Book The Best Hotels in Southwest Missouri, MO for 2026 from CA $92 - Fully Refundable Options

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Our top choices for Southwest Missouri hotels

A modern lobby with a fireplace, seating area, and a reception desk with a 'Historic Route 66' sign.

1. La Quinta Inn & Suites by Wyndham Springfield Airport/Rte 66

Tom Watkins

Deborah

CA $158 total

includes taxes & fees

Nov 29 - Nov 30

A spacious room with leather sofas, a wooden coffee table, and large windows offering views of the outside.

2. Bass Pro Shops Angler's Lodge

Fassnight

David

CA $184 total

includes taxes & fees

Dec 15 - Dec 16

A modern cafe with a wooden counter, seating area with sofas and tables, and a snack bar in the background.

3. Tru by Hilton Springfield Downtown

Downtown Springfield

Gloria

CA $155 total

includes taxes & fees

Nov 29 - Nov 30

A modern kitchen area with a central island, stainless steel appliances, and a glass partition.

4. Drury Inn & Suites Springfield, MO

Springfield

Barbara

CA $167 total

includes taxes & fees

Dec 6 - Dec 7

A breakfast buffet area with various food items, including pastries, bread, and packaged snacks.

5. Best Western Premier Springfield Plaza District Hotel

Oak Grove

brett

CA $133 total

includes taxes & fees

Nov 23 - Nov 24

A modern hotel lobby with a sofa, a coffee table, and a reception desk.

6. Baymont by Wyndham Springfield I-44

Doling

Sharilyn

CA $144 total

includes taxes & fees

Nov 15 - Nov 16

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

7. Clarion Pointe Springfield Southeast

Galloway Village

Cesar

CA $137 total

includes taxes & fees

Dec 6 - Dec 7

A spacious outdoor area with a wooden structure and a large building with multiple windows.

8. Holiday Inn Express & Suites Springfield North by IHG

Springfield

Charles

CA $160 total

includes taxes & fees

Dec 13 - Dec 14

A spacious living area with a brick fireplace, modern sofas, a coffee table, and a chandelier.

9. Best Western Coach House

Doling

Kimberly

CA $138 total

includes taxes & fees

Nov 29 - Nov 30

A hotel entrance with a covered driveway, stone pillars, and a glass door entrance.

10. Best Western Plus Springfield Airport Inn

Springfield

Charlotte

CA $158 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with multiple seating areas, a piano, and a large wall with leaf decorations.

11. DoubleTree by Hilton Springfield

Doling

Nancy

CA $188 total

includes taxes & fees

Nov 22 - Nov 23

A spacious living area with a large island table, comfortable seating, and a view of an outdoor patio.

12. Best Western Courtview Hotel

Galloway Village

Trevar

CA $131 total

includes taxes & fees

Nov 15 - Nov 16

A multi-level hotel atrium with a central courtyard, multiple floors, and various seating areas.

13. University Plaza Hotel and Convention Center Springfield

Downtown Springfield

Irvin

CA $160 total

includes taxes & fees

Nov 26 - Nov 27

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

14. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland

Phillip

CA $149 total

includes taxes & fees

Dec 13 - Dec 14

A modern building with a prominent V-shaped entrance and large glass windows.

15. Hotel Vandivort

Downtown Springfield

Andrew

CA $277 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio area with red seating, a fire feature, and tables and chairs.

16. Homewood Suites by Hilton Springfield Medical District

Southside

Mark

CA $187 total

includes taxes & fees

Nov 22 - Nov 23

A spacious indoor lobby with a reflective floor, seating areas, and large windows allowing natural light.

17. Oasis Hotel & Conv. Center, an Ascend Collection Hotel

Parkwood

rory

CA $165 total

includes taxes & fees

Dec 15 - Dec 16

An outdoor patio with a fire pit, seating, and a view of the backyard.

18. Hampton Inn Springfield-Southeast

Galloway Village

teresa

CA $178 total

includes taxes & fees

Nov 29 - Nov 30

A rustic bathroom with a vintage bathtub, wooden walls, a large mural of a historical street scene, and a wooden cabinet.

19. Best Western Route 66 Rail Haven

Walnut Street

Michael

CA $134 total

includes taxes & fees

Nov 29 - Nov 30

A hotel with a covered entrance, outdoor seating, and a parking area.

20. Days Inn by Wyndham Battlefield Rd/Hwy 65

Galloway Village

Alberto

CA $111 total

includes taxes & fees

Dec 1 - Dec 2

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Stay near popular Southwest Missouri attractions

Silver Dollar City

9.2/10 (2,946 reviews)

Attend an old bluegrass or country music concert in this 1880s-style theme park full of exhilarating rides, intriguing shows and a friendly atmosphere.

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Learn more about Southwest Missouri

Great entertainment, shopping, and popular sights from Silver Dollar City to Branson Landing—explore Southwest Missouri, a destination also known for its sports teams.

See all hotels in Southwest Missouri

A sign for the Visitor Center at Wilson's Creek National Battlefield.

Top Southwest Missouri Hotel Reviews

A cozy living room with a fireplace, wooden decor, and a fireplace mantle with a deer figurine.

Lodge Of The Ozarks

Branson Theater District

10/10 Excellent

Faye

A large indoor swimming pool with a wooden ceiling and skylights, surrounded by lounge chairs and a brick floor.

Comfort Inn & Suites Branson Meadows

Branson Meadows

10/10 Excellent

John

A spacious hotel lobby with a central seating area, multiple tables, and a large chandelier.

Homewood Suites by Hilton Joplin

Joplin

10/10 Excellent

Loved, loved, loved this hotel. The staff were so friendly and helpful and gave us all the help we needed. We arrived early and our room wasn't quite ready so we grabbed a coffee and checked out the hotel pool and fitness area. The room was ready very quickly and the front desk staff came looking for us to give us our room keys! We were thrilled that they didn't wait for us to go to them but sought us out! Thank you so much for all the little touches that make a difference in helping others feel...

Karen