What is South Jefferson like?

Guests are sure to enjoy their time checking out all that Roanoke's South Jefferson neighborhood has to offer.

What's a favorite place to stay in South Jefferson?

Based on our traveler data, SpringHill Suites by Marriott Roanoke is one of the top choices for your stay in South Jefferson. This hotel offers free breakfast and a restaurant.

If I need to cancel my hotel reservation in South Jefferson, will I receive a refund?

Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in South Jefferson.

What is there to do around this Roanoke neighborhood?

A few places to visit in the area around South Jefferson include River's Edge Sports Complex, Roanoke City Public Library, and Mill Mountain Star. When you're sightseeing in Roanoke, Mill Mountain Zoo and Arts Council of the Blue Ridge are also worth a stop.

10 Best Hotels in South Jefferson, Roanoke for 2026

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Our top choices for South Jefferson hotels

A spacious hotel lobby with a large seating area, a bar, and a view of greenery outside.

1. SpringHill Suites by Marriott Roanoke

South Jefferson

Joseph

CA $227 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio with a stone fire pit, turquoise chairs, and a table.

2. Spark by Hilton Roanoke Civic Center

Gainsboro, 2.6 km from South Jefferson

William

CA $117 total

includes taxes & fees

Nov 19 - Nov 20

A modern hotel with a covered entrance, multiple floors, and a parking area.

3. Holiday Inn Express & Suites Roanoke – Civic Center by IHG

Williamson Road, 2.9 km from South Jefferson

Nicholas

CA $147 total

includes taxes & fees

Dec 3 - Dec 4

4. Hampton Inn & Suites Roanoke-Downtown

Downtown Roanoke, 1.4 km from South Jefferson

William M

CA $218 total

includes taxes & fees

Nov 22 - Nov 23

A breakfast area with wooden flooring, red upholstered chairs, a buffet counter, and large windows offering a view of greenery.

5. Comfort Inn Airport

Airport, 6.7 km from South Jefferson

Jorge

CA $130 total

includes taxes & fees

Nov 22 - Nov 23

A brick building with a sign reading "The West End Flats."

6. The West End Flats

West End, 1.8 km from South Jefferson

Arnold

CA $138 total

includes taxes & fees

Nov 16 - Nov 17

A modern lobby with a reception desk, a staircase with a green accent wall, and a seating area with a sofa and armchair.

7. Sleep Inn Tanglewood

5.2 km from South Jefferson

Elena

CA $102 total

includes taxes & fees

Dec 3 - Dec 4

8. Extended Stay America Premier Suites - Roanoke - Vinton

4.3 km from South Jefferson

CA $160 total

includes taxes & fees

Dec 1 - Dec 2

An outdoor seating area with a fire feature, a covered patio, and a view of the surrounding landscape.

9. La Quinta Inn & Suites By Wyndham Roanoke Hollins/I-81

Alpine Hills, 11.1 km from South Jefferson

Adam

CA $161 total

includes taxes & fees

Nov 8 - Nov 9

A modern hotel lobby with a sofa, a coffee station, and a refrigerator.

10. La Quinta Inn & Suites by Wyndham Roanoke Salem

10.6 km from South Jefferson

Doretta

CA $137 total

includes taxes & fees

Dec 1 - Dec 2

A hotel with a sign reading "QUALITY INN" and a well-lit entrance.

11. Quality Inn Tanglewood

Franklin-Colonial, 3.7 km from South Jefferson

Tina

CA $74 total

includes taxes & fees

Dec 3 - Dec 4

A reception area with a red sofa, a potted plant, a travel information board, and a chandelier.

12. Econo Lodge Roanoke Civic Center

Williamson Road, 2.8 km from South Jefferson

Sierra

CA $109 total

includes taxes & fees

Nov 8 - Nov 9

A grand lobby with ornate doors, a chandelier, marble flooring, and a central seating area.

13. The Liberty Trust

Downtown Roanoke, 1.5 km from South Jefferson

Ben

CA $237 total

includes taxes & fees

Nov 8 - Nov 9

A Country Inn & Suites hotel with a modern design, featuring a large signboard, well-maintained landscaping, and a parking area.

14. Country Inn & Suites by Radisson, Roanoke, VA

Alpine Hills, 10.9 km from South Jefferson

William

CA $142 total

includes taxes & fees

Dec 1 - Dec 2

A modern living room with a grey sofa, a round coffee table, a floor lamp, and a vase with flowers.

15. The Promissory Hotel

Downtown Roanoke, 1.5 km from South Jefferson

Lily

CA $222 total

includes taxes & fees

Dec 3 - Dec 4

A hotel room with a bed, a desk, a chair, a lamp, and a bathroom visible through an open door.

16. Colony House Motor Lodge

Franklin-Colonial, 3.4 km from South Jefferson

Ana

CA $172 total

includes taxes & fees

Dec 5 - Dec 6

A spacious lobby with a curved balcony, a staircase, and multiple seating areas.

17. Hampton Inn Salem East - Electric Road

7.9 km from South Jefferson

Cristelle

CA $155 total

includes taxes & fees

Dec 2 - Dec 3

A modern hotel room with two beds, a sofa, a small wooden table, and a large window.

18. Hyatt Place Roanoke Airport/Valley View Mall

Roundhill, 6.1 km from South Jefferson

Nancy

CA $187 total

includes taxes & fees

Nov 15 - Nov 16

A Holiday Inn Express hotel with a brick facade, a covered entrance, and a parking lot.

19. Holiday Inn Express & Suites Salem by IHG

10.3 km from South Jefferson

Kyle

CA $144 total

includes taxes & fees

Dec 2 - Dec 3

A modern kitchen with a green wall, white ceiling, and a counter with various items. There are multiple tables and chairs, some with green chairs.

20. Spark by Hilton Roanoke Airport

Airport, 6.5 km from South Jefferson

Caitlyn

CA $122 total

includes taxes & fees

Nov 15 - Nov 16

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Compare popular hotels in South Jefferson

Property	Star rating	Guest rating
SpringHill Suites by Marriott Roanoke	3.0 star property	9.0 Wonderful 1,003 reviews	View
Spark by Hilton Roanoke Civic Center	2.5 star property	9.0 Wonderful 430 reviews	View
Holiday Inn Express & Suites Roanoke – Civic Center by IHG	2.5 star property	9.2 Wonderful 1,003 reviews	View
Colony House Motor Lodge	2.5 star property	9.8 Exceptional 217 reviews	View
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton	4.0 star property	9.6 Exceptional 1,000 reviews	View

Where to stay in South Jefferson

Find the best South Jefferson areas and neighborhoods for the activities you enjoy most. Learn more about South Jefferson

A row of historic buildings with vintage signage, including a Coca-Cola mural and a sign for a rooftop patio.

Downtown Roanoke

While visiting Downtown Roanoke, you might make a stop by sights like Center in the Square and Virginia Museum of Transportation.

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A cityscape at dusk with illuminated buildings and a winding road.

Old Southwest

Boasting a mix of architectural styles like Queen Anne and Colonial Revival, this historic district home to Roanoke's first public park, Highland Park, and the Beth Israel Synagogue, with commercial areas concentrated along Franklin Road.

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Franklin-Colonial

Franklin-Colonial might not have many top sights, but Tanglewood Mall and River's Edge Sports Complex are two attractions nearby that you can check out.

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Wasena

While Wasena isn't home to many top sights, Jefferson Center and Virginia Museum of Transportation are some notable places to visit nearby.

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Gainsboro

Though Gainsboro might not have many top sights, you can venture to the surrounding area to see attractions like Berglund Center and Taubman Museum of Art.

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Top South Jefferson Hotel Reviews

Spark by Hilton Roanoke Civic Center

8/10 Good

"The room is spacious with 2 queen beds, a nice sized desk and a great working fridge. The bathroom is very clean with lots of towels. The parking lot is well lit and has ample spaces. I booked the hotel via Expedia which offered a very reasonable price. Highly recommended!"

The West End Flats

8/10 Good

"We stayed one night with our dog. It was perfect for us. Had a nice courtyard for her to run around, completely fenced in with a gas grill and fire pit to enjoy. Room was very clean, great kitchen w/full-size fridge, microwave, coffee maker, dishwasher and oven. Only negative (and reason for 4 stars) was the couch… uncomfortable, and tiny. There was also no additional seats or table to eat at other than coffee table. Would recommend."

Comfort Inn & Suites Troutville-Roanoke North

10/10 Excellent

"This is not the 4 seasons, but as a budget hotel it hit all the marks I needed on a 1 day stop. The room was clean. The bathroom was clean. The bed was comfortable. Breakfast was easy and decent. Staff was polite, helpful, clean, and well functioning. Only downside I could hear the highway (low hum) from my room, but it wasn't an issue. The hotel was fairly full of travelers on a random fall weekday - many of them seemed to be contract workers, and others were people passing through like me (I was on business). Would stay again - nothing negative to report. Price was excellent."

Baymont by Wyndham Salem Roanoke Area

8/10 Good

"Only stayed one night but the property was clean and looked like it had just been updated. They served breakfast in a nice large room, but we didn't have time to eat breakfast. Parking was convenient and location of hotel was close to restaurants and interstate. Receptionist was very friendly and personable."

Hotels in South Jefferson, Roanoke

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Be picky

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Our top choices for South Jefferson hotels

1. SpringHill Suites by Marriott Roanoke

2. Spark by Hilton Roanoke Civic Center

3. Holiday Inn Express & Suites Roanoke – Civic Center by IHG

4. Hampton Inn & Suites Roanoke-Downtown

5. Comfort Inn Airport

6. The West End Flats

7. Sleep Inn Tanglewood

8. Extended Stay America Premier Suites - Roanoke - Vinton

9. La Quinta Inn & Suites By Wyndham Roanoke Hollins/I-81

10. La Quinta Inn & Suites by Wyndham Roanoke Salem

11. Quality Inn Tanglewood

12. Econo Lodge Roanoke Civic Center

13. The Liberty Trust

14. Country Inn & Suites by Radisson, Roanoke, VA

15. The Promissory Hotel

16. Colony House Motor Lodge

17. Hampton Inn Salem East - Electric Road

18. Hyatt Place Roanoke Airport/Valley View Mall

19. Holiday Inn Express & Suites Salem by IHG

20. Spark by Hilton Roanoke Airport

Compare popular hotels in South Jefferson

Where to stay in South Jefferson

Downtown Roanoke

Old Southwest

Franklin-Colonial

Wasena

Gainsboro

Top South Jefferson Hotel Reviews

Spark by Hilton Roanoke Civic Center

Frequently asked questions