The best area to stay in São Vicente is Mindelo, particularly around the city centre and its waterfront.Mindelo is the main hub of São Vicente and offers a convenient base for exploring the island. The city centre is very walkable, with a mix of historic architecture, local markets, and cultural sites. The main square, Praça Nova, is a central gathering point, and the nearby Rua da Ribeira Grande is known for its shops and eateries. The waterfront promenade, Avenida Marginal, provides pleasant views of the bay and the marina.For couples looking for a mix of culture and relaxation, staying near the city centre is ideal. You'll be within easy reach of the vibrant music scene, particularly around Rua Lisboa, and can enjoy leisurely strolls along the harbour. The area also provides easy access to the ferry terminal for day trips to Santo Antão.Families will also find Mindelo a good option, especially if they prefer having amenities and activities close at hand.