](https://expedia.ca/Things-To-Do-In-Syracuse.d4912.Travel-Guide-Activities)[Syracuse Car Rentals](https://expedia.ca/Car-Rentals-In-Syracuse.d4912.Car-Rental-Guide)[Syracuse Vacation Packages](https://expedia.ca/Syracuse.d4912.Destination-Travel-Guides) ![Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe](https://images.trvl-media.com/place/4912/0fad57c8-f045-437c-be3c-817a684ac32e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/4912/0fad57c8-f045-437c-be3c-817a684ac32e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 22 - Jan 23](https://www.expedia.ca/Hotel-Search?regionId=4912&startDate=2026-01-22&endDate=2026-01-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 23 - Jan 24](https://www.expedia.ca/Hotel-Search?regionId=4912&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=4912&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=4912&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSyracuse-Hotels-Best-Western.0-0-d4912--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSyracuse-Hotels-Best-Western.0-0-d4912--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Syracuse Hotel Reviews ![Ortea Palace Hotel, Sicily, Autograph Collection](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3b8d7262_y.jpg) ### Ortea Palace Hotel, Sicily, Autograph Collection 10/10 Excellent "Great hotel, great service. Well located, " [](https://expedia.ca/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) ![Palazzo Artemide - VRetreats](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg) ### Palazzo Artemide - VRetreats 10/10 Excellent "Very clean, elegant and comfortable. Pleasant and helpful staff. " [](https://expedia.ca/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Lanterne Magiche Ortigia](https://images.trvl-media.com/lodging/19000000/18710000/18704100/18704044/266affcc_y.jpg) ### Lanterne Magiche Ortigia 10/10 Excellent "Excellent. L'établissement est superbe et très bien placé. Les photos des appartements ne reflètent pas la beauté et le charme de ce lieu. Personnel accueillant et agréable. Je recommande. " [](https://expedia.ca/Syracuse-Hotels-Lanterne-Magiche-Ortigia.h18704044.Hotel-Information) ![Maniace Boutique Hotel Ortigia UNA Esperienze](https://images.trvl-media.com/lodging/110000000/109090000/109087400/109087329/9a2e90c5_y.jpg) ### Maniace Boutique Hotel Ortigia UNA Esperienze 10/10 Excellent "Room was spotless. The location and view were amazing. The staff is exceptional!" [](https://expedia.ca/Syracuse-Hotels-Maniace-Boutique-Hotel-Ortigia.h109087329.Hotel-Information) ![Algila' Ortigia Charme Hotel](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "Fantastic hotel! Large, lovely room in beautiful, completely renovated 19th century building that is steps from the waterfront. Terrific breakfast, very friendly, helpful staff. Highly recommend!" [](https://expedia.ca/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Grand Hotel Ortigia Siracusa](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f_y.jpg) ### Grand Hotel Ortigia Siracusa 10/10 Excellent "Stunning hotel and area on the waterfront in Ortigia. Strongly recommend everything except the restaurant. Food was marginal for the price with much better options close by" [](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Domus Mariae Albergo](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184_y.jpg) ### Domus Mariae Albergo 10/10 Excellent "Breakfast was fresh and the service was wonderfully. My balcony over looked the sea. They helped me with my bags and were very friendly. They spoke English which helped a lot." [](https://expedia.ca/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![L'Approdo delle Sirene](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/fe44f2b7_y.jpg) ### L'Approdo delle Sirene 10/10 Excellent "Clean room… nice view from the rooftop… excellent location!" [](https://expedia.ca/Syracuse-Hotels-LApprodo-Delle-Sirene.h2527263.Hotel-Information) ![Grand Hotel Villa Politi](https://images.trvl-media.com/lodging/2000000/1230000/1220700/1220650/73408607_y.jpg) ### Grand Hotel Villa Politi 10/10 Excellent "Great old “grand hotel”. Beautiful property. " [](https://expedia.ca/Syracuse-Hotels-Grand-Hotel-Villa-Politi.h1220650.Hotel-Information) ## Explore a world of travel with Expedia - More ways to book - [Book Best Western in Syracuse on Expedia.it ](https://www.expedia.it/Siracusa-Hotel-Best-Western.0-0-d4912--bBestWestern.Guida-Viaggi-Filtro-Hotel)