Title: Book The Best Hotels in Santa Isabel for 2025 from CA $58 - Fully Refundable Options - Expedia.ca

  

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# Find hotels in Santa Isabel from CA $58

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## Go beyond your typical stay in Santa Isabel

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico&regionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&travelerType=family_friendly)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico&regionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=POOL)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Mexicali%2C+Baja+California%2C+Mexico&regionId=553248635975869828&latLong=32.632687%2C-115.577461&adults=2&startDate=2025-10-10&d1=2025-10-10&endDate=2025-10-12&d2=2025-10-12&amenities=PETS)

## Check prices for these dates

Tonight

[Sep 26 - Sep 27](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-09-26&endDate=2025-09-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975869828&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 72 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/a39bc3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/2d1b8a75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 outdoor pools, open 10:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/22600/22592/883c858a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Araiza Mexicali

Mexicali

8.6/10

Excellent

(1602)

"Great place to vacay "

CA $147

CA $166 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information)

![Daily cooked-to-order breakfast (MXN 290 per person)](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/3a4ef50e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/8e09f6a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite Ejecutiva King | Living area](https://images.trvl-media.com/lodging/1000000/610000/600500/600405/a09279f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Real Inn Mexicali

Civic Center

8.2/10

Very good

(1472)

"Great place "

CA $95

CA $108 total

includes taxes & fees

Oct 13 - Oct 14

[](https://www.expedia.ca/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/4d789164.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/5d2422db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/70e7eb7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/50e75016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### One Mexicali

Mexicali

7.8/10

Good

(1013)

"Food was delicious. "

CA $88

CA $101 total

includes taxes & fees

Sep 29 - Sep 30

[](https://www.expedia.ca/Mexicali-Hotels-One-Mexicali.h17577142.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/e443b787.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/100934ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Habitacion ejecutiva, dos camas](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/179fc335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/ee9d5f67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Siesta Real

Mexicali

8.2/10

Very good

(836)

"Nice and friendly place "

CA $104

CA $117 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Siesta-Real.h18301092.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/9be1b557.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/0cad0e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/6e6f2982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/3c27d24e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City Express Plus by Marriott Mexicali

Mexicali

8.6/10

Excellent

(876)

"Good location"

CA $101

CA $114 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information)

![Interior entrance](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/9bc6d08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/677d7bf3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/90810982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/25000000/24090000/24081400/24081334/5df61ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sleep Inn Mexicali

Mexicali

8.2/10

Very good

(1010)

"They have good breakfast "

CA $92

CA $112 total

includes taxes & fees

Sep 29 - Sep 30

[](https://www.expedia.ca/Mexicali-Hotels-Sleep-Inn-Mexicali.h24081334.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/d0790816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/5a6c7074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bungalow, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/440000/437500/437408/abb801cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Lucerna Mexicali

Mexicali

9.2/10

Wonderful

(1384)

"Great place!"

CA $124

CA $140 total

includes taxes & fees

Oct 20 - Oct 21

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/edfeecd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/f5fe57d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room | Bathroom](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/54625619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/11000000/10080000/10071600/10071570/49970db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Azteca de Oro Mexicali

Mexicali

7.6/10

Good

(403)

"Exelente"

CA $49

CA $55 total

includes taxes & fees

Sep 29 - Sep 30

[](https://www.expedia.ca/Mexicali-Hotels-Azteca-De-Oro-Mexicali.h10071570.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/fc9185d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/b6aa67b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/1b6e837a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/13000000/12510000/12506500/12506422/d5c9e706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Mexicali by IHG

Mexicali

9.4/10

Exceptional

(1000)

"Great hotel, location and service"

CA $170

CA $192 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Mexicali-Hotels-Holiday-Inn-Express-Suites-Mexicali.h12506422.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/586cc6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/3acf53a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Multiple Beds](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/e6ace82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Mexicali

Mexicali

9.4/10

Exceptional

(1020)

"The room was clean, lots of restaurants and breakfast was delicious. "

CA $146

CA $165 total

includes taxes & fees

Oct 10 - Oct 11

[](https://www.expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/5a8679ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/fd4f05d0_edited_7172.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed | View from room](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/67882e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/18000000/17970000/17969200/17969178/4c46b9cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Extended Suites Mexicali Cataviña

Mexicali

8.0/10

Very good

(2091)

"Love the location, very clean rooms and very safe "

CA $97

CA $118 total

includes taxes & fees

Oct 28 - Oct 29

[](https://www.expedia.ca/Mexicali-Hotels-Extended-Suites-Mexicali-Catavina.h17969178.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/2e8db822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/975cd623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/da930419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Double Room](https://images.trvl-media.com/lodging/1000000/30000/22600/22599/f23e4d26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Calafia Hotel

Eguía

8.2/10

Very good

(1013)

"Bussiness Friendly, nice location. "

CA $106

CA $120 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/Mexicali-Hotels-Calafia-Hotel.h22599.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3b6504b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/e439c29a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/3ea225c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1670000/1661300/1661225/218fae64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City Express by Marriott Mexicali

Mexicali

8.2/10

Very good

(1006)

"The cleanliness of the property is exceptional, easy parking and the staff was super helpful and nice. Very well recommended!"

CA $95

CA $107 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/Mexicali-Hotels-City-Express-Mexicali.h1661225.Hotel-Information)

![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/48bb48a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/d9075b51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/0b1abeec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, 2 Double Beds](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/7d528f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fiesta Inn Mexicali

Civic Center

8.2/10

Very good

(1002)

"Great Hotel "

CA $95

CA $110 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/Mexicali-Hotels-Fiesta-Inn-Mexicali.h1152269.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/fbfdde79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/1ad6da57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/w4000h2662x0y0-04bf55ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/5000000/4620000/4610900/4610858/3b84677b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City Express Junior by Marriott Mexicali

Mexicali

7.8/10

Good

(1008)

"- staff accommodated my needs friendly friendly and place was quiet enough to relax "

CA $95

CA $107 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/Mexicali-Hotels-City-Express-Junior-Mexicali.h4610858.Hotel-Information)

![Daily continental breakfast (MXN 300 per person)](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/980bccaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/4796b47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/f2c1f75c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed](https://images.trvl-media.com/lodging/1000000/920000/916300/916204/21f7b42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Colonial Mexicali

Civic Center

7.8/10

Good

(1016)

"It was affordable, the room was clean and in great condition"

CA $111

CA $126 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Colonial-Mexicali.h916204.Hotel-Information)

![Deluxe Suite, Jetted Tub](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/c266de1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite, Jetted Tub](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/0d0da065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Suite](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/d6e80519.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102640000/102634000/102634000/11d3da4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel Cies

Mexicali

9.2/10

Wonderful

(46)

"Great place to stay awesome service "

CA $71

CA $83 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Mexicali-Hotels-Motel-Cies.h102634000.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/2ef4393d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/c64aab50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, Multiple Beds](https://images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/c2ed0c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard by Marriott Mexicali

Mexicali

9.4/10

Exceptional

(752)

"Very clean and new hotel "

CA $152

CA $172 total

includes taxes & fees

Oct 3 - Oct 4

[](https://www.expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/19520a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/07182baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/926da4c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/19000000/18310000/18300200/18300174/25e2656f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Cosmos Don Carlos

Eguía

8.0/10

Very good

(470)

"Great stay!"

CA $64

CA $73 total

includes taxes & fees

Sep 29 - Sep 30

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Cosmos-Don-Carlos.h18300174.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/b9040e72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Triple Room](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/0624ab03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/a66b0fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759903/cdbb41d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Hacienda del Indio

Mexicali

7.2/10

Good

(123)

"The room was clean and the parking was safe"

CA $45

CA $55 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/Mexicali-Hotels-Hotel-Hacienda-Del-Indio.h18759903.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12&regionId=553248635975869828&adults=2&sort=RECOMMENDED&openPlayBack=true)

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Save an average of 15% on thousands of hotels when you're signed in

[Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d553248635975869828.Travel-Guide-Hotels)

### Stay near popular Santa Isabel attractions

[](https://expedia.ca/Hospital-De-La-Familia-Hotels.0-l553248635977407856-0.Travel-Guide-Filter-Hotels)

#### Hospital de la Familia

Though Hospital de la Familia might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635977407856)

[](https://expedia.ca/Hospital-Almater-SA-De-CV-Hotels.0-l553248635998002058-0.Travel-Guide-Filter-Hotels)

#### Hospital Almater SA de CV

Though Hospital Almater SA de CV might be what brings you to town, perhaps you'll have a chance to explore more of Mexicali while you are here.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635998002058)

## More cheap stays in Santa Isabel

![Fairfield Inn & Suites by Marriott Mexicali](https://images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Fairfield Inn & Suites by Marriott Mexicali

Calzada Manuel Gomez Morin 856, Colonia Rivera, Mexicali, BC

CA $146

CA $165 total

Oct 10 - Oct 11

includes taxes & fees

9.4/10 Exceptional! (1,016 reviews)

[](https://expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information)

![Motel Las Fuentes](https://images.trvl-media.com/lodging/19000000/18760000/18760000/18759923/794b14f4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel Las Fuentes

Blvd Lopez Mateos 1655, Colonia Zacatecas, Mexicali, BC

CA $47

CA $58 total

Sep 28 - Sep 29

includes taxes & fees

7.8/10 Good! (142 reviews)

[](https://expedia.ca/Mexicali-Hotels-Motel-Las-Fuentes.h18759923.Hotel-Information)

![HOTEL DON QUIJOTE](https://images.trvl-media.com/lodging/112000000/111350000/111343500/111343437/6318d665_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### HOTEL DON QUIJOTE

Calz Independencia Independencia, 1782, Mexicali, BC

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=111343437&PinnedHotelID=111343437&HadPinnedHotel=true&regionId=553248635975869828)

6.8/10 (13 reviews)

[](https://expedia.ca/Mexicali-Hotels-HOTEL-DON-QUIJOTE.h111343437.Hotel-Information)

![Hotel Misión Plaza Mexicali](https://images.trvl-media.com/lodging/102000000/101490000/101486400/101486351/17b18c98_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Misión Plaza Mexicali

366 Av. Francisco I. Madero, Mexicali, BC

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=101486351&PinnedHotelID=101486351&HadPinnedHotel=true&regionId=553248635975869828)

7.2/10 Good! (46 reviews)

[](https://expedia.ca/Tijuana-Hotels-Hotel-Mision-Plaza-Mexicali.h101486351.Hotel-Information)

![Motel Diana ](https://images.trvl-media.com/lodging/118000000/117770000/117766600/117766546/9ba5b8f3_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel Diana

200 Av. Tabasco Loma Linda, Mexicali, BC

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=117766546&PinnedHotelID=117766546&HadPinnedHotel=true&regionId=553248635975869828)

10/10 Exceptional! (1 review)

[](https://expedia.ca/Mexicali-Hotels-Motel-Diana.h117766546.Hotel-Information)

![City Express Plus BY Marriott Mexicali](https://images.trvl-media.com/lodging/46000000/45180000/45176700/45176688/e9d65422_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### City Express Plus BY Marriott Mexicali

Av Republica de Cuba 39, Mexicali, BCN

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F10%2F2025&endDate=12%2F10%2F2025&selected=45176688&PinnedHotelID=45176688&HadPinnedHotel=true&regionId=553248635975869828)

[](https://expedia.ca/Mexicali-Hotels-City-Express-Plus-BY-Marriott-Mexicali.h45176688.Hotel-Information)

## Recent reviews of Santa Isabel hotels

![One Mexicali](//images.trvl-media.com/lodging/18000000/17580000/17577200/17577142/4d789164_y.jpg)

### One Mexicali

5/5 Excellent

Relax

"El hotel es sencillo tiene todo lo indispensable, el desayuno esta muy bueno. Muy buen servicio "

A verified traveller stayed at One Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-One-Mexicali.h17577142.Hotel-Information)

![Hotel Araiza Mexicali](//images.trvl-media.com/lodging/1000000/30000/22600/22592/185f4103_y.jpg)

### Hotel Araiza Mexicali

5/5 Excellent

"Exellent"

A verified traveller stayed at Hotel Araiza Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Hotel-Araiza-Mexicali.h22592.Hotel-Information)

![Hotel Lucerna Mexicali](//images.trvl-media.com/lodging/1000000/440000/437500/437408/8ef53b31_y.jpg)

### Hotel Lucerna Mexicali

5/5 Excellent

"Nice facilities "

A verified traveller stayed at Hotel Lucerna Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Hotel-Lucerna-Mexicali.h437408.Hotel-Information)

![Fiesta Inn Mexicali](//images.trvl-media.com/lodging/2000000/1160000/1152300/1152269/48bb48a1_y.jpg)

### Fiesta Inn Mexicali

5/5 Excellent

"The only thing is that they put down breakfast including and no we got charged 630 pesos"

A verified traveller stayed at Fiesta Inn Mexicali

Posted 5 days ago

[](https://expedia.ca/Mexicali-Hotels-Fiesta-Inn-Mexicali.h1152269.Hotel-Information)

![Hotel Siesta Real](//images.trvl-media.com/lodging/19000000/18310000/18301100/18301092/e443b787_y.jpg)

### Hotel Siesta Real

5/5 Excellent

"Nice and friendly place "

A verified traveller stayed at Hotel Siesta Real

Posted 6 days ago

[](https://expedia.ca/Mexicali-Hotels-Hotel-Siesta-Real.h18301092.Hotel-Information)

![Fairfield Inn & Suites by Marriott Mexicali](//images.trvl-media.com/lodging/34000000/33640000/33638200/33638137/a02730fc_y.jpg)

### Fairfield Inn & Suites by Marriott Mexicali

5/5 Excellent

"Great staff & really clean"

A verified traveller stayed at Fairfield Inn & Suites by Marriott Mexicali

Posted 6 days ago

[](https://expedia.ca/Mexicali-Hotels-Fairfield-Inn-Suites-By-Marriott-Mexicali.h33638137.Hotel-Information)

![Courtyard by Marriott Mexicali](//images.trvl-media.com/lodging/71000000/70920000/70919700/70919640/35c16f11_y.jpg)

### Courtyard by Marriott Mexicali

5/5 Excellent

"clean property and helpful staff"

A verified traveller stayed at Courtyard by Marriott Mexicali

Posted 7 days ago

[](https://expedia.ca/Mexicali-Hotels-Courtyard-By-Marriott-Mexicali.h70919640.Hotel-Information)

![Real Inn Mexicali](//images.trvl-media.com/lodging/1000000/610000/600500/600405/928ca1d8_y.jpg)

### Real Inn Mexicali

5/5 Excellent

"Vegan food items "

A verified traveller stayed at Real Inn Mexicali

Posted 8 days ago

[](https://expedia.ca/Mexicali-Hotels-Real-Inn-Mexicali.h600405.Hotel-Information)

![City Express Plus by Marriott Mexicali](//images.trvl-media.com/lodging/45000000/44950000/44945400/44945342/9be1b557_y.jpg)

### City Express Plus by Marriott Mexicali

5/5 Excellent

"Good location"

A verified traveller stayed at City Express Plus by Marriott Mexicali

Posted 9 days ago

[](https://expedia.ca/Mexicali-Hotels-City-Express-Plus-Mexicali.h44945342.Hotel-Information)

## Frequently asked questions

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Isabel hotel for you.

### How can I save on a Santa Isabel hotel booking with Expedia?

> Members always get our best prices. Find our best Santa Isabel hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Santa Isabel hotel?

> Prices for hotels in Santa Isabel often vary, but you can find a great deal from CA $58 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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